{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:25:47Z","timestamp":1792787147188,"version":"4.5.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T00:00:00Z","timestamp":1654732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The incidence rate of distal stent graft-induced new entry (d-SINE) after frozen elephant trunk technique for aortic dissection remains controversial. The aim of this study was to investigate the incidence and seek the clinical and anatomical predictive factors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>This study is a retrospective multicentre evaluation of complications including d-SINE, aortic events and reintervention after the frozen elephant trunk procedure for aortic dissection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Our cohort included a total of 177 consecutive patients who underwent the frozen elephant trunk procedure for acute and chronic aortic dissection at 5 centres in Japan from May 2014 to March 2021. The incidence rate of d-SINE was 14.1% (25\/177 patients). The cumulative incidence of d-SINE was 7.1%, 12.4% and 21.4% after 12, 36 and 60\u2009months, respectively. d-SINE was not associated with mid-term survival rate. After competing risk regression analysis, onset time &amp;gt;48\u2009h (subdistribution hazard ratio, 3.80; 95% confidence interval, 1.13\u201312.79; P\u2009=\u20090.031) was detected as an independent predictor.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Awareness that there is a relatively higher incidence of d-SINE after frozen elephant trunk procedures is important. Non-hyper-acute phase was detected as an independent risk factor. Pre-emptive endovascular repair may be appropriate to protect new entry in high-risk patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezac325","type":"journal-article","created":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T13:00:48Z","timestamp":1654779648000},"source":"Crossref","is-referenced-by-count":31,"title":["Predictive factors of distal stent graft-induced new entry after frozen elephant trunk procedure for aortic dissection"],"prefix":"10.1093","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4172-2603","authenticated-orcid":false,"given":"Arudo","family":"Hiraoka","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, The Sakakibara Heart Institute of Okayama , Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2182-3060","authenticated-orcid":false,"given":"Yasunori","family":"Iida","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Saiseikai Yokohamashi Tobu Hospital , Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomokuni","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Akane-Foundation Tsuchiya General Hospital , Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chikara","family":"Ueki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Shizuoka Graduate University of Public Health , Shizuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Miyake","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Sakakibara Heart Institute of Okayama , Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makiko","family":"Mieno","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Center for Information, Jichi Medical University , Tochigi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8806-5110","authenticated-orcid":false,"given":"Homare","family":"Okamura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Nerima Hikarigaoka Hospital , Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,6,9]]},"reference":[{"key":"2022061514295346900_ezac325-B1","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1161\/CIRCULATIONAHA.110.015081","article-title":"Total arch replacement combined with stented elephant trunk implantation: a new \u201cstandard\u201d therapy for type a dissection involving repair of the aortic arch?","volume":"123","author":"Sun","year":"2011","journal-title":"Circulation"},{"key":"2022061514295346900_ezac325-B2","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.jtcvs.2009.02.041","article-title":"Is total arch replacement combined with stented elephant trunk implantation justified for patients with chronic Stanford type A aortic dissection?","volume":"138","author":"Sun","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022061514295346900_ezac325-B3","first-page":"II188","article-title":"New graft-implanting method for thoracic aortic aneurysm or dissection with a stented graft","volume":"94","author":"Kato","year":"1996","journal-title":"Circulation"},{"key":"2022061514295346900_ezac325-B4","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.jtcvs.2009.12.007","article-title":"Effects of partial thrombosis on distal aorta after repair of acute DeBakey type I aortic dissection","volume":"139","author":"Song","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022061514295346900_ezac325-B5","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1093\/ejcts\/ezs157","article-title":"Descending aortic aneurysmal changes following surgery for acute DeBakey type I aortic dissection","volume":"42","author":"Kim","year":"2012","journal-title":"Eur J Cardiothorac Surg"},{"key":"2022061514295346900_ezac325-B6","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.athoracsur.2008.11.061","article-title":"Operative strategy for acute type A aortic dissection: ascending aortic or hemiarch versus total arch replacement with frozen elephant trunk","volume":"87","author":"Uchida","year":"2009","journal-title":"Ann Thorac Surg"},{"key":"2022061514295346900_ezac325-B7","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1016\/j.jtcvs.2009.04.017","article-title":"Surgery for acute type A dissection using total arch replacement combined with stented elephant trunk implantation: experience with 107 patients","volume":"138","author":"Sun","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022061514295346900_ezac325-B8","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.jtcvs.2019.03.097","article-title":"Frozen elephant trunk does not increase incidence of paraplegia in patients with acute type A aortic dissection","volume":"159","author":"Poon","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022061514295346900_ezac325-B9","first-page":"329","article-title":"Long-term experience with the E-Vita open