{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T01:51:01Z","timestamp":1771379461349,"version":"3.50.1"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T00:00:00Z","timestamp":1653523200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100008052","name":"Fundaci\u00f3n Alfonso Martin Escudero","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008052","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Sutureless aortic valve replacement (SU-SAVR) has been associated with higher rates of permanent pacemaker (PPM) compared with conventionally implanted aortic bioprostheses. The purpose of this study was to determine the incidence, predictors and mid-term prognostic impact of PPM after Perceval (Livanova, London, UK) SU-SAVR in low-risk patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>A total of 400 consecutive low-risk (EuroSCORE II\u2009&amp;lt;\u20094%) patients without prior pacemaker who underwent surgical aortic valve replacement with the Perceval prosthesis from 2013 to 2019 in 2 centres were included. Baseline, clinical and electrocardiographic parameters, procedural characteristics and follow-up data were collected.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>PPM was required in 36 (9%) patients after SU-SAVR, with a median time between the procedure and PPM implantation of 7.5 (4.5\u201310.5) days. Older age and prior right bundle branch block (RBBB) were associated with an increased risk of PPM (P\u2009&amp;lt;\u20090.05 for all), but only baseline RBBB was found to be an independent predictor of new PPM requirement (odds ratio: 2.60, 95% confidence interval: 1.15\u20135.81; P\u2009=\u20090.022). At a median follow-up of 3.4 (2.3\u20134.5) years, there were no differences between groups in mortality (PPM: 36%, no PPM: 22%, P\u2009=\u20090.105) or heart failure rehospitalization (PPM: 25%, no PPM: 21%, P\u2009=\u20090.839).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>About 1 out of 10 low-risk patients with aortic stenosis undergoing SU-SAVR with the Perceval prosthesis required PPM implantation. Prior RBBB determined an increased risk (close to 3-fold) of PPM following the procedure. PPM was not associated with a higher risk of clinical events at 3-year follow-up.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezac307","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T23:15:49Z","timestamp":1654038949000},"source":"Crossref","is-referenced-by-count":9,"title":["Incidence, predictors and prognostic value of permanent pacemaker implantation following sutureless valve implantation in low-risk aortic stenosis patients"],"prefix":"10.1093","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1767-5963","authenticated-orcid":false,"given":"Victoria","family":"Vilalta","sequence":"first","affiliation":[{"name":"Department of Cardiology, Hospital Universitari Germans Trias i Pujol , Badalona, Spain"},{"name":"CIBER Enfermedades Cardiovasculares (CIBERCV) , Madrid, Spain"},{"name":"Department of Medicine, Universitat Aut\u00f2noma de Barcelona , Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Germ\u00e1n","family":"Cediel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Universitari Germans Trias i Pujol , Badalona, Spain"},{"name":"CIBER Enfermedades Cardiovasculares (CIBERCV) , Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siamak","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Quebec Heart & Lung Institute , Quebec, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0963-0207","authenticated-orcid":false,"given":"Helena","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Universitari Germans Trias i Pujol , Badalona, Spain"},{"name":"CIBER Enfermedades Cardiovasculares (CIBERCV) , Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitri","family":"Kalavrouziotis","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Quebec Heart & Lung Institute , Quebec, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"Resta","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Universitari Germans Trias i Pujol , Badalona, Spain"},{"name":"CIBER Enfermedades Cardiovasculares (CIBERCV) , Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Dumont","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Quebec Heart & Lung Institute , Quebec, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Voisine","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Quebec Heart & Lung Institute , Quebec, QC, 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Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9939-8949","authenticated-orcid":false,"given":"Alberto","family":"Alperi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Quebec Heart & Lung Institute , Quebec, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3044-197X","authenticated-orcid":false,"given":"Antoni","family":"Bayes-Genis","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Universitari Germans Trias i Pujol , Badalona, Spain"},{"name":"CIBER Enfermedades Cardiovasculares (CIBERCV) , Madrid, Spain"},{"name":"Department of Medicine, Universitat Aut\u00f2noma de Barcelona , Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep","family":"Rodes-Cabau","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Quebec Heart & Lung Institute , Quebec, QC, 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