{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T21:10:13Z","timestamp":1774905013364,"version":"3.50.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:00:00Z","timestamp":1741737600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion Science","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001691","name":"KAKENHI","doi-asserted-by":"publisher","award":["17K10726"],"award-info":[{"award-number":["17K10726"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Although there has been rapid development in the field of three-dimensional morphological analyses of congenital heart disease, with the three-dimensional volume-rendered images providing visualization of the external vascular anatomy, the precise reproduction of \u2018Swiss-cheese\u2019 ventricular septum is not well established. We created three-dimensional printed models and computer graphics based on multi-slice computed tomography of patients with complex multiple ventricular septal defects for surgical decision planning of this difficult cardiac defect.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Seven patients with complex multiple ventricular septal defects were evaluated preoperatively using 3-dimensional printed models and computer graphics to plan therapeutic interventions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The three-dimensional printed models detected muscular VSDs in 9 out of 15 (60%) regions. On the other hand, 3-dimensional computer graphics detected 10 out of 15 (67%) regions. The 3-dimensional printed models and computer graphics allowed the evaluation of the muscular ventricular septal defects from both the left and right ventricular aspects of the septum.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Our preliminary experiences suggest that three-dimensional printed models and computer graphics can help plan surgery in patients with complex multiple ventricular septal defects. Three-dimensional printed models allowed surgeons to understand the three-dimensional positioning of complex multiple ventricular septal defects preoperatively. High-quality three-dimensional computer graphics provided precise information about the size, shape and localization of muscular ventricular septal defects especially from the left ventricular side.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf080","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T18:55:21Z","timestamp":1741805721000},"source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of multiple ventricular septal defects using three-dimensional reconstruction models"],"prefix":"10.1093","volume":"67","author":[{"given":"Naoki","family":"Yoshimura","sequence":"first","affiliation":[{"name":"First Department of Surgery, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaya","family":"Aoki","sequence":"additional","affiliation":[{"name":"First Department of Surgery, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8408-0965","authenticated-orcid":false,"given":"Daisuke","family":"Toritsuka","sequence":"additional","affiliation":[{"name":"First Department of Surgery, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So","family":"Motono","sequence":"additional","affiliation":[{"name":"First Department of Surgery, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saori","family":"Nagura","sequence":"additional","affiliation":[{"name":"First Department of Surgery, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshio","family":"Doi","sequence":"additional","affiliation":[{"name":"First Department of Surgery, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuaki","family":"Fukahara","sequence":"additional","affiliation":[{"name":"First Department of Surgery, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]},{"name":"Hospital Director, Imizu Municipal Hospital , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideyuki","family":"Nakaoka","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keijiro","family":"Ibuki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayaka","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Hirono","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Graduate School of Medicine, University of Toyama , Toyama,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,3,12]]},"reference":[{"key":"2025052710021136500_ezaf080-B1","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0022-5223(19)34982-7","article-title":"Surgical management of isolated multiple ventricular septal defects: logical approach in 130 cases","volume":"103","author":"Serraf","year":"1992","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025052710021136500_ezaf080-B2","first-page":"89","article-title":"Outcomes of patients undergoing surgical management of multiple ventricular septal defects","volume":"31","author":"Daley","year":"2019","journal-title":"Semin Thorac Surg"},{"key":"2025052710021136500_ezaf080-B3","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00595-015-1180-9","article-title":"Current topics in surgery for