{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T15:54:01Z","timestamp":1781538841055,"version":"3.54.5"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001691","name":"KAKENHI","doi-asserted-by":"publisher","award":["21K08020"],"award-info":[{"award-number":["21K08020"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Sarcopenia and malnutrition often occur simultaneously in adults with cardiovascular diseases. Our objective was to determine the associations of preoperative sarcopenia and malnutrition with major adverse cardiac and cerebral events (MACCE) after cardiac surgery<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>We retrospectively analysed 154 consecutive patients who underwent elective cardiac surgery between January 2015 and June 2018 at two institutions in Japan. Sarcopenia and nutritional status were preoperatively assessed by bilateral psoas muscle volume index (PMVI) using CT scans and the prognostic nutritional index (PNI), respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The median age in the total cohort was 69\u2009years, and 43% were women. Within 30\u2009days after surgery, 20 patients developed in-hospital MACCE and seven patients died of any cause. Low PMVI (&amp;lt;72.25\u2009cm3\/m2) and low PNI (&amp;lt;48.15) were each independent predictors of postoperative MACCE occurrence with odds ratios (95% confidence interval) of 3.58 (1.22\u201310.53) and 3.73 (1.25\u201311.09) when adjusted for age and sex, and 3.25 (1.07\u20139.87) and 3.27 (1.08\u20139.89) when adjusted for preoperative left ventricular ejection fraction, angiotensin-converting enzyme inhibitor or angiotensin-receptor blocker, and anticoagulant. In addition, the combination of low PMVI and low PNI conferred the highest risk of in-hospital MACCE among the four groups (i.e. the low PMVI, low PNI, low PMVI\u2009+\u2009low PNI and neither low PMVI nor low PNI groups).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Preoperative low PMVI and low PNI were respectively associated with 30-day in-hospital MACCE occurrence after cardiac surgery. Notably, coexistence of these reductions further enhanced the risk of postoperative MACCE.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezae456","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T18:07:42Z","timestamp":1734458862000},"source":"Crossref","is-referenced-by-count":8,"title":["Associations of sarcopenia and malnutrition with 30-day in-hospital morbidity and mortality after cardiac surgery"],"prefix":"10.1093","volume":"67","author":[{"given":"Takahiro","family":"Abe","sequence":"first","affiliation":[{"name":"Department of Rehabilitation, Hokkaido University Hospital , Sapporo,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2141-8145","authenticated-orcid":false,"given":"Tasuku","family":"Inao","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Graduate School of Medicine, Hokkaido University , 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Ebetsu,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4149-2799","authenticated-orcid":false,"given":"Arata","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Asabu Heart and Gastrointestinal Clinic , Sapporo,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0394-0095","authenticated-orcid":false,"given":"Noriko","family":"Oyama-Manabe","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital , Sapporo,","place":["Japan"]},{"name":"Department of Radiology, Jichi Medical University Saitama Medical Center , Saitama,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6254-2225","authenticated-orcid":false,"given":"Isao","family":"Yokota","sequence":"additional","affiliation":[{"name":"Department of 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