{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T13:31:36Z","timestamp":1770816696879,"version":"3.50.1"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T00:00:00Z","timestamp":1632268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The aim of this study was to investigate postoperative conduction disorder differences between continuous and interrupted suturing techniques for the closure of perimembranous outlet-type ventricular septal defects (VSDs) in both tetralogy of Fallot (ToF) and isolated VSD cases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Patients aged 4 years or younger who underwent VSD closure for ToF (n = 112) or isolated perimembranous outlet-type VSD (n = 73) from April 2010 to December 2018 at 3 centres were reviewed. Patients either received continuous suturing for ToF (C-ToF, n = 58) or isolated VSD (C-VSD, n = 50), or interrupted suturing for ToF (I-ToF, n = 54) or isolated VSD (I-VSD, n = 23). Cohorts did not differ in preoperative characteristics. Postoperative conduction disorder differences upon discharge and postoperative year 1 (POY1) were evaluated by electrocardiography.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The C-ToF group showed significantly shorter PQ intervals (124.0 vs 133.5 ms; P = 0.042 upon discharge, 125.3 vs 133.5 ms; P = 0.045 at POY1) and QRS durations (98.0 vs 106.2 ms; P = 0.031 upon discharge, 97.3 vs 102.5 ms; P = 0.040 at POY1) than the I-ToF group. Right bundle branch block incidence was significantly lower in the C-ToF versus I-ToF groups (56.8 vs 75.9; P = 0.045 upon discharge, 56.8 vs 75.9; P = 0.045 at POY1). Heart rates were significantly lower in the C-ToF versus I-ToF groups at POY1 (109.2 vs 119.3 bpm; P &amp;lt; 0.001). No parameters significantly differed between C-VSD and I-VSD groups. Multivariable analyses confirmed the group (C-ToF versus I-ToF) as a significant covariate in postoperative heart rate, PQ interval, QRS duration and right bundle branch block outcomes at POY1 (P = 0.013, 0.027, 0.013 and 0.014, respectively).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>A continuous suturing technique for the closure of outlet-type VSD in ToF could reduce the incidence of postoperative right bundle branch block, shorten the PQ interval and lower heart rate.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Subject collection<\/jats:title>\n                  <jats:p>110, 138, 139.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezab407","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T11:18:04Z","timestamp":1631099884000},"source":"Crossref","is-referenced-by-count":6,"title":["Conduction disorders after perimembranous ventricular septal defect closure: continuous versus interrupted suturing techniques"],"prefix":"10.1093","volume":"62","author":[{"given":"Fumiya","family":"Yoneyama","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University of Tsukuba , Tsukuba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9803-4871","authenticated-orcid":false,"given":"Hideyuki","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University of Tsukuba , Tsukuba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7163-2724","authenticated-orcid":false,"given":"Muneaki","family":"Matsubara","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University of Tsukuba , Tsukuba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9879-8289","authenticated-orcid":false,"given":"Bryan J","family":"Mathis","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University of Tsukuba , Tsukuba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Tokyo Metropolitan Children\u2019s Medical Center , Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9621-9792","authenticated-orcid":false,"given":"Masakazu","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Ibaraki Children\u2019s Hospital , Mito, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuminaga","family":"Suetsugu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Suetsugu Clinic , Tsukuba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3093-0386","authenticated-orcid":false,"given":"Kazushi","family":"Maruo","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Faculty of Medicine, University of Tsukuba , Tsukuba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8073-0633","authenticated-orcid":false,"given":"Yasuyuki","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University of Tsukuba , Tsukuba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4323-1098","authenticated-orcid":false,"given":"Yuji","family":"Hiramatsu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University of Tsukuba , Tsukuba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,9,22]]},"reference":[{"key":"2022070609163920300_ezab407-B1","doi-asserted-by":"crossref","first-page":"e006234","DOI":"10.1161\/CIRCEP.118.006234","article-title":"Prognostic significance of PR interval prolongation in adult patients with total correction of tetralogy of