{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T07:24:44Z","timestamp":1793258684111,"version":"4.5.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>Our goal was to determine the predictive role of the combined assessment of the vasoactive-inotropic score (VIS) and lactate levels for the prognosis of patients with postcardiotomy cardiogenic shock (PCS) requiring venoarterial extracorporeal membrane oxygenation (VA-ECMO).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The data of adult patients with PCS requiring VA-ECMO between January 2015 and December 2018 at a tertiary hospital were analysed retrospectively. The incidence of in-hospital mortality and other clinical outcomes was analysed. The associations of the VIS and the lactate concentration and in-hospital mortality were assessed using logistic regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A total of 222 patients were included and divided into 4 groups according to the cut-off points of the VIS (24.3) and the lactate level (6.85\u2009mmol\/L). The in-hospital mortality rates were 37.7%, 50.7%, 54.8% and 76.5% for the 4 groups (P\u2009&amp;lt;\u20090.001), and the rates of successful weaning off VA-ECMO were 73.9%, 69%, 61.3% and 39.2%, respectively (P\u2009=\u20090.001). Groups 1 and 2 exhibited significant differences compared to group 4 in both in-hospital mortality and weaning rates (P\u2009&amp;lt;\u20090.05). There was a statistically significant difference in the incidence of multiple organ dysfunction between group 1 and group 4 (P\u2009&amp;lt;\u20090.05). Groups 1, 2 and 3 demonstrated significantly improved cumulative 30-day survival compared with group 4 (log-rank test, P\u2009&amp;lt;\u20090.05). Logistic regression analysis revealed that age, a VIS\u2009&amp;gt;\u200924.3 and lactate levels\u2009&amp;gt;\u20096.85\u2009mmol\/L were independently predictive of in-hospital mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Among patients with PCS requiring VA-ECMO, the initiation before reaching a VIS\u2009&amp;gt;\u200924.3 and lactate levels\u2009&amp;gt;\u20096.85\u2009mmol\/L was associated with improved in-hospital and 30-day outcomes, suggesting that the combined assessment of the VIS and lactate levels may be instructive for determining the initiation of VA-ECMO.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezae334","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T16:09:43Z","timestamp":1725984583000},"source":"Crossref","is-referenced-by-count":7,"title":["Combining the vasoactive-inotropic score with lactate levels to predict mortality in post-cardiotomy patients supported with venoarterial extracorporeal membrane oxygenation"],"prefix":"10.1093","volume":"66","author":[{"given":"Xiaqiu","family":"Tian","sequence":"first","affiliation":[{"name":"Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangshan","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenglong","family":"Li","sequence":"additional","affiliation":[{"name":"Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juanjuan","family":"Shao","sequence":"additional","affiliation":[{"name":"Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Jia","sequence":"additional","affiliation":[{"name":"Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotong","family":"Hou","sequence":"additional","affiliation":[{"name":"Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical 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