{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:43:39Z","timestamp":1785422619736,"version":"3.56.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T00:00:00Z","timestamp":1636329600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Deutsche Forschungsgemeinschaft (DFG, German Research Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Transposition of the great arteries with ventricular septal defect (VSD) and left ventricular outflow tract obstruction (LVOTO) is a rare malformation. Our objective was to report on management and results of the cohort with non-committed VSD from a national registry for congenital heart disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Multicentre data were screened in the German National Registry for Congenital Heart Defects (Berlin, Germany) for repairs of transposition of the great arteries\u2013VSD\u2013LVOTO. A subgroup of patients with a remote\/non-committed VSD was identified. End points included survival, reoperation and a composite of reoperations for LVOTO-\/VSD- or baffle-related problem.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>N\u2009=\u200947 patients were identified treated in 14 different national centres between 1984 and 2020. The mean age was 14 (standard deviation 9) months, ranging from 7\u2009days to 9.5\u2009years. Nine patients (19%) were treated as neonates, 21 (45%) as infants and 17 children (36%) beyond the age of 1 year. Survival was &amp;gt;90% (80\u2013100%) at 20\u2009years. Freedom from any reoperation was 30% (10\u201350%) at 20\u2009years. Freedom from the composite end point was 72% (50\u201390%) at 20\u2009years. Patients after Rastelli underwent more reoperations compared to those without intraventricular baffle (freedom from reoperation 14% vs 50%, P\u2009=\u20090.1). The rates of the composite end point were similar when comparing Rastelli to other techniques (63% vs 83%, P\u2009=\u20090.32).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The Rastelli operation yields robust results in the setting of non-committed VSD. Late results after neonatal arterial switch operation are outstanding. If LVOTO is not resectable and neonatal arterial switch operation suboptimal, interim palliation does not negatively impact outcome, patients can be safely delayed to beyond 1 year of age.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezab477","type":"journal-article","created":{"date-parts":[[2021,10,16]],"date-time":"2021-10-16T11:32:22Z","timestamp":1634383942000},"page":"1043-1053","source":"Crossref","is-referenced-by-count":2,"title":["Transposition of great arteries with left outflow tract obstruction and non-committed VSD: surgical management and late results"],"prefix":"10.1093","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0985-9650","authenticated-orcid":false,"given":"Fabian A","family":"Kari","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Freiburg, Bad Krozingen, Germany"},{"name":"Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Uzdenov","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Freiburg, Bad Krozingen, Germany"},{"name":"Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Kroll","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Freiburg, Bad Krozingen, Germany"},{"name":"Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Bohnens","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Freiburg, Bad Krozingen, Germany"},{"name":"Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Stiller","sequence":"additional","affiliation":[{"name":"Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"},{"name":"Department of Congenital Heart Disease and Pediatric Cardiology, University Heart Center Freiburg, Bad Krozingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Bauer","sequence":"additional","affiliation":[{"name":"National Registry for Congenital Heart Defects, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rouven","family":"Kubicki","sequence":"additional","affiliation":[{"name":"Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"},{"name":"Department of Congenital Heart Disease and Pediatric Cardiology, University Heart Center Freiburg, Bad Krozingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,11,8]]},"reference":[{"key":"2022050515422050000_ezab477-B1","doi-asserted-by":"crossref","first-page":"S205","DOI":"10.1016\/S0003-4975(99)01282-5","article-title":"Congenital Heart Surgery Nomenclature and Database Project: transposition of the great arteries","volume":"69","author":"Jaggers","year":"2000","journal-title":"Ann Thorac Surg"},{"key":"2022050515422050000_ezab477-B2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1053\/pcsu.2001.24649","article-title":"Late results of the Rastelli operation for transposition of the great arteries","volume":"4","author":"Dearani","year":"2001","journal-title":"Sem Thorac Cardiovas Surg Pediatr Cardiac Surg Ann"},{"key":"2022050515422050000_ezab477-B3","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1161\/CIRCULATIONAHA.108.843102","article-title":"Outcomes after anatomic repair for d-transposition of the great arteries with left ventricular outflow tract obstruction","volume":"120","author":"Emani","year":"2009","journal-title":"Circulation"},{"key":"2022050515422050000_ezab477-B4","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1067\/mtc.2000.108163","article-title":"Twenty-five-year experience with Rastelli repair for transposition of the great arteries","volume":"120","author":"Kreutzer","year":"2000","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022050515422050000_ezab477-B5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1161\/01.CIR.39.1.83","article-title":"Complete repair of transposition of the great arteries with pulmonary stenosis. 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