{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T01:10:38Z","timestamp":1788570638386,"version":"build-2803163510"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T00:00:00Z","timestamp":1724630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>In the context of postcardiotomy cardiogenic shock (PCCS) following valve replacement surgery, it may be necessary to implant a peripheral veno-arterial extracorporeal membrane oxygenation (pVA-ECMO). This procedure, however, carries a risk of prosthetic valve thrombosis. The aim of this retrospective study was to describe the incidence and outcomes of prosthetic valve thrombosis after VA-ECMO support for PCCS and to report the associated risk factors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>All consecutive adult patients who received pVA-ECMO for PCCS following a valve replacement procedure between January 2015 and October 2019 in our institution were included in this retrospective study. Outcome variables were prosthetic valve thrombosis, 30-day and hospital survival, pVA-ECMO-associated adverse events and surgery-related adverse events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>During the 4-year study period, 549 patients received pVA-ECMO for PCCS. Among them, 152 had undergone a valve replacement procedure and 9 of these developed prosthetic valve thrombosis. The incidence of valve thrombosis at 30\u2009days was 7.5\u2009\u00b1\u20092%. The cumulative incidence of prosthetic valve thrombosis was significantly lower with pVA-ECMO + intra-aortic balloon pump versus VA-ECMO alone (1.4\u2009\u00b1\u20091.4% vs 13.7\u2009\u00b1\u20094.7%, P\u2009=\u20090.021, respectively). Intra-aortic balloon pump use associated with pVA-ECMO (versus pVA-ECMO alone) was an independent protective factor against hospital death [odds ratio\u2009=\u20090.180 (0.068\u20130.478), P\u2009=\u20090.001].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>After PCCS following valve replacement surgery, peripheral femoro-femoral VA-ECMO is associated with a low risk of acute valve thrombosis especially when associated with an intra-aortic balloon pump.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezae321","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T14:06:03Z","timestamp":1724681163000},"source":"Crossref","is-referenced-by-count":4,"title":["Incidence and outcomes of prosthetic valve thrombosis during peripheral extracorporeal membrane oxygenation"],"prefix":"10.1093","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6137-1273","authenticated-orcid":false,"given":"Pichoy","family":"Danial","sequence":"first","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Sorbonne University, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris (AP-HP) , Paris,","place":["France"]},{"name":"F-CRIN, INI-CRCT , Nancy,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Zamorano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Sorbonne University, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris (AP-HP) , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aude","family":"Carillion","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Surgical Intensive Care, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris\u2014Sorbonne University , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleodoro","family":"Barreda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Sorbonne University, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris (AP-HP) , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojgan","family":"Laali","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Sorbonne University, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris (AP-HP) , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Demondion","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Sorbonne University, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris (AP-HP) , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cosimo","family":"D\u2019Alessandro","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Sorbonne University, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris (AP-HP) , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrien","family":"Bougl\u00e9","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Surgical Intensive Care, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris\u2014Sorbonne University , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Pineton de Chambrun","sequence":"additional","affiliation":[{"name":"Medical Intensive Care Unit, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris\u2014Sorbonne University , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Combes","sequence":"additional","affiliation":[{"name":"Medical Intensive Care Unit, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris\u2014Sorbonne University , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Leprince","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Institute of 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