{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T22:35:50Z","timestamp":1793399750051,"version":"4.5.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>Aim of the study was to analyse the impact of preoperative thoracoabdominal aneurysm diameter on the outcomes of fenestrated\/branched endografting.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Patients who underwent endovascular thoracoabdominal repair at 2 European centres (2011\u20132021) were analysed. Median diameter was calculated; the third quartile was considered a cut-off. Outcomes were compared in 2 groups based on the diameter value. Primary endpoints were technical success, spinal cord ischaemia and 30-day\/in-hospital mortality. Survival, freedom from reintervention and target visceral vessels instability were follow-up outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Out of 247 thoracoabdominal aortic aneurysms, the median diameter was 65\u2009mm, first quartile was 57\u2009mm; third quartile was 80\u2009mm, set as cut-off value. Fifty-nine (24%) patients had diameter \u226580 mm. Custom-made and off-the-shelf branched endograft were used in 160 (65%) and 87 (35%), respectively. Technical success was 93% (&amp;lt;80 mm: 91% vs \u226580 mm: 94%; P = 0.47). Twenty-three (9%) patients had spinal injury (&amp;lt;80 mm: 7% vs \u226580mm: 17%; P = 0.03). Twenty-two (9%) patients died within 30-day\/in-hospital (&amp;lt;80 mm: 7% vs \u226580 mm: 15%; P = 0.06). Multivariate analysis did not report preoperative diameter \u226580 mm as significant risk factor for primary endpoints. The median follow-up was 13 (interquartile range: 2\u201337) months and at 3-year survival and freedom from reintervention rates were 65% and 62%, respectively. After univariate and multivariate analyses, preoperative diameter \u226580 mm was considered an independent risk factor for reinterventions [hazard ratio (HR): 1.9; 95% confidence interval (CI) 1.1\u20133.6; P = 0.04], and for target visceral vessels instability (HR: 3.1; 95% CI: 1.3\u20135.1; P = 0.04), occurred in 45 (18%) cases. However, after competing risk methods, preoperative diameter did not show significance for follow-up results.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>A preoperative thoracoabdominal aortic aneurysm diameter &amp;gt;80\u2009mm has not had a direct impact on early technical and clinical outcomes. A diameter\u226580 mm is considered risk factor for reinterventions and target vessels instability is considered separately during follow-up.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ejcts\/ezae387","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T18:46:30Z","timestamp":1729795590000},"source":"Crossref","is-referenced-by-count":11,"title":["The impact of large aneurysm diameter on the outcomes of thoracoabdominal aneurysm repair by fenestrated and branched endografts"],"prefix":"10.1093","volume":"66","author":[{"given":"Enrico","family":"Gallitto","sequence":"first","affiliation":[{"name":"Vascular Surgery, University of Bologna, DIMEC , Bologna,","place":["Italy"]},{"name":"Vascular surgery unit, IRCCS Azienda Ospedaliero-universitaria di Bologna, Bologna, 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Ospedaliero-universitaria di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Stana","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, University Hospital, LMU Munich , Munich,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Logiacco","sequence":"additional","affiliation":[{"name":"Vascular Surgery, University of Bologna, DIMEC , Bologna,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlota","family":"Fernandez-Prendes","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, University Hospital, LMU Munich , Munich,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo","family":"Pini","sequence":"additional","affiliation":[{"name":"Vascular Surgery, University of Bologna, DIMEC , Bologna,","place":["Italy"]},{"name":"Vascular surgery unit, IRCCS 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