{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T23:47:33Z","timestamp":1793836053524,"version":"4.6.1"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>This study aimed to evaluate the impact of intervention timing on thoracic aortic remodelling following thoracic endovascular aortic repair (TEVAR) for subacute and chronic type B aortic dissection (TBAD).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>The study included 110 patients undergoing TEVAR for TBAD at least 2\u2009weeks after onset, sourced from the Tokushukai Medical Database. The primary outcome was complete thoracic aortic remodelling (CTR) at 1\u2009year, defined as thoracic false lumen thrombosis and a false lumen diameter &amp;lt;10\u2009mm up to the level of Th10.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The 1-year CTR rate was 67.3%. CTR was strongly associated with intervention timing: 88.4% (\u22643\u2009months: n\u2009=\u200969), 57.1% (3\u201312\u2009months: n\u2009=\u200914) and 18.5% (\u226512\u2009months: n\u2009=\u200927). Receiver operating characteristic (ROC) curve analysis confirmed a 3-month cutoff for achieving CTR (area under the curve 0.857). Multivariable analysis identified interval from onset to TEVAR &amp;gt;3\u2009months (odds ratio [OR] 9.75, 95% confidence interval [CI] 2.86\u201333.28) and initial thoracic false lumen diameter (OR 1.13, 95% CI 1.02\u20131.27) as independent predictors of CTR failure. Similar trends were observed in the DeBakey IIIb subgroup, with a 3-month cutoff for achieving CTR and interval from onset to TEVAR &amp;gt;3\u2009months (OR 16.38, 95% CI 3.54\u201375.83), initial thoracic false lumen diameter (OR 1.25, 95% CI 1.00\u20131.54) and initial abdominal aortic diameters (OR 1.14, 95% CI 1.01\u20131.29) predicting CTR failure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Early TEVAR within 3\u2009months of onset is crucial for achieving complete aortic remodelling in TBAD. Therefore, early preventive TEVAR in eligible patients is recommended to optimize outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf051","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T18:49:56Z","timestamp":1739818196000},"source":"Crossref","is-referenced-by-count":5,"title":["Optimal timing of thoracic endovascular aortic repair for subacute and chronic type B aortic dissection: insights from the Tokushukai Medical Database"],"prefix":"10.1093","volume":"67","author":[{"given":"Chikara","family":"Ueki","sequence":"first","affiliation":[{"name":"Graduate School of Public Health, Shizuoka Graduate University of Public Health , Shizuoka,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomichi","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Uji-Tokushukai Medical Center , Kyoto,","place":["Japan"]},{"name":"Tokushukai Group , Osaka,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeki","family":"Ohashi","sequence":"additional","affiliation":[{"name":"Tokushukai Group , Osaka,","place":["Japan"]},{"name":"Department of Cardiovascular Surgery, Nagoya Tokushukai General Hospital , Aichi,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Higashiue","sequence":"additional","affiliation":[{"name":"Tokushukai Group , Osaka,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,2,17]]},"reference":[{"key":"2025030423585305300_ezaf051-B1","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1016\/j.jacc.2012.11.072","article-title":"Interdisciplinary expert consensus document on management of type B aortic dissection","volume":"61","author":"Fattori","year":"2013","journal-title":"J Am Coll 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