{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T08:01:17Z","timestamp":1768723277927,"version":"3.49.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,8,15]],"date-time":"2021-08-15T00:00:00Z","timestamp":1628985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u2002<\/jats:title>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Severe left ventricular dysfunction (LVD) is associated with increased risk following coronary artery bypass grafting (CABG). Due to a dearth of reports on the choice of CABG technique in patients with LVD, this study aims to compare the outcomes of off-pump CABG (OPCAB) and conventional CABG (ONCAB) in such patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Retrospective single-centre propensity-matched analysis comparing early- and long-term outcomes of OPCAB and ONCAB in patients with severe LVD. Primary outcome was long-term all-cause mortality.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Between 2002 and 2014, a total of 1161 consecutive patients with severe LVD underwent isolated CABG [442 patients underwent OPCAB and 719 ONCAB (430 matched pairs)]. Incomplete revascularization was observed more frequently among OPCAB than ONCAB patients (35.3% vs 21.6%; P\u2009&amp;lt;\u20090.01). The overall 30-day mortality was 5% and was comparable between the matched groups [OR 0.64 (0.34\u20131.22); P\u2009=\u20090.18]. OPCAB patients had shorter median hospital stay (11 vs 12\u2009days; P\u2009=\u20090.02) and lower packed red blood cell transfusion rates [2.7 (2.21\u20133.19) vs 4.4 (3.56\u20135.24); P\u2009&amp;lt;\u20090.01]. Estimated adjusted survival was 86.0% vs 85.8%, 69.1% vs 65.5% and 59.9% vs 49.1% at 1, 5 and 10\u2009years for OPCAB and ONCAB patients, respectively (P\u2009=\u20090.99). Long-term risk of mortality was similar between groups [hazard ratio (HR) 0.94 (0.66\u20131.32); P\u2009=\u20090.7]. Incomplete revascularization was weakly associated with increased risk of long-term all-cause mortality [HR 1.33 (0.99\u20131.77); P\u2009=\u20090.05].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>OPCAB is safe and effective in patients with severe LVD. Although incomplete revascularization is more commonly observed in patients undergoing OPCAB, it is not associated with increased late mortality.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezab371","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T19:09:44Z","timestamp":1626980984000},"page":"705-713","source":"Crossref","is-referenced-by-count":13,"title":["Off-pump coronary artery bypass grafting is safe and effective in patients with severe left ventricular dysfunction"],"prefix":"10.1093","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1000-4710","authenticated-orcid":false,"given":"Mateo","family":"Marin-Cuartas","sequence":"first","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salil V","family":"Deo","sequence":"additional","affiliation":[{"name":"Department of Veterans Affairs, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5063-9959","authenticated-orcid":false,"given":"Paulina","family":"Ramirez","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Verevkin","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey","family":"Leontyev","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1046-1364","authenticated-orcid":false,"given":"Michael A","family":"Borger","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piroze M","family":"Davierwala","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"},{"name":"Division of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital, University Health Network, University of Toronto, Toronto, ON, Canada"},{"name":"Department of Surgery, University of Toronto, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,8,15]]},"reference":[{"key":"2022022016290729100_ezab371-B1","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/S1010-7940(01)00982-4","article-title":"Myocardial revascularization in patients with severe ischemic left ventricular dysfunction. 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