multiple ventricular septal defects","volume":"46","author":"Yoshimura","year":"2016","journal-title":"Surg Today"},{"key":"2025052710021136500_ezaf080-B4","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1111\/jocs.16289","article-title":"A review of therapeutic management of multiple ventricular septal defects","volume":"37","author":"Chowdhury","year":"2022","journal-title":"J Card Surg"},{"key":"2025052710021136500_ezaf080-B5","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1111\/jocs.16242","article-title":"A reassessment of the anatomical features of multiple ventricular septal defects","volume":"37","author":"Spicer","year":"2022","journal-title":"J Card Surg"},{"key":"2025052710021136500_ezaf080-B6","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.jtcvs.2008.08.055","article-title":"Surgical management of multiple ventricular septal defects: the role of the felt sandwich technique","volume":"137","author":"Yoshimura","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025052710021136500_ezaf080-B7","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1093\/icvts\/ivy160","article-title":"Utility of a super-flexible three-dimensional printed heart model in congenital heart surgery","volume":"27","author":"Hoashi","year":"2018","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2025052710021136500_ezaf080-B8","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1007\/s00246-017-1693-7","article-title":"Accuracy and specific value of cardiovascular 3D models in pediatric CT-angiography","volume":"38","author":"Hammon","year":"2017","journal-title":"Pediatr Cardiol"},{"key":"2025052710021136500_ezaf080-B9","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00246-016-1489-1","article-title":"Utility and scope of rapid prototyping in patients with complex muscular ventricular septal defects or double-outlet right ventricle: does it alter management decisions?","volume":"38","author":"Bhatla","year":"2017","journal-title":"Pediatr Cardiol"},{"key":"2025052710021136500_ezaf080-B10","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1053\/j.optechstcvs.2023.04.001","article-title":"Three-dimensional printing in the closure of multiple muscular ventricular septal defects","volume":"29","author":"Andugala","year":"2024","journal-title":"Operative Techniques Thorac Cardiovasc Surg"},{"key":"2025052710021136500_ezaf080-B11","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1053\/j.optechstcvs.2022.12.003","article-title":"Transatrial approach to the \u201cSwiss-cheese\u201d ventricular septal defects: sandwich technique","volume":"29","author":"Yoshimura","year":"2024","journal-title":"Operat Tech Thorac Cardiovasc Surg"},{"key":"2025052710021136500_ezaf080-B12","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1053\/j.optechstcvs.2023.12.002","article-title":"Transatrial approach to the \u201cSwiss-cheese\u201d ventricular septal defects: re-endocardialization technique","volume":"29","author":"Honjo","year":"2024","journal-title":"Operat Tech Thorac Cardiovasc Surg"},{"key":"2025052710021136500_ezaf080-B13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.4103\/picr.PICR_123_17","article-title":"Common pitfalls in statistical analysis: measures of agreement","volume":"8","author":"Ranganathan","year":"2017","journal-title":"Perspect Clin Res"},{"key":"2025052710021136500_ezaf080-B14","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1093\/ejcts\/ezx208","article-title":"Three-dimensional printed models for surgical planning of complex congenital heart defects: an international multicentre study","volume":"52","author":"Valverde","year":"2017","journal-title":"Eur J Cardiothorac Surg"},{"key":"2025052710021136500_ezaf080-B15","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.xjtc.2023.02.003","article-title":"Visualization of the complex double-outlet right ventricle anatomy using real-time three-dimensional computer graphics","volume":"18","author":"Omori","year":"2023","journal-title":"JTCVS Tech"}],"container-title":["European Journal of Cardio-Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ejcts\/advance-article-pdf\/doi\/10.1093\/ejcts\/ezaf080\/62387343\/ezaf080.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ejcts\/article-pdf\/67\/5\/ezaf080\/62387343\/ezaf080.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ejcts\/article-pdf\/67\/5\/ezaf080\/62387343\/ezaf080.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T14:46:40Z","timestamp":1748357200000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejcts\/article\/doi\/10.1093\/ejcts\/ezaf080\/8071868"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,12]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5,6]]}},"URL":"https:\/\/doi.org\/10.1093\/ejcts\/ezaf080","relation":{},"ISSN":["1010-7940","1873-734X"],"issn-type":[{"value":"1010-7940","type":"print"},{"value":"1873-734X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,5]]},"published":{"date-parts":[[2025,3,12]]},"article-number":"ezaf080"}}