{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:17:36Z","timestamp":1782865056280,"version":"3.54.5"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T00:00:00Z","timestamp":1616976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Ross Procedure and Adult congenital Cardiac Surgery trust"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u2002<\/jats:title>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The aim of this study was to investigate the long-term outcomes following right ventricle-to-pulmonary artery (RV-to-PA) conduit insertion of Medtronic Freestyle\u00ae porcine valve (MFV) or pulmonary allograft valve (PAV) in adult patients with congenital heart disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Retrospective medical record review of consecutive RV-to-PA conduit insertion, using either PAV or MFV from 1991 to 2017. Perioperative data and clinic reports were collected. Cause and date of death were obtained from the Australian National Death Index to obtain survival function.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>In total, 232 patients (median age 31.5\u2009years, interquartile range 25\u201341\u2009years) underwent RV-to-PA conduit insertion (PAV = 84 and MFV = 148) and were eligible for inclusion [63.8% tetralogy of Fallot (TOF); 11.6% congenital pulmonary stenosis (PS); 24.6% other diagnoses]. The overall median follow-up time was 9.1\u2009years (interquartile range 5.3\u201312.6\u2009years). The mean gradient was 11.8\u2009\u00b1\u20097.1\u2009mmHg in PAV and 16.6\u2009\u00b1\u20099.6\u2009mmHg in MFV patients. Congenital PS patients had 100% survival at 20\u2009years, TOF patients at 5, 10, 15 and 20\u2009years had 99%, 97%, 96% and 96% survival, respectively. Patients with other primary diagnoses at 5, 10, 15 and 20\u2009years had 93%, 91%, 87% and 87% respectively. Freedom from reintervention did not differ significantly at 5 and 10\u2009years between pulmonary allograft (98.6%, 98.6%) and Freestyle\u00ae porcine bioprosthesis (97.5%, 93%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Both valves perform equally well with regard to patients\u2019 freedom from reoperation, although transvalvular gradient was higher for Freestyle\u00ae patients. Congenital PS and TOF patients had better survival than patients with other primary diagnoses.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezab148","type":"journal-article","created":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T23:13:49Z","timestamp":1614813229000},"page":"939-946","source":"Crossref","is-referenced-by-count":6,"title":["Long-term outcomes of right ventricle-to-pulmonary artery conduit insertion in adults with congenital heart disease: survival analysis by National Death Index"],"prefix":"10.1093","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8162-7099","authenticated-orcid":false,"given":"Amalan","family":"Thuraisingam","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Skillington","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, VIC, Australia"},{"name":"Department of Cardiothoracic Surgery, Melbourne Private Hospital, Parkville, VIC, Australia"},{"name":"Department of Cardiothoracic Surgery, Epworth Hospital, Richmond, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Ludhani","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4264-3277","authenticated-orcid":false,"given":"Pasangi Madhuka","family":"Wijayarathne","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6915-2040","authenticated-orcid":false,"given":"Samuel","family":"Menahem","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Epworth and Melbourne Private Hospital, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Larobina","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, VIC, Australia"},{"name":"Department of Cardiothoracic Surgery, Melbourne Private Hospital, Parkville, VIC, Australia"},{"name":"Department of Cardiothoracic Surgery, Epworth Hospital, Richmond, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leeanne","family":"Grigg","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Royal Melbourne Hospital, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2240-130X","authenticated-orcid":false,"given":"Will","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Epworth and Melbourne Private Hospital, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,3,29]]},"reference":[{"key":"2021102217443617200_ezab148-B1","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The incidence of congenital heart disease","volume":"39","author":"Hoffman","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"2021102217443617200_ezab148-B2","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1016\/j.athoracsur.2014.11.058","article-title":"Mechanical prostheses for right ventricular outflow tract reconstruction: a systematic review and 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