{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T16:42:33Z","timestamp":1776962553822,"version":"3.51.4"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:00:00Z","timestamp":1648684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The purpose of this study was to assess the safety and efficacy of direct cannulation of the ascending aorta in comparison with cannulating peripheral arteries.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>We retrospectively analysed type A dissection patients [n = 107; median (interquartile range [IQR]) age, 64 [53\u201373] years] from January 2008 to March 2018. The cohort was divided into 2 groups: direct ascending aorta cannulation (group A, n = 47; median [IQR] age, 69 [54\u201374] years; 34% female) and non-aortic cannulation (group B, n = 60; median [IQR] age, 62 [52\u201372] years; 20% female). Postoperative outcomes and long-term survival were compared.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Baseline characteristics were not significantly different between the 2 groups, except for higher creatinine in group B (median 0.9 vs 1.1, P = 0.028) and higher prevalence of dyslipidaemia in group A (58.7% vs 38.3%, P = 0.037). Overall early mortality was 12.1% (n = 13); 12.8% (n = 6) in group A and 11.7% (n = 7) in group B (P = 0.863). The incidence of stroke was 10.6% (n = 5) in group A and 6.7% (n = 4) in group B (P = 0.463). After adjusting for CPB and circulatory arrest times, there was no group difference in the length of ICU (P = 0.257) or hospital stay (P = 0.118), all-cause reoperation (P = 0.709), peak postoperative creatinine (P = 0.426) and lactate values (n = 60; P = 0.862). Overall survival at 1, 3 and 5 years was 84%, 78% and 73%, respectively, with no difference between the 2 groups after adjustment (P = 0.629).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Direct cannulation of the ascending aorta is a safe cannulation strategy for type A dissection repair, offering the opportunity for rapid arterial cannulation and antegrade perfusion.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezac207","type":"journal-article","created":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T20:10:47Z","timestamp":1648066247000},"source":"Crossref","is-referenced-by-count":10,"title":["Cannulation strategies for acute type A dissection\u2014role of central cannulation"],"prefix":"10.1093","volume":"62","author":[{"given":"Krithika","family":"Ramaprabhu","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nishant","family":"Saran","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Dearani","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Lahr","sequence":"additional","affiliation":[{"name":"Division of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0994-027X","authenticated-orcid":false,"given":"Hartzell","family":"Schaff","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Greason","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suraj","family":"Yalamuri","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chirantan","family":"Mangukia","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Temple University Hospital , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Stulak","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabor","family":"Bagameri","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Crestanello","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Pochettino","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic , Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,3,31]]},"reference":[{"key":"2022082913080887800_ezac207-B1","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jacc.2015.05.029","article-title":"Presentation, diagnosis, and outcomes of acute aortic dissection: 17-year trends 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A meta-analysis of nine clinical studies","volume":"47","author":"Ren","year":"2015","journal-title":"Eur J Cardiothorac Surg"},{"key":"2022082913080887800_ezac207-B8","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1016\/j.athoracsur.2015.12.032","article-title":"Open seldinger-guided femoral artery cannulation technique for thoracic aortic surgery","volume":"101","author":"Tsiouris","year":"2016","journal-title":"Ann Thorac Surg"},{"key":"2022082913080887800_ezac207-B9","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.jtcvs.2018.11.137","article-title":"Cannulation strategies in acute type A dissection repair: a systematic axillary artery approach","volume":"158","author":"Rosinski","year":"2019","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022082913080887800_ezac207-B10","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1510\/icvts.2009.231852","article-title":"Safety and efficacy of central cannulation through ascending aorta for type A aortic dissection","volume":"11","author":"Suzuki","year":"2010","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2022082913080887800_ezac207-B11","first-page":"36","article-title":"Compression of the true lumen by retrograde perfusion during repair of aortic dissection","volume":"26","author":"Robicsek","year":"1985","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"2022082913080887800_ezac207-B12","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.jtcvs.2008.02.089","article-title":"Evolving arch surgery using integrated antegrade selective cerebral perfusion: impact of axillary artery perfusion","volume":"136","author":"Ogino","year":"2008","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022082913080887800_ezac207-B13","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/j.athoracsur.2015.05.032","article-title":"Moderate versus deep hypothermia with unilateral selective antegrade cerebral perfusion for acute type A dissection","volume":"100","author":"Leshnower","year":"2015","journal-title":"Ann Thorac Surg"},{"key":"2022082913080887800_ezac207-B14","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jtcvs.2018.11.100","article-title":"Outcome after aortic, axillary, or femoral cannulation for acute type A aortic dissection","volume":"158","author":"Kreibich","year":"2019","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022082913080887800_ezac207-B15","article-title":"Direct axillary artery cannulation for type A dissection and impact of dissected innominate artery","author":"Ohira","year":"2021","journal-title":"Ann Thorac Surg"},{"key":"2022082913080887800_ezac207-B16","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1093\/icvts\/ivv041","article-title":"Outcome with peripheral versus central cannulation in acute type A dissection dagger","volume":"20","author":"Klotz","year":"2015","journal-title":"Interact CardioVasc Thorac Surg"},{"key":"2022082913080887800_ezac207-B17","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.jtcvs.2006.09.059","article-title":"Central cannulation is safe in acute aortic dissection repair","volume":"133","author":"Reece","year":"2007","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022082913080887800_ezac207-B18","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1016\/j.jamcollsurg.2021.08.058","article-title":"Do surgical outcomes for ascending aortic dissection vary based on arterial cannulation?","volume":"233","author":"Lemaire","year":"2021","journal-title":"J Am Coll Surg"},{"key":"2022082913080887800_ezac207-B19","doi-asserted-by":"crossref","first-page":"S282","DOI":"10.1161\/CIRCULATIONAHA.108.844480","article-title":"Comparison of ascending aorta versus femoral artery cannulation for acute aortic dissection type A","volume":"120","author":"Kamiya","year":"2009","journal-title":"Circulation"},{"key":"2022082913080887800_ezac207-B20","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1016\/S0003-4975(99)00353-7","article-title":"Surgery for acute type-A aortic dissection","volume":"67","author":"David","year":"1999","journal-title":"Ann Thorac Surg"},{"key":"2022082913080887800_ezac207-B21","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.jtcvs.2015.03.023","article-title":"The impact of surgical strategy on survival after repair of type A aortic dissection","volume":"150","author":"Lawton","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022082913080887800_ezac207-B22","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jtcvs.2015.04.038","article-title":"Acute type-A aortic dissection: to crossclamp or not to crossclamp? That is the question","volume":"150","author":"Shemin","year":"2015","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["European Journal of Cardio-Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ejcts\/article-pdf\/62\/3\/ezac207\/45612134\/ezac207.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ejcts\/article-pdf\/62\/3\/ezac207\/45612134\/ezac207.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T13:08:38Z","timestamp":1661778518000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejcts\/article\/doi\/10.1093\/ejcts\/ezac207\/6561483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,31]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,8,3]]}},"URL":"https:\/\/doi.org\/10.1093\/ejcts\/ezac207","relation":{},"ISSN":["1010-7940","1873-734X"],"issn-type":[{"value":"1010-7940","type":"print"},{"value":"1873-734X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,9,1]]},"published":{"date-parts":[[2022,3,31]]},"article-number":"ezac207"}}