Fallot","volume":"11","author":"Kimura","year":"2018","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2022070609163920300_ezab407-B2","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/S0003-4975(02)03687-1","article-title":"Shallow stitching close to the rim of the ventricular septal defect eliminates injury to the right bundle branch","volume":"74","author":"Fukuda","year":"2002","journal-title":"Ann Thorac Surg"},{"key":"2022070609163920300_ezab407-B3","doi-asserted-by":"crossref","first-page":"e28735","DOI":"10.5812\/cardiovascmed.28735","article-title":"Conduction disorders in continuous versus interrupted suturing technique in ventricular septal defect surgical repair","volume":"5","author":"Gholampour-Dehaki","year":"2016","journal-title":"Res Cardiovasc Med"},{"key":"2022070609163920300_ezab407-B4","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s00246-014-1037-9","article-title":"Does surgically induced right bundle branch block really effect ventricular function in children after ventricular septal defect closure?","volume":"36","author":"Karadeniz","year":"2015","journal-title":"Pediatr Cardiol"},{"key":"2022070609163920300_ezab407-B5","doi-asserted-by":"crossref","first-page":"282","DOI":"10.5761\/atcs.oa.14-00217","article-title":"Mattress stitch\u2014a modified shallow stitching in the surgical closure of large perimembranous ventricular septal defect in infants","volume":"21","author":"Shi","year":"2015","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"2022070609163920300_ezab407-B6","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.athoracsur.2006.04.030","article-title":"Is complete heart block after surgical closure of ventricular septum defects still an issue?","volume":"82","author":"Andersen","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"2022070609163920300_ezab407-B7","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/chd.12110","article-title":"Incidence and risk factors of complete atrioventricular block after operative ventricular septal defect repair","volume":"9","author":"Siehr","year":"2014","journal-title":"Congenit Heart Dis"},{"key":"2022070609163920300_ezab407-B8","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0022-5223(19)41377-9","article-title":"The deleterious effects of surgically induced complete right bundle branch block on long-term follow-up results of closure of ventricular septal defect","volume":"74","author":"Yasui","year":"1977","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022070609163920300_ezab407-B9","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1017\/S1047951108002357","article-title":"The effects of surgically induced right bundle branch block on left ventricular function after closure of the ventricular septal defect","volume":"18","author":"Pedersen","year":"2008","journal-title":"Cardiol Young"},{"key":"2022070609163920300_ezab407-B10","doi-asserted-by":"crossref","first-page":"e418","DOI":"10.1532\/hsf.2045","article-title":"Comparison of continuous and interrupted suturing techniques in ventricular septal defect closure","volume":"21","author":"Sen","year":"2018","journal-title":"Heart Surg Forum"},{"key":"2022070609163920300_ezab407-B11","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.jacc.2008.12.013","article-title":"AHA\/ACCF\/HRS recommendations for the standardization and interpretation of the electrocardiogram: part III: intraventricular conduction disturbances: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology","volume":"53","author":"Surawicz","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"2022070609163920300_ezab407-B12","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/chd.12589","article-title":"Utility of incomplete right bundle branch block as an isolated ECG finding in children undergoing initial cardiac evaluation","volume":"13","author":"Meziab","year":"2018","journal-title":"Congenit Heart Dis"},{"key":"2022070609163920300_ezab407-B13","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ijcard.2018.06.097","article-title":"Heart rate variability is impaired in adults after closure of ventricular septal defect in childhood: a novel finding associated with right bundle branch block","volume":"274","author":"Heiberg","year":"2019","journal-title":"Int J Cardiol"}],"container-title":["European Journal of Cardio-Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ejcts\/article-pdf\/62\/1\/ezab407\/44411440\/ezab407.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ejcts\/article-pdf\/62\/1\/ezab407\/44411440\/ezab407.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T09:18:10Z","timestamp":1657099090000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejcts\/article\/doi\/10.1093\/ejcts\/ezab407\/6373863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,22]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,6,15]]}},"URL":"https:\/\/doi.org\/10.1093\/ejcts\/ezab407","relation":{},"ISSN":["1010-7940","1873-734X"],"issn-type":[{"value":"1010-7940","type":"print"},{"value":"1873-734X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,7,1]]},"published":{"date-parts":[[2021,9,22]]},"article-number":"ezab407"}}