{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T21:00:25Z","timestamp":1773522025352,"version":"3.50.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>After staged reconstruction for hypoplastic left heart syndrome, the neoaortic root tends to dilate, and the incidence of significant neoaortic valve insufficiency increases with time. This study aimed to evaluate the mid-term outcomes of the neoaortic root geometries and valve function after chimney reconstruction in the Norwood procedure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Between 2013 and 2021, 20 consecutive patients who underwent chimney reconstruction during the Norwood procedure for hypoplastic left heart syndrome and its variants in our institution were enrolled. The actual diameters of the following points were measured, and Z-scores were calculated based on the normal aortic root geometries using the long axis view of echocardiography at the pre-Norwood stage and the lateral view of angiography at pre-Glenn, pre-Fontan, post-Fontan and follow-up (age 5\u20136\u2009years) stages: neoaortic valve annulus; sinus of Valsalva; sinotubular junction; and ascending aorta just proximal to the anastomosis to the aortic arch. The degree of neoaortic valve regurgitation was evaluated by echocardiography at each stage.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The median follow-up period was 3.9\u2009years. Neoaortic roots after chimney reconstruction were spared from progressive dilation over time. With growth, the conical configuration of the neoaortic roots was preserved without geometrical distortion. The Z-scores of the annulus, sinus of Valsalva, sinotubular junction and ascending aorta ranged roughly from 4 to 6, 4 to 6, 2 to 4 and 0 to 2, respectively. All neoaortic valves at each stage had mild or no regurgitation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Chimney reconstruction prevented neoaortic root dilation and avoided significant neoaortic valve regurgitation in the mid-term. These neoaortic dimensions with smooth flow profiles in the neoaorta after chimney reconstruction may have contributed to the current results. Further studies are needed to clarify the long-term outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezae103","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T23:23:20Z","timestamp":1710372200000},"source":"Crossref","is-referenced-by-count":1,"title":["Configuration of the neoaortic root after chimney reconstruction in the Norwood procedure"],"prefix":"10.1093","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6139-7805","authenticated-orcid":false,"given":"Satoshi","family":"Asada","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichiro","family":"Oda","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1634-5487","authenticated-orcid":false,"given":"Yoshinobu","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9534-4580","authenticated-orcid":false,"given":"Shuhei","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7661-0265","authenticated-orcid":false,"given":"Hisayuki","family":"Hongu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eijiro","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Nakatsuji","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Nagase","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, Children\u2019s Medical Center, Kyoto Prefectural University of Medicine , Kyoto, 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