{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T08:43:06Z","timestamp":1778575386352,"version":"3.51.4"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T00:00:00Z","timestamp":1637280000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Oesophagogastric anastomosis is a core part of oesophagectomy, and anastomotic leakage is among its main concerns. We used the oversewing technique to reinforce the anastomosis created with a circular stapler. This study investigated the use of oversewing to reduce the incidence of anastomotic leakage without increasing morbidity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>This study enrolled 1734 patients who underwent oesophagectomy for oesophageal cancer between April 2012 and December 2019. Using propensity score-matched analysis, the clinical results of postoperative complications were compared between anastomotic-oversewn and -unsewn oesophagectomies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Of the 1734 patients, 661 were included in the anastomotic-unsewn group and 661 in the anastomotic-oversewn group after propensity score matching. The clinical characteristics did not differ between the 2 groups, but the frequency of anastomotic leakage was significantly higher in the anastomotic-unsewn group than in the anastomotic-oversewn group (10.3% vs 4.7%, P\u2009&amp;lt;\u20090.001). Multivariable logistic analysis showed oversewn anastomosis and smoking history as the independent factors associated with anastomotic leakage (odds ratios, 0.399 and 2.383; P\u2009&amp;lt;\u20090.001 and P\u2009=\u20090.012, respectively). On the sub-group analysis, the relative risk for anastomotic leakage was significantly higher with unsewn than with oversewn anastomosis in patients &amp;lt;65\u2009years old, those with American Association of Anesthesiologists score II, those who had middle segment oesophageal cancer and those who have undergone the McKeown approach and cervical anastomosis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Anastomosis oversewing technique may be a practical method to reduce anastomotic leakage, especially in younger patients and those who have undergone the McKeown approach and cervical anastomosis.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezab495","type":"journal-article","created":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T19:10:37Z","timestamp":1635361837000},"page":"990-998","source":"Crossref","is-referenced-by-count":8,"title":["Anastomosis oversewing technique to prevent leakage after oesophagectomy: a propensity score-matched analysis"],"prefix":"10.1093","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4652-9466","authenticated-orcid":false,"given":"De-Hao","family":"Tu","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3334-3304","authenticated-orcid":false,"given":"Rirong","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Ping","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangning","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yixin","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,19]]},"reference":[{"key":"2022050515422272100_ezab495-B1","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1056\/NEJMsa1010705","article-title":"Trends in hospital volume and operative mortality for high-risk surgery","volume":"364","author":"Finks","year":"2011","journal-title":"N Engl J Med"},{"key":"2022050515422272100_ezab495-B2","doi-asserted-by":"crossref","first-page":"i3571","DOI":"10.1136\/bmj.i3571","article-title":"Surgeon specialization and operative mortality in United States: retrospective analysis","volume":"354","author":"Sahni","year":"2016","journal-title":"BMJ"},{"key":"2022050515422272100_ezab495-B3","first-page":"1481","article-title":"Mortality from esophagectomy for esophageal cancer across low, middle, and high-income countries: an international cohort study","volume":"47","author":"Kamarajah","year":"2021","journal-title":"Eur J 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