{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T12:57:08Z","timestamp":1777035428636,"version":"3.51.4"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Single lung transplant (SLT) is an acceptable treatment modality for certain patients with end-stage lung disease. SLT occurs when two appropriate donor lungs are split between recipients (\u2018split singles\u2019) or when one donor lung is adequate for transplant and the other lung is declined (\u2018isolated single\u2019). There is a paucity of literature investigating the outcomes in patients who received an isolated SLT. This study analyses the characteristics and survival outcomes of isolated SLT recipients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>The transplant database at our institution was queried for all lung transplants between 2010 and 2021. The primary outcome of survival was assessed using Kaplan\u2013Meier curves and Cox regression modelling. Secondary outcomes were assessed using Cox regression and Fisher\u2019s exact test.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Of 759 lung transplant recipients, 164 patients underwent a split SLT, and 271 patients underwent an isolated SLT. There was no significant difference when comparing most demographic characteristics between isolated SLT and split SLT patients. Isolated SLT recipients had similar overall mortality when compared to split SLT recipients (HR 0.97, 95% CI 0.72\u20131.33, P\u2009=\u20090.87). There was no difference in postoperative need for extracorporeal membrane oxygenation (P\u2009=\u20090.209), duration of postoperative ventilation (P\u2009=\u20090.408) and length of hospitalization (P\u2009=\u20090.443).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Our analysis demonstrating similar overall survival between recipients of isolated SLT and split SLT shows that a well-selected isolated donor lung can be used safely in the appropriate recipient population. This practice allows expansion of a known scarce donor lung pool and reduction of the waitlist mortality in lung transplant candidates.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf028","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T03:02:12Z","timestamp":1738638132000},"source":"Crossref","is-referenced-by-count":2,"title":["Single lung transplantation is safe when the other lung is declined"],"prefix":"10.1093","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7948-4527","authenticated-orcid":false,"given":"Richa","family":"Asija","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery, Columbia University Irving Medical Center , New York, NY,","place":["USA"]},{"name":"Division of Surgery, Community Memorial Health Systems , Ventura, CA,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Fuller","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Costa","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexey","family":"Abramov","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harpreet","family":"Grewal","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luke","family":"Benvenuto","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Magda","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lori","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"DiMango","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilary","family":"Robbins","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan Payne","family":"Stanifer","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Sonett","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selim","family":"Arcasoy","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1678-2345","authenticated-orcid":false,"given":"Frank","family":"D\u2019Ovidio","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Columbia University Irving Medical Center , New York, NY,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Lemaitre","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Columbia University Irving Medical Center , New York, 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