hybrid graft in complex thoracic aortic disease","volume":"51","author":"Jakob","year":"2017","journal-title":"Eur J Cardiothorac Surg"},{"key":"2022061514295346900_ezac325-B10","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1093\/ejcts\/ezz037","article-title":"Multicentre experience with two frozen elephant trunk prostheses in the treatment of acute aortic dissection","volume":"56","author":"Berger","year":"2019","journal-title":"Eur J Cardiothorac Surg"},{"key":"2022061514295346900_ezac325-B11","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.jtcvs.2019.02.069","article-title":"Aortic reinterventions after the frozen elephant trunk procedure","volume":"159","author":"Kreibich","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022061514295346900_ezac325-B12","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1067\/mtc.2002.120327","article-title":"Stent-graft-induced intimal injury one year after surgery","volume":"123","author":"Ninomiya","year":"2002","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022061514295346900_ezac325-B13","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.ejvs.2014.05.007","article-title":"Mid-term outcomes and aortic remodelling after thoracic endovascular repair for acute, subacute, and chronic aortic dissection: the VIRTUE Registry","volume":"48","author":"VIRTUE Registry Investigators","year":"2014","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"2022061514295346900_ezac325-B14","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.athoracsur.2016.02.001","article-title":"Distal stent graft-induced new entry: an emerging complication of endovascular treatment in aortic dissection","volume":"102","author":"Pantaleo","year":"2016","journal-title":"Ann Thorac Surg"},{"key":"2022061514295346900_ezac325-B15","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.athoracsur.2017.08.039","article-title":"The impact of distal stent graft-induced new entry on aortic remodeling of chronic type B dissection","volume":"105","author":"Huang","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"2022061514295346900_ezac325-B16","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/SLA.0000000000000585","article-title":"Retrograde aortic dissection after thoracic endovascular aortic repair","volume":"260","author":"Canaud","year":"2014","journal-title":"Ann Surg"},{"key":"2022061514295346900_ezac325-B17","doi-asserted-by":"crossref","first-page":"e004649","DOI":"10.1161\/JAHA.116.004649","article-title":"Retrograde type A aortic dissection after thoracic endovascular aortic repair: a systematic review and meta-analysis","volume":"6","author":"Chen","year":"2017","journal-title":"J Am Heart Assoc"},{"key":"2022061514295346900_ezac325-B18","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jvs.2018.04.047","article-title":"Retrograde type A dissection after thoracic endovascular aortic repair for type B aortic dissection","volume":"69","author":"Yammine","year":"2019","journal-title":"J Vasc Surg"},{"key":"2022061514295346900_ezac325-B19","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1177\/1526602816647939","article-title":"Impact of oversizing on the risk of retrograde dissection after TEVAR for acute and chronic type B dissection","volume":"23","author":"Liu","year":"2016","journal-title":"J Endovasc Ther"},{"key":"2022061514295346900_ezac325-B20","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jvs.2016.09.022","article-title":"Risk factors for stent graft-induced new entry after thoracic endovascular aortic repair for Stanford type B aortic dissection","volume":"65","author":"Jang","year":"2017","journal-title":"J Vasc Surg"},{"key":"2022061514295346900_ezac325-B21","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.jvs.2017.08.070","article-title":"Incidence and risk factors for retrograde type A dissection and stent graft-induced new entry after thoracic endovascular aortic repair","volume":"67","author":"Ma","year":"2018","journal-title":"J Vasc Surg"},{"key":"2022061514295346900_ezac325-B22","doi-asserted-by":"crossref","first-page":"14S","DOI":"10.1016\/j.jvs.2018.06.008","article-title":"Computational investigation of interaction between stent graft and aorta in retrograde type A dissection after thoracic endovascular aortic repair for type B aortic dissection","volume":"68","author":"Ma","year":"2018","journal-title":"J Vasc Surg"},{"key":"2022061514295346900_ezac325-B23","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/j.athoracsur.2020.02.017","article-title":"Distal stent graft-induced new entries after the frozen elephant trunk procedure","volume":"110","author":"Kreibich","year":"2020","journal-title":"Ann Thorac Surg"},{"key":"2022061514295346900_ezac325-B24","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.avsg.2020.03.022","article-title":"Aortic remodeling and clinical outcomes in type B aortic dissection according to the timing of thoracic endovascular aortic repair","volume":"67","author":"Lee","year":"2020","journal-title":"Ann Vasc Surg"},{"key":"2022061514295346900_ezac325-B25","doi-asserted-by":"crossref","DOI":"10.1093\/icvts\/ivab338","article-title":"Downstream thoracic endovascular aortic repair following zone 2, 100-mm stent graft frozen elephant trunk implantation","author":"Kreibich","year":"2021","journal-title":"Interact CardioVasc Thorac Surg"}],"container-title":["European Journal of Cardio-Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ejcts\/advance-article-pdf\/doi\/10.1093\/ejcts\/ezac325\/43989637\/ezac325.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ejcts\/article-pdf\/62\/1\/ezac325\/44080793\/ezac325.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ejcts\/article-pdf\/62\/1\/ezac325\/44080793\/ezac325.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T14:36:29Z","timestamp":1655303789000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejcts\/article\/doi\/10.1093\/ejcts\/ezac325\/6604743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,9]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,6,15]]}},"URL":"https:\/\/doi.org\/10.1093\/ejcts\/ezac325","relation":{},"ISSN":["1873-734X"],"issn-type":[{"value":"1873-734X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,7,1]]},"published":{"date-parts":[[2022,6,9]]},"article-number":"ezac325"}}