{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T17:56:44Z","timestamp":1780941404034,"version":"3.54.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Current preoperative counselling in neonatal cardiac surgery is mainly focused on the primary procedure. However, other factors must be considered when evaluating the surgical risk of a neonate. We aimed to develop a risk adjustment model to personalize preoperative counselling using data from the European Congenital Heart Surgeons Association Congenital Database (ECHSA-CD).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>A retrospective, multicentre analysis of the ECHSA-CD dataset was conducted, including 20\u2009687 neonates undergoing cardiac surgery between 2013 and 2022. A risk adjustment model was developed on a training set (70%) and validated on a separate cohort (30%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A model incorporating age, weight, STAT mortality category and need for cardiopulmonary bypass (CPB) demonstrated good predictive performance. Lower age (\u226410\u2009days), lower weight (&amp;lt;2.5\u2009kg), higher STAT category and need for CPB were associated with increased risk of operative mortality. The model\u2019s area under the receiver operating characteristic curve was 0.701 in the training set and 0.700 in the validation set, indicating good discrimination. Additionally, the Brier quadratic probability score was 0.08 in both datasets, indicating good calibration.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>This study underscores the importance of patient characteristics in predicting outcomes in neonatal cardiac surgery. The developed risk adjustment model can be used as a tool in preoperative counselling, decision-making and risk stratification for neonates undergoing cardiac surgery. By providing a more accurate estimate of operative mortality, this model can help families make more informed decisions about their child\u2019s care and improve the overall quality of care for neonates with congenital heart defects.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf178","type":"journal-article","created":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T16:04:18Z","timestamp":1751040258000},"source":"Crossref","is-referenced-by-count":3,"title":["Tailored preoperative assessment in neonatal cardiac surgery: a European Congenital Heart Surgeons Association study"],"prefix":"10.1093","volume":"67","author":[{"given":"Claudia","family":"Cattapan","sequence":"first","affiliation":[{"name":"Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua , Padua,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvise","family":"Guariento","sequence":"additional","affiliation":[{"name":"Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua , Padua,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey P","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Congenital Heart Center, Division of Cardiovascular Surgery, Department of Surgery, University of Florida , Gainesville, FL,","place":["USA"]},{"name":"Congenital Heart Center, Division of Cardiovascular Surgery, Department of Pediatrics, University of Florida , Gainesville, FL,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S","family":"Bleiweis","sequence":"additional","affiliation":[{"name":"Congenital Heart Center, Division of Cardiovascular Surgery, Department of Surgery, University of Florida , Gainesville, FL,","place":["USA"]},{"name":"Congenital Heart Center, Division of Cardiovascular Surgery, Department of Pediatrics, University of Florida , Gainesville, FL,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zdzislaw","family":"Tobota","sequence":"additional","affiliation":[{"name":"Pediatric Cardiothoracic Surgery, Children\u2019s Memorial Health Institute , Warsaw,","place":["Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4144-6677","authenticated-orcid":false,"given":"Bohdan","family":"Maruszewski","sequence":"additional","affiliation":[{"name":"Pediatric Cardiothoracic Surgery, Children\u2019s Memorial Health Institute , Warsaw,","place":["Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J","family":"Staffa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Boston Children\u2019s Hospital, Harvard Medical School , Boston, MA,","place":["USA"]},{"name":"Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children\u2019s Hospital, Harvard Medical School , Boston, MA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3610-6942","authenticated-orcid":false,"given":"David","family":"Zurakowski","sequence":"additional","affiliation":[{"name":"Department of Surgery, Boston Children\u2019s Hospital, Harvard Medical School , Boston, MA,","place":["USA"]},{"name":"Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children\u2019s Hospital, Harvard Medical School , Boston, MA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George E","family":"Sarris","sequence":"additional","affiliation":[{"name":"2nd Department of Pediatric and Congenital Cardiac Surgery, Mitera Children's Hospital, and Athens Heart Surgery Institute , Athens,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1829-0259","authenticated-orcid":false,"given":"Vladimiro","family":"Vida","sequence":"additional","affiliation":[{"name":"Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua , Padua,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"2025062917470691100_ezaf178-B1","doi-asserted-by":"publisher","first-page":"2204","DOI":"10.1016\/j.jtcvs.2022.06.013","article-title":"Outcomes after neonatal cardiac surgery: the impact of a dedicated neonatal cardiac program","volume":"165","author":"Goldshtrom","year":"2023","journal-title":"J Thorac Cardiovasc 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