{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:36:45Z","timestamp":1791999405303,"version":"4.4.0"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T00:00:00Z","timestamp":1633910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u2002<\/jats:title>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Acute thoracic aortic dissection and rupture (TADR) has an incidence of 5\u20137 per 100 000-person years. Today, most children with congenital heart disease (CHD) survive to become adults with congenital heart disease (ACHD). This study evaluates TADR in patients with ACHD in a large, hospitalized patient population over 11\u2009years to evaluate the incidence, risk factors and outcomes associated with TADR.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>This was a retrospective review of the Texas Inpatient Discharge Data Set from 1 January 2009 to 31 December 2019. All non-trauma discharges of patients \u226518\u2009years were included. ACHD discharges were identified by International Classification of Diseases, 9th edition (ICD-9)\/10 diagnosis codes. TADR were identified using 2 definitions: TADR1 is an ICD-9\/10 code for TADR, and TADR2 is TADR1 with an ICD-9\/10 procedure code for aortic intervention. Descriptive, univariate and logistic regression statistics were used.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A total of 22 154 664 eligible discharges were identified, of which 12 584 (0.06%) were TADR1 and a subgroup of 5699 (0.03%) were TADR2. CHD was more prevalent in TADR1 (0.2% vs 0.05%; P\u2009&amp;lt;\u20090.001) and TADR2 (0.3% vs 0.04%; P\u2009&amp;lt;\u20090.001). Adjusting for known TADR risk factors, CHD had an odds ratio of 1.69 (95% confidence interval: 1.09\u20132.63; P\u2009=\u20090.020) for TADR1 and an odds ratio of 1.69 (95% confidence interval: 0.99\u20132.88; P\u2009=\u20090.056) for TADR2. No in-hospital deaths were found in patients with CHD with TADR.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>ACHD discharges had a higher frequency of TADR versus the general population (0.9\u20131.2 vs 0.3\u20130.6 per 1000 discharges). There is an indication that CHD confers an increased adjusted odds of TADR. As the ACHD population continues to grow in number as well as age, it will be important to continue to assess the risk of TADR from CHD and how traditional risk factors impact this risk.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezab416","type":"journal-article","created":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T19:12:15Z","timestamp":1631819535000},"page":"309-317","source":"Crossref","is-referenced-by-count":7,"title":["Aortic dissection and ruptures in adult congenital heart disease in Texas from 2009 to 2019"],"prefix":"10.1093","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0725-2791","authenticated-orcid":false,"given":"Andrew","family":"Well","sequence":"first","affiliation":[{"name":"Texas Center for Pediatric and Congenital Heart Disease, UT Health Austin and Dell Children\u2019s Medical Center, Austin, TX, USA"},{"name":"Department of Surgery and Perioperative Care, University of Texas at Austin Dell Medical School, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2501-3855","authenticated-orcid":false,"given":"Michelle","family":"Mizrahi","sequence":"additional","affiliation":[{"name":"Texas Center for Pediatric and Congenital Heart Disease, UT Health Austin and Dell Children\u2019s Medical Center, Austin, TX, USA"},{"name":"Department of Surgery and Perioperative Care, University of Texas at Austin Dell Medical School, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Johnson","sequence":"additional","affiliation":[{"name":"Texas Center for Pediatric and Congenital Heart Disease, UT Health Austin and Dell Children\u2019s Medical Center, Austin, TX, USA"},{"name":"Department of Pediatrics, University of Texas at Austin Dell Medical School, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanoch","family":"Patt","sequence":"additional","affiliation":[{"name":"Texas Center for Pediatric and Congenital Heart Disease, UT Health Austin and Dell Children\u2019s Medical Center, Austin, TX, USA"},{"name":"Department of Pediatrics, University of Texas at Austin Dell Medical School, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Charles D","family":"Fraser","sequence":"additional","affiliation":[{"name":"Texas Center for Pediatric and Congenital Heart Disease, UT Health Austin and Dell Children\u2019s Medical Center, Austin, TX, USA"},{"name":"Department of Surgery and Perioperative Care, University of Texas at Austin Dell Medical School, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0779-2381","authenticated-orcid":false,"given":"Carlos M","family":"Mery","sequence":"additional","affiliation":[{"name":"Texas Center for Pediatric and Congenital Heart Disease, UT Health Austin and Dell Children\u2019s Medical Center, Austin, TX, USA"},{"name":"Department of Surgery and Perioperative Care, University of Texas at Austin Dell Medical School, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziv","family":"Beckerman","sequence":"additional","affiliation":[{"name":"Texas Center for Pediatric and Congenital Heart Disease, UT Health Austin and Dell Children\u2019s Medical Center, Austin, TX, USA"},{"name":"Department of Surgery and Perioperative Care, University of Texas at Austin Dell Medical School, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,10,11]]},"reference":[{"key":"2022012513094153400_ezab416-B1","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.jvs.2007.07.017","article-title":"Thoracic 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