{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T10:01:41Z","timestamp":1777543301948,"version":"3.51.4"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The goal of this multicentre retrospective cohort study was to evaluate technical success and early and late outcomes of thoracic endovascular repair (TEVAR) with grafts deployed upside down through antegrade access, to treat thoracic aortic diseases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Antegrade TEVAR operations performed between January 2010 and December 2021 were collected and analysed. Both elective and urgent procedures were included. Exclusion criteria were endografts deployed in previous or concomitant surgical or endovascular repairs.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Fourteen patients were enrolled; 13 were males (94%) with a mean age of 71\u2009years (interquartile range 62; 78). Five patients underwent urgent procedures (2 ruptured aortas and 3 symptomatic patients). Indications for treatment were 8 (57%) aneurysms\/pseudoaneurysms, 3 (21%) dissections and 3 (21%) penetrating aortic ulcers. Technical success was achieved in all procedures. Early mortality occurred in 4 (28%) cases, all urgent procedures. Median follow-up was 13\u2009months (interquartile range 1; 44). Late deaths occurred in 2 (20%) patients, both operated on in elective settings. The first died at 19\u2009months of aortic-related reintervention; the second died at 34\u2009months of a non-aortic-related cause. Two patients (14%) underwent aortic-related reinterventions for late type I endoleak. The survival rate of those having the elective procedures was 100%, 84% and 67% at 12, 24 and 36\u2009months, respectively. Freedom from reintervention was 92%, 56% and 56% at 12, 24 and 36\u2009months, respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Antegrade TEVAR can seldom be considered an alternative when traditional retrograde approach is not feasible. Despite good technical success and few access-site complications, this study demonstrates high rates of late type I endoleak and aortic-related reinterventions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezae185","type":"journal-article","created":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T16:13:43Z","timestamp":1715444023000},"source":"Crossref","is-referenced-by-count":2,"title":["Multicentre experience of antegrade thoracic endovascular aortic repair for the treatment of thoracic aortic diseases"],"prefix":"10.1093","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9825-031X","authenticated-orcid":false,"given":"Lorenzo","family":"Gibello","sequence":"first","affiliation":[{"name":"Unit of Vascular Surgery, Department of Surgical Sciences, University of Turin, AOU Citt\u00e0 della Salute e della Scienza di Torino , Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Antonello","sequence":"additional","affiliation":[{"name":"Section of Vascular and Endovascular Surgery, Department of Cardiac Thoracic, Vascular Sciences and Public Health, University of Padua , Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efrem","family":"Civilini","sequence":"additional","affiliation":[{"name":"Humanitas University Department of Biomedical Sciences, Humanitas University , Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quentin","family":"Pellenc","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Vascular Surgery, Marfan Syndrome National Referral Center, Bichat University Hospital, APHP , Paris, France"},{"name":"Vascular and Endovascular Surgery Division, La Cote HealthCare Group , Morges, VD, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4803-6566","authenticated-orcid":false,"given":"Raffaello","family":"Bellosta","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgery, Poliambulanza Foundation Hospital , Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciano","family":"Carbonari","sequence":"additional","affiliation":[{"name":"Vascular Surgery Unit, Lancisi Cardiovascular Center , Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Bonardelli","sequence":"additional","affiliation":[{"name":"Vascular Surgery, Department of Surgery, Spedali Civili University Teaching Hospital, University of Brescia School of Medicine , Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Freyrie","sequence":"additional","affiliation":[{"name":"Vascular Surgery, Department of Medicine and Surgery, University of Parma , Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Riambau","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Cardiovascular Institute, Hospital Clinic, University of Barcelona , Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Varetto","sequence":"additional","affiliation":[{"name":"Unit of Vascular Surgery, Department of Surgical Sciences, University of Turin, AOU Citt\u00e0 della Salute e della Scienza di Torino , Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Verzini","sequence":"additional","affiliation":[{"name":"Unit of Vascular Surgery, Department of Surgical Sciences, University of Turin, AOU Citt\u00e0 della Salute e della Scienza di Torino , Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,5,11]]},"reference":[{"key":"2024052610563379200_ezae185-B1","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.jacc.2018.10.086","article-title":"Endovascular versus open repair of intact descending thoracic aortic aneurysms","volume":"73","author":"Chiu","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2024052610563379200_ezae185-B2","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/j.athoracsur.2019.12.054","article-title":"Thoracic endovascular aneurysm repair trends and outcomes in over 27,000 Medicare patients for descending thoracic aneurysms","volume":"109","author":"Chen","year":"2020","journal-title":"Ann Thorac Surg"},{"key":"2024052610563379200_ezae185-B3","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.ejvs.2016.06.005","article-title":"Editor\u2019s choice\u2014Management of descending thoracic aorta diseases. 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