{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:26:11Z","timestamp":1780615571470,"version":"3.54.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The aim of this study was to analyse the indications, surgical extent and results of treatment, as well as determine the risk factors for adverse outcomes after redo arch surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Between January 1996 and December 2022, 120 patients underwent aortic arch reoperations after primary proximal aortic surgery. We retrospectively analysed perioperative data, as well as early and mid-term outcomes in these patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Indications for arch reintervention included new aortic aneurysm in 34 patients (28.3%), expanding post-dissection aneurysm in 36 (30.0%), aortic graft infection in 39 (32.5%) and new aortic dissection in 9 cases. Two patients underwent reoperation due to iatrogenic complications. Thirty-one patients (25.8%) had concomitant endocarditis. In-hospital and 30-day mortality rates were 11.7% and 15.0%, respectively. Stroke was observed in 11 (9.2%) and paraplegia in 1 patient. Prior surgery due to aneurysm [odds ratio 4.5; 95% confidence interval (CI) 1.4\u201317.3] and critical preoperative state (odds ratio 5.9; 95% CI 1.5\u201323.7) were independent predictors of 30-day mortality. Overall 1- and 5-year survival was 65.8\u2009\u00b1\u20098.8% and 51.2\u2009\u00b1\u200910.6%, respectively. Diabetes mellitus (hazard ratio 2.4; 95% CI 1.0\u20135.1) and peripheral arterial disease (hazard ratio 4.7; 95% CI 1.1\u201314.3) were independent predictors of late death. The cumulative incidence of reoperations was 12.6% (95% CI 6.7\u201320.4%) at 5\u2009years. Accounting for mortality as a competing event, connective tissue disorders (subdistribution hazard ratio 4.5; 95% CI 1.6\u201315.7) and interval between primary and redo surgery (subdistribution hazard ratio 1.04; 95% CI 1.02\u20131.06) were independent predictors of reoperations after redo arch surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Despite being technically demanding, aortic arch reoperations are feasible and can be performed with acceptable results.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezad419","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T20:46:24Z","timestamp":1702932384000},"source":"Crossref","is-referenced-by-count":15,"title":["Aortic arch redo surgery: early and mid-term outcomes in 120 patients"],"prefix":"10.1093","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5579-9345","authenticated-orcid":false,"given":"Zara","family":"Dietze","sequence":"first","affiliation":[{"name":"University Department of Cardiac Surgery, Leipzig Heart Center , Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5555-9616","authenticated-orcid":false,"given":"Jagdip","family":"Kang","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Leipzig Heart Center , Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khadzhimurad","family":"Madomegov","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Leipzig Heart Center , Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8224-2390","authenticated-orcid":false,"given":"Christian 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