{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:08:54Z","timestamp":1788314934487,"version":"build-2803163510"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>We conducted this case series to evaluate the feasibility and mid-term outcomes of orthotopic aortic arch reconstruction using xenopericardial grafts to treat native aortic arch\/arch graft infection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Between 2010 and 2023, adopting a multidisciplinary approach, we treated consecutive patients with aortic arch\/arch graft infection by orthotopic branched xenopericardial roll graft replacement and tissue filling. The end points of the study were the graft reinfection and graft-related complications such as pseudoaneurysm formation, thromboembolism, graft stenosis, graft calcification and death.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The subjects were 11 patients (8 men and 3 women) with a median age of 66 [51\u201379, (interquartile range) 59.0, 70.5] years. Of the 11 patients, 7 underwent preoperative mediastinal irrigation\/negative-pressure wound treatment. The 30-day mortality was 0% (0\/11 patients), and 1 patient died in the hospital after 8\u2009months. Aorta-related death occurred in 18.2% (2\/11 patients), with both cases developing local recurrence of fungal infection. The remaining 9 patients (81.8%) remained free of reinfection. The estimated 1-, 3-, 5- and 7-year risk-adjusted survival rates were 91\u2009\u00b1\u20099%, 81\u2009\u00b1\u200912%, 58\u2009\u00b1\u200916% and 58\u2009\u00b1\u200916%, respectively. The estimated 1-, 3-, 5- and 7-year cumulative aorta-related mortality rates were 9\u2009\u00b1\u20099%, 19\u2009\u00b1\u200912%, 19\u2009\u00b1\u200912% and 19\u2009\u00b1\u200912%, respectively. Graft-related complications included branch kinking in 1 patient and graft rupture in 1 patient. There were no cases of graft-related thromboembolism or graft calcification. The median follow-up period was 45 [8\u2013101, (interquartile range) 36.5, 70.9] months. The longest follow-up period until date of the currently surviving patients is 101\u2009months.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Although the xenopericardium appeared to be vulnerable to fungal infection, based on the favourable results obtained, we consider that branched xenopericardial roll graft replacement using a multidisciplinary, staged approach may serve as a useful treatment option for aortic arch\/arch graft infection.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezae378","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T17:26:40Z","timestamp":1729704400000},"source":"Crossref","is-referenced-by-count":4,"title":["Mid-term results of a case series on branched xenopericardial roll graft replacement to treat aortic arch\/arch graft infection"],"prefix":"10.1093","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0036-2226","authenticated-orcid":false,"given":"Hiroshi","family":"Kubota","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Kyorin University , Tokyo,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidehito","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Kyorin University , Tokyo,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachito","family":"Minegishi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Kyorin University , Tokyo,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Tsuchiya","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Kyorin University , 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