{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T18:42:43Z","timestamp":1769020963905,"version":"3.49.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>This study aimed to evaluate the short-\/mid-term outcome of patients with complex dextro (d)-\/levo (l)-transposition of the great arteries (TGA), ventricular septal defect and left ventricular outflow tract obstructions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>A single-centre, retrospective review of all complex dextro-TGA (n\u2009=\u200985) and levo-TGA (n\u2009=\u200922) patients undergoing different surgeries [Arterial switch operation + left ventricular outflow tract obstruction-resection (ASO-R), half-turned truncal switch\/Mair (HTTS), Nikaidoh and Rastelli] between May 1990 and September 2022 was performed. Groups were analysed using Kruskal\u2013Wallis test with post hoc pairwise comparison and Kaplan\u2013Meier time-to-event models.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A total of 107 patients [ASO-R (n\u2009=\u200920), HTTS (n\u2009=\u200923), Nikaidoh (n\u2009=\u200921), Rastelli (n\u2009=\u200943)] were included, with a median age of 1.0\u2009year (0.5\u20132.5) and surgical repair median follow-up was 3.8\u2009years (0.3\u201310.5). Groups did not differ in respect to early postoperative complications\/early mortality. Five-year overall survival curves were comparable: ASO-R 78.9% (53.2\u201391.5), HTTS 75.3% (46.8\u201389.9), Nikaidoh 85% (60.4\u201394.9) and Rastelli 83.9% (67.5\u201392.5), P\u2009=\u20090.9. Highest rates of right ventricular outflow tract (RVOT) reinterventions [33.3% and 32.6% (P\u2009=\u20090.04)] and reoperations [28.6% and 32.6% (P\u2009=\u20090.02)] occurred after Nikaidoh and Rastelli procedures. However, overall freedom from RVOT reinterventions and RVOT reoperations at 5\u2009years did not differ statistically significantly between the groups (ASO-R, HTTS, Nikaidoh and Rastelli): 94.4% (66.6\u201399.2), 69.1% (25.4\u201390.5), 67.8% (34\u201386.9), 64.4% (44.6\u201378.7), P\u2009=\u20090.2, and 90.0% (65.6\u201397.4), 91% (50.8\u201398.7), 65.3% (32.0\u201385.3) and 67.0% (47.4\u201380.6), P\u2009=\u20090.3.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Surgical repair of complex dextro-\/levo-TGA can be performed with satisfying early\/mid-term survival. RVOT reinterventions\/reoperations were frequent, with highest rates after Nikaidoh and Rastelli procedures. Left ventricular outflow tract obstruction reoperations were rare with zero events after Nikaidoh and HTTS procedures.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezae094","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T14:54:24Z","timestamp":1712760864000},"source":"Crossref","is-referenced-by-count":6,"title":["Repair of complex transposition of great arteries: What is the best technique to avoid outflow tract obstructions?"],"prefix":"10.1093","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0153-0364","authenticated-orcid":false,"given":"Viktoria","family":"Weixler","sequence":"first","affiliation":[{"name":"Department of Congenital Heart Surgery\u2014Pediatric Heart Surgery, Deutsches Herzzentrum der Charit\u00e9 , Berlin, Germany"},{"name":"Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Gaal","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery\u2014Pediatric Heart Surgery, Deutsches Herzzentrum der Charit\u00e9 , Berlin, Germany"},{"name":"Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6477-5727","authenticated-orcid":false,"given":"Peter","family":"Murin","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery\u2014Pediatric Heart Surgery, Deutsches Herzzentrum der Charit\u00e9 , Berlin, Germany"},{"name":"Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Kramer","sequence":"additional","affiliation":[{"name":"Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin , Berlin, Germany"},{"name":"Department of Congenital Heart Disease\u2014Pediatric Cardiology, Deutsches Herzzentrum der Charit\u00e9 , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Romanchenko","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery\u2014Pediatric Heart Surgery, Deutsches Herzzentrum der Charit\u00e9 , Berlin, Germany"},{"name":"Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi-Young","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery\u2014Pediatric Heart Surgery, Deutsches Herzzentrum der Charit\u00e9 , Berlin, Germany"},{"name":"Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Schmitt","sequence":"additional","affiliation":[{"name":"Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin , 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