{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:46:52Z","timestamp":1774572412278,"version":"3.50.1"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T00:00:00Z","timestamp":1687564800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>To examine short- and long-term outcomes of patients with moderate-to-severe aortic insufficiency (AI) undergoing either a Bentall aortic root replacement (ARR) or valve-sparing root replacement (VSRR).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>A two-centre retrospective database of patients undergoing ARR from 2004 to 2021 was reviewed. Patients &amp;lt;18\u2009years old were excluded. A total of 1527 adult patients underwent Bentall ARR (n\u2009=\u20091150, 75%) or VSRR (n\u2009=\u2009377, 25%). Propensity score matching based on preoperative comorbidities was used and 195 matched pairs were identified. Perioperative outcomes, reoperation rates, recurrence of AI and long-term survival were evaluated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>ARR patients had more concomitant ascending aortic replacement (35% vs 20%, P\u2009=\u20090.002) and shorter cardiopulmonary bypass (189 vs 233\u2009min, P\u2009&amp;lt;\u20090.0001) and aortic cross-clamp (170 vs 204\u2009min, P\u2009&amp;lt;\u20090.0001) times than the VSRR group. Postoperatively, outcomes were similar between groups, including stroke (3% vs 2%) and in-hospital mortality (1.5% vs 2.1%), all P\u2009&amp;gt;\u20090.05. Indications for and rates of reoperation (4% vs 5%, P\u2009=\u20090.62) of the aortic valve and proximal aorta were similar between ARR and VSRR groups with reoperations occurring a mean of 3.2\u2009years after initial root replacement. The ARR group had less moderate-to-severe AI than the VSRR group (1.6% vs 14%, P\u2009=\u20090.002) a mean of 3\u2009years after surgery. Ten-year survival was similar between ARR (84%) and VSRR (82%) (P\u2009=\u20090.69) groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Both ARR and VSRR can be performed with acceptable short- and long-term outcomes in patients with moderate-to-severe AI.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezad231","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T20:42:43Z","timestamp":1687639363000},"source":"Crossref","is-referenced-by-count":14,"title":["Bentall versus valve-sparing aortic root replacement for root pathology with moderate-to-severe aortic insufficiency: a propensity-matched analysis"],"prefix":"10.1093","volume":"64","author":[{"given":"Elizabeth L","family":"Norton","sequence":"first","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine , Atlanta, 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