{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:52:53Z","timestamp":1792633973710,"version":"4.5.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:00:00Z","timestamp":1698710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p\/>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>The purpose of the study is to compare the short- and long-term outcomes of the frozen elephant trunk (FET) technique based on 2 different hybrid grafts implanted from January 2007 to July 2022.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The study includes patients who underwent an elective or emergency FET procedure. Short-term, long-term mortality and freedom from thoracic endovascular aortic repair (TEVAR) were the primary end points. Analyses were carried out separately for the periods 2007\u20132012 and 2013\u20132022<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Of the 367 enrolled, 49.3% received E-Vita Open implantation and 50.7% received Thoraflex Hybrid implants. Overall mean age was 61\u2009years [standard deviation (SD)\u2009=\u200911] and 80.7% were male. The average annual volume of FET procedures was 22.7 cases\/year. Compared to E-Vita Open, patients implanted with Thoraflex Hybrid grafts were more likely to receive distal anastomosis in zone 2 (68.3% vs 11.6%, P\u2009&amp;lt;\u20090.001) with a shorter stent portion, mean\u2009=\u2009103mm (SD\u2009=\u200911.3) vs mean\u2009=\u2009149\u2009mm (SD\u2009=\u200912.7; P\u2009&amp;lt;\u20090.001) and they underwent a reduced visceral ischaemia time, mean\u2009=\u200942.5 (SD\u2009=\u200914.2) vs mean= 61.0 (SD\u2009=\u200920.2) min, P\u2009&amp;lt;\u20090.001. In the period 2013\u20132022, overall survival at 1, 2 and 5\u2009years was 74.8%, 72.5% and 63.2% for Thoraflex and 73.2%, 70.7% and 64.1% for E-Vita, without significant differences between groups (log-rank test\u2009=\u20090.01, P\u2009=\u20090.907). Overall freedom from TEVAR at 1, 2 and 5\u2009years was 66.7%, 57.6% and 39.3% for Thoraflex and 79%, 69.7% and 66% for E-Vita, with significant differences between groups (log-rank test\u2009=\u20095.28, P\u2009=\u20090.029). In a competing risk analysis adjusted for chronic\/residual aortic syndromes and stent diameter, the Thoraflex group was more likely to receive TEVAR during follow-up (subdistribution hazard ratio SHR\u2009=\u20092.12, 95% confidence interval 1.06\u20134.22).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>The FET technique addresses acute and chronic arch disease with acceptable morbidity and mortality. Downstream endovascular reinterventions are very common during follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezad364","type":"journal-article","created":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T08:03:26Z","timestamp":1699257806000},"source":"Crossref","is-referenced-by-count":23,"title":["Frozen elephant trunk technique using hybrid grafts: 15-year outcomes from a single-centre experience"],"prefix":"10.1093","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2244-2024","authenticated-orcid":false,"given":"Giacomo","family":"Murana","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0111-7123","authenticated-orcid":false,"given":"Gregorio","family":"Gliozzi","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Di Marco","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"},{"name":"Department of Experimental, Diagnostic and Specialty Medicine, DIMES, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Campanini","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Snaidero","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Nocera","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7704-0831","authenticated-orcid":false,"given":"Paola","family":"Rucci","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences, DIBINEM, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Barberio","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Leone","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Lovato","sequence":"additional","affiliation":[{"name":"Cardiovascular Radiology Unit, Department of Medical and Surgical Sciences (DIMEC), IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4298-3792","authenticated-orcid":false,"given":"Davide","family":"Pacini","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, S.Orsola Hospital, University of Bologna , Bologna, Italy"},{"name":"Department of Experimental, Diagnostic and Specialty Medicine, DIMES, University of Bologna , Bologna, 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