{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T12:13:03Z","timestamp":1789819983555,"version":"4.0.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T00:00:00Z","timestamp":1674604800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Figure created with BioRender.com.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>Outcomes beyond 10\u2009years for David V valve-sparing aortic root replacement (VSARR) in bicuspid aortic valve (BAV) patients have yet to be explored. We investigated long-term outcomes after BAV VSARR compared to VSARR for tricuspid aortic valve (TAV) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A total of 677 patients with BAV (n\u2009=\u2009171) and TAV (n\u2009=\u2009506) underwent VSARR between 2005 and 2020 from 2 aortic centres, excluding those with dissection, endocarditis, stenosis or prior aortic valve (AV) surgery. Multivariable Cox regression compared adjusted survival over a 12-year period. Fine and Gray competing risk regression compared risk and cumulative incidence of reoperation\/reintervention. Propensity score matching created balanced groups, and landmark analysis isolated outcomes beginning 4 years postoperatively. Finally, longitudinal mixed modelling assessed AV deterioration on echocardiogram.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>No difference was observed in 12-year survival of BAV versus TAV (propensity score matching 92.0% vs 89.9%, P\u2009=\u20090.97; multivariable hazard ratio 0.76, 95% confidence interval 0.34\u20131.69, P\u2009=\u20090.51). Adjusted 12-year cumulative incidence and risk of AV and\/or proximal aorta reoperation\/reintervention were not observed to be different (15.7% BAV vs 5.7% TAV, P\u2009=\u20090.37; subdistribution hazard ratio 1.54, 95% confidence interval 0.60\u20133.94, P\u2009=\u20090.36); however, landmark analysis showed increased incidence of late reoperation\/reintervention in BAV versus TAV (11.7% vs 0.0%, P\u2009=\u20090.04). BAV was not associated with AV deterioration over time (BAV coefficient \u00b1 standard error: 0\u2009\u00b1\u20090.30, P\u2009=\u20091).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>VSARR for BAV patients has excellent 12-year survival and low reoperation\/reintervention rates, which were not observed to be different from TAV patients. However, higher incidence of reoperation\/reintervention was observed in the late years after BAV VSARR. Our study provides key information for surgical consultation of patients with bicuspid aortopathy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezad030","type":"journal-article","created":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T16:17:04Z","timestamp":1674577024000},"source":"Crossref","is-referenced-by-count":23,"title":["Bicuspid aortic valve durability with valve-sparing aortic root replacement: comparison to tricuspid valve"],"prefix":"10.1093","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1675-0116","authenticated-orcid":false,"given":"Dov","family":"Levine","sequence":"first","affiliation":[{"name":"Division of Cardiothoracic and Vascular Surgery, New York Presbyterian Hospital, Columbia University Medical Center , New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parth","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery , Department of Surgery , 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley G","family":"Leshnower","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery , Department of Surgery , Atlanta, GA, USA"},{"name":", Emory University School of Medicine , Department of Surgery , Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Kurlansky","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic and Vascular Surgery, New York Presbyterian Hospital, Columbia University Medical Center , New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig R","family":"Smith","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic and Vascular Surgery, New York Presbyterian Hospital, Columbia University Medical Center , New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward 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