{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:59:55Z","timestamp":1789664395608,"version":"4.0.1"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2022-2-2013"],"award-info":[{"award-number":["2022-2-2013"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The prevalence of mediastinal masses in large-scale populations in China has been rarely reported. During COVID19 pandemic, many incidentalomas were reported due to the large amount of chest computed tomography scan performed in emergency setting.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Retrospective analysis of emergency chest computed tomography scans (February 2020\u2013February 2021) for COVID-19 screening, including mediastinal abnormalities (excluding lymph nodes, dysplasia, pneumomediastinum and other non-mass alterations), with computed tomography features, diagnostic workup and 1\u2009year follow-up data were reviewed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Of the 40\u2009112 patients [mean age 54.5 (17.2) years; male-to-female ratio 1.02:1] screened for COVID-19, 293 (0.73%) had mediastinal masses of which 223 (0.56%) located in the anterior mediastinum. As participants aged, the prevalence tended to increase (P\u2009&amp;lt;\u20090.001). The prevalence was not different between the sexes (P\u2009=\u20090.635). An oval shape, anterior mediastinal location, and thymus involvement were the most common computed tomography characteristics. Surgery confirmed 11.3% (33 of 293) of nodal lesions, with a benign to malignant ratio of 51.4: 48.5. A computed tomography scan follow-up was conducted in 32.3% (84\/260) of the patients, and in 82.1% (69\/84) of cases the lesion was stable. Additionally, mediastinal masses were detected in 7.7% (20\/260) of elderly patients who passed away soon after their primary disease worsened.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>In Chinese COVID-19 screening chest computed tomography, the prevalence of all mediastinal masses and anterior mediastinal masses was 0.73% and 0.56%, respectively. Findings support risk-stratified management: growing\/suspicious lesions warrant intervention versus surveillance for stable masses. Standardized protocols and multidisciplinary consensus are critical.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf140","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T14:18:01Z","timestamp":1745245081000},"source":"Crossref","is-referenced-by-count":3,"title":["Incidental mediastinal masses detected on chest computed tomography scans during the COVID-19 pandemic"],"prefix":"10.1093","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6829-4469","authenticated-orcid":false,"given":"Gaojun","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peilong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3807-4043","authenticated-orcid":false,"given":"Sara","family":"Ricciardi","sequence":"additional","affiliation":[{"name":"Unit of Thoracic Surgery, San Camillo Forlanini Hospital: Azienda Ospedaliera San Camillo Forlanini , Rome,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruotian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Xuanwu Hospital Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Qian","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Cardillo","sequence":"additional","affiliation":[{"name":"Unit of Thoracic Surgery, San Camillo Forlanini Hospital: Azienda Ospedaliera San Camillo Forlanini , Rome,","place":["Italy"]},{"name":"Unicamillus International University of Health Sciences , Rome,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5173-0255","authenticated-orcid":false,"given":"Yi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,4,21]]},"reference":[{"key":"2025043019384999300_ezaf140-B1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1378\/chest.112.2.511","article-title":"Primary mediastinal tumors. 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