{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:37:25Z","timestamp":1762079845041,"version":"3.41.2"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"European Union\u2019s Horizon 2020 research and innovation programme","award":["733203"],"award-info":[{"award-number":["733203"]}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["127\/2-1"],"award-info":[{"award-number":["127\/2-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Aortic steal is an underestimated risk factor for intraoperative spinal cord ischaemia. A negative effect on spinal cord perfusion in thoraco-abdominal aneurysm repair has been suspected if blood drains away from the cord initiated by a reversal of the arterial pressure gradient. The amount of blood and pressure loss via back-bleeding of segmental arteries and the impact of distal aortic perfusion (DaP) have not been analysed yet. The aim of our study was to quantify \u2018segmental steal\u2019 in vivo during simulated thoraco-abdominal aneurysm repair and to determine the impact of DaP on steal and spinal cord perfusion.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Ten juvenile pigs were put on cardiopulmonary bypass with DaP and visceral arteries were ligated. \u2018Segmental steal\u2019 was quantified by draining against gravity with\/without DaP. Blood volume of \u2018segmental steal\u2019 was quantified and microspheres were injected for Post mortem spinal cord perfusion analysis. \u2018Segmental steal\u2019 was quantified with\/without DaP\u2014and with stopped DaP.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Quantification revealed a significantly higher steal on cardiopulmonary bypass with DaP with a mean difference of 24(11) ml\/min. In all spinal cord segments, blood flow was diminished during steal drainage on DaP, compared to \u2018no steal\u2019. The least perfused region was the low thoracic to upper lumbar segment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>\u2018Segmental steal\u2019 is a relevant threat to spinal cord perfusion\u2014even with the utilization of DaP\u2014diminishing spinal cord perfusion. The blood volume lost by back-bleeding of segmental arteries is not to be underestimated and occlusion of segmental arteries should be considered in thoraco-abdominal aneurysm repair.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezac213","type":"journal-article","created":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T11:16:02Z","timestamp":1649934962000},"source":"Crossref","is-referenced-by-count":2,"title":["Impact of distal aortic perfusion on \u2018segmental steal\u2019 depleting spinal cord blood flow\u2014a quantitative experimental approach"],"prefix":"10.1093","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1742-5841","authenticated-orcid":false,"given":"Josephina","family":"Haunschild","sequence":"first","affiliation":[{"name":"University Department for Cardiac Surgery, Leipzig Heart Center , Leipzig, 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