{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T02:46:42Z","timestamp":1775098002991,"version":"3.50.1"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:00:00Z","timestamp":1760054400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Solitary fibrous tumours of the pleura (SFTP) are rare fibroblastic mesenchymal tumours with usually a benign histologic profile. However, 10%-30% will recur or metastasize. Our study aimed to determine the recurrence rate of SFTP, compare the effectiveness of 4 major risk stratification models, and analyse recurrence risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a bi-centric retrospective cohort study between 2003 and 2022 on resected SFTP. Clinical, surgical procedures and pathologic reports were examined. Patients were risk-stratified by using 4 prediction models: de Perrot, Tapias, modified Demicco, and G-score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 96 patients with 49 female (51%) and a median age of 67 years old. Median follow-up was 6 years. Sixteen patients presented recurrence\/metastasis (16.7%). The 5-years\/10-years\/15-years freedom from recurrence rates were 88.4%\/65%\/63.2%. Risk factors for recurrence were age, paraneoplastic syndrome, tumour size \u2265 10 cm, extended resection, Ki67 index \u226510%, hypercellularity, pleomorphism, necrosis, and \u2265 4 mitotic figures. The 5-years\/10-years\/15-years OS were 93.9%\/83.4%\/83.4%, respectively. During follow-up, a total of 9 patients (9.3%) died with 6 related disease death (66%). Survival was significantly worse in patients with recurrence (HR\u2009=\u200912.5 [95% CI\u2009=\u20092.58 to 61.0], P\u2009&amp;lt;\u2009.0001). Comparison of the 4 risk stratification models revealed that the modified Demicco score was the most accurate to predict recurrence (AUC= 0.83 95% CI: 0.74-0.91).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Recurrence of SFTP after surgical complete resection occurs in few patients and is associated with an increased mortality. The modified Demicco score is the most accurate to predict recurrence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf350","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T12:14:15Z","timestamp":1759925655000},"source":"Crossref","is-referenced-by-count":3,"title":["Recurrence of Solitary Fibrous Tumour of the Pleura: A 20-Years Bi-centric Study with Risk Score Comparison"],"prefix":"10.1093","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8394-8557","authenticated-orcid":false,"given":"Emilie","family":"Gagnepain","sequence":"first","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery, Grenoble Alpes University Hospital , Grenoble, 38000,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo","family":"Clermidy","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Lung and Heart-Lung Transplantation, Louis Pradel Hospital, Hospices Civils de Lyon , Lyon, 69000,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1174-7655","authenticated-orcid":false,"given":"Gabrielle","family":"Drevet","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Lung and Heart-Lung Transplantation, Louis Pradel Hospital, Hospices Civils de Lyon , Lyon, 69000,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikail","family":"Nourredine","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Hospices Civils de Lyon , Lyon, 69000,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Claire","family":"Toffart","sequence":"additional","affiliation":[{"name":"Department of Pneumology and Physiology, Grenoble Alpes University Hospital , Grenoble, 38000,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lara","family":"Chalabreysse","sequence":"additional","affiliation":[{"name":"Department of Pathology, Groupement Hospitalier Est, Hospices Civils de Lyon , Lyon, 69000,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gil","family":"Frey","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery, Grenoble Alpes University Hospital , Grenoble, 38000,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre-Yves","family":"Brichon","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery, Grenoble Alpes University Hospital , Grenoble, 38000,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Tronc","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Lung and Heart-Lung 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