{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T04:26:19Z","timestamp":1740111979713,"version":"3.37.3"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,2,28]],"date-time":"2021-02-28T00:00:00Z","timestamp":1614470400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Left ventricular assist devices provide circulatory support to heart failure patients while awaiting a suitable donor heart. However, with their increased duration of therapy, complications are seen frequently. Although coagulation disorders (bleeding and thrombosis) are the most common complications, infection is also a major complication associated with significant morbidity. We report a case of a 53-year-old male with a left ventricular assist device who presented with driveline infection. He subsequently developed pancytopenia and was diagnosed with haemophagocytosis. Immediate treatment with intravenous immunoglobulin and methylprednisolone was started. His blood cell count returned to normal levels and the patient became eligible for heart transplantation again. Our case represents the rare occurrence of haemophagocytosis in a patient, which, if unnoticed, could lead to fatal consequences.<\/jats:p>","DOI":"10.1093\/ejcts\/ezab102","type":"journal-article","created":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T20:35:28Z","timestamp":1613507728000},"page":"717-718","source":"Crossref","is-referenced-by-count":0,"title":["Haemophagocytic lymphohistiocytosis in a patient with left ventricular assist device"],"prefix":"10.1093","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2493-0558","authenticated-orcid":false,"given":"Defne G\u00fcne\u015f","family":"Ergi","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Ege University Faculty of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3566-5937","authenticated-orcid":false,"given":"Ander","family":"Dorken Gallastegi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Ege University Faculty of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eren","family":"Arslan","sequence":"additional","affiliation":[{"name":"Department of Hematology, Ege University Faculty of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00dcmit","family":"Kahraman","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Ege University Faculty of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,2,28]]},"reference":[{"key":"2021091118374631300_ezab102-B1","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1056\/NEJMoa1900486","article-title":"A fully magnetically levitated left ventricular assist device\u2014final report","volume":"380","author":"Mehra","year":"2019","journal-title":"N Engl J Med"},{"key":"2021091118374631300_ezab102-B2","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.healun.2019.01.007","article-title":"Epidemiology of infection in mechanical circulatory support: a global analysis from the ISHLT Mechanically Assisted Circulatory Support registry","volume":"38","author":"Hannan","year":"2019","journal-title":"J Heart Lung Transplant"},{"key":"2021091118374631300_ezab102-B3","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/pbc.21039","article-title":"HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis","volume":"48","author":"Henter","year":"2007","journal-title":"Pediatr Blood Cancer"},{"key":"2021091118374631300_ezab102-B4","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/S0735-1097(17)34253-5","article-title":"Hemophagocytic Lymphohistiocytosis associated with implantation of ventricular assist devices and outcomes following subsequent orthotropic heart transplantation (OHT)","volume":"69","author":"Cheng","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2021091118374631300_ezab102-B5","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1016\/S0003-4975(03)00480-6","article-title":"Interactions between the recipient immune system and the left ventricular assist device surface: immunological and clinical implications","volume":"75","author":"Itescu","year":"2003","journal-title":"Ann Thorac Surg"}],"container-title":["European Journal of Cardio-Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ejcts\/article-pdf\/60\/3\/717\/40350369\/ezab102.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ejcts\/article-pdf\/60\/3\/717\/40350369\/ezab102.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,11]],"date-time":"2021-09-11T18:37:55Z","timestamp":1631385475000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejcts\/article\/60\/3\/717\/6154409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,28]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,2,28]]},"published-print":{"date-parts":[[2021,9,11]]}},"URL":"https:\/\/doi.org\/10.1093\/ejcts\/ezab102","relation":{},"ISSN":["1010-7940","1873-734X"],"issn-type":[{"type":"print","value":"1010-7940"},{"type":"electronic","value":"1873-734X"}],"subject":[],"published-other":{"date-parts":[[2021,9,1]]},"published":{"date-parts":[[2021,2,28]]}}}