{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T03:02:43Z","timestamp":1772766163152,"version":"3.50.1"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T00:00:00Z","timestamp":1640217600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>We aimed to evaluate the 90-day mortality and effect of rescue or urgent coronary revascularization in children undergoing arterial switch operation for transposition of the great arteries with and without ventricular septal defect.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>The 90-day mortality, risk factors for mortality and outcome of rescue or urgent coronary revascularization were analysed using 8\u2009years of data from the Japan Cardiovascular Surgical Database. We only included patients with full data for all analyses.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A total of 1084 patients (median weight: 3.0\u2009kg; interquartile range: 2.8\u20133.3) underwent arterial switch operation at a median age of 10\u2009days (interquartile range: 7\u201314). The 90-day mortality (5.2%, n\u2009=\u200956) was \u223c1.6-fold higher than 30-day mortality (3.2%, n\u2009=\u200935). The cause was cardiac origin in 84% of non-survivors. Fifty-nine of the 1034 patients (5.7%) required extracorporeal membrane oxygenation (ECMO), with successful weaning in 44% (n\u2009=\u200926). Univariable or multivariable analyses revealed the following risk factors for mortality: body weight at operation &amp;lt;2.5\u2009kg, aortic cross-clamp time, cardiac events and ECMO (P\u2009&amp;lt;\u20090.005\u20130.001). Ventricular septal defect was not a risk factor.<\/jats:p>\n                  <jats:p>Thirteen patients (1.2%) had either rescue or urgent coronary revascularization with salvage rates of 25% (2\/8) and 100% (5\/5), respectively. Only 5 ECMO patients (8%) underwent coronary revascularization with 1 survivor.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The 90-day mortality represented perioperative outcomes better than 30-day mortality. Patients on ECMO, which extended the survival time, had 56% 90-day mortality. Coronary revascularization showed a salvaging effect, although the case number was small.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezab545","type":"journal-article","created":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T12:10:49Z","timestamp":1638965449000},"page":"797-804","source":"Crossref","is-referenced-by-count":8,"title":["Mortality analysis of arterial switch operation for transposition of the great arteries with and without ventricular septal defect"],"prefix":"10.1093","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6211-4351","authenticated-orcid":false,"given":"Soichiro","family":"Kitamura","sequence":"first","affiliation":[{"name":"Japan Cardiovascular Research Foundation, Osaka, Japan"},{"name":"National Cerebral and Cardiovascular Center, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6401-2885","authenticated-orcid":false,"given":"Hisateru","family":"Tachimori","sequence":"additional","affiliation":[{"name":"Keio University School of Medicine, Tokyo, Japan"},{"name":"The University of Tokyo, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arata","family":"Murakami","sequence":"additional","affiliation":[{"name":"Kanazawa Cardiovascular Hospital, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Kawata","sequence":"additional","affiliation":[{"name":"Osaka Women\u2019s and Children\u2019s Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajime","family":"Ichikawa","sequence":"additional","affiliation":[{"name":"National Cerebral and Cardiovascular Center, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Miyata","sequence":"additional","affiliation":[{"name":"Keio University School of Medicine, Tokyo, Japan"},{"name":"The University of Tokyo, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,12,23]]},"reference":[{"key":"2022032512420606500_ezab545-B1","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1016\/j.jtcvs.2013.01.053","article-title":"Predictors of 90-day mortality after congenital heart surgery: the first report of risk models from a Japanese database","volume":"148","author":"Miyata","year":"2014","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022032512420606500_ezab545-B2","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1093\/icvts\/ivv109","article-title":"The current trends of mortality following congenital heart surgery: the Japan Congenital Cardiovascular Surgery Database","volume":"21","author":"Hoashi","year":"2015","journal-title":"Interact CardioVasc Thorac Surg"},{"key":"2022032512420606500_ezab545-B3","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s11748-017-0841-6","article-title":"Current status of cardiovascular surgery in Japan, 2013 and 2014: a report based on the Japan Cardiovascular Surgery Database (JCVSD), 2: congenital heart surgery","volume":"66","author":"Hirata","year":"2018","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"2022032512420606500_ezab545-B4","first-page":"S1","article-title":"Congenital heart surgery Nomenclature and database project","volume":"69 (Suppl","year":"2000","journal-title":"Ann Thorac Surg"},{"key":"2022032512420606500_ezab545-B5","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1177\/2150135117745871","article-title":"Verification of data accuracy in Japan congenital cardiovascular surgery database including its postprocedural complication reports","volume":"9","author":"Takahashi","year":"2018","journal-title":"World J Pediatr Congenit Heart Surg"},{"key":"2022032512420606500_ezab545-B6","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1016\/j.athoracsur.2018.04.085","article-title":"Pediatric coronary artery bypass surgery for congenital heart disease","volume":"106","author":"Kitamura","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"2022032512420606500_ezab545-B7","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jtcvs.2019.11.146","article-title":"The influence of coronary artery anatomy on mortality after the arterial switch operation","volume":"160","author":"Fricke","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022032512420606500_ezab545-B8","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.jtcvs.2006.01.065","article-title":"The arterial switch operation in Europe for transpositions of the great arteries. 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