{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T16:33:04Z","timestamp":1763224384116,"version":"3.45.0"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"CAMS Innovation Fund","award":["2023-I2M-C&T-B-059"],"award-info":[{"award-number":["2023-I2M-C&T-B-059"]}]},{"name":"National High Level Hospital Clinical Research Funding","award":["2025-GSP-GG-10"],"award-info":[{"award-number":["2025-GSP-GG-10"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We aimed to summarize the clinical implications and outcomes of the Ross II procedure for infants and young children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study retrospectively reviewed consecutive paediatric patients who underwent Ross II procedure from 2011 to 2022 at Fuwai Hospital. Baseline, operative, postoperative characteristics, and outcomes were summarized. Postoperative all-cause mortality was defined as the primary outcome, and reoperation as the secondary outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Ten patients who underwent the Ross II procedure were included in the final analysis, with 2 cases of late mortality and 3 cases of reoperation during a median follow-up of 36 months (range: 3.5 months to 9 years). The median age at surgery was 1.8 years (interquartile range [IQR]: 0.65 to 3.5), and the median mitral annulus diameter was 16 mm (IQR: 15 to 18). Patients who underwent the Ross II procedure experienced a prolonged postoperative course, with a median intensive care unit stay of 11.5 days (IQR: 8.5 to 19.75) and postoperative hospital stay of 24 days (IQR: 20.25 to 34.75). Mitral stenosis emerged as the predominant late complication following the Ross II procedure, affecting 80% patients, as evidenced by the increase in mean gradient 3 years postoperatively compared with discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Ross II procedure may represent a safe option for infants and young children when prosthetic valves are unavailable, despite the limited growth potential of the pulmonary autograft.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf359","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:31:12Z","timestamp":1761046272000},"source":"Crossref","is-referenced-by-count":0,"title":["Mid-term Outcomes of the Ross II Procedure in Infants and Young Children with Irreparable Mitral Disease"],"prefix":"10.1093","volume":"67","author":[{"given":"Qiyu","family":"He","sequence":"first","affiliation":[{"name":"Paediatric Cardiac Surgery Centre, National Clinical Research Centre for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College\/National Centre for Cardiovascular Diseases , Beijing 100037,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinjie","family":"Lin","sequence":"additional","affiliation":[{"name":"Paediatric Cardiac Surgery Centre, National Clinical Research Centre for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College\/National Centre for Cardiovascular Diseases , Beijing 100037,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huaping","family":"Jiang","sequence":"additional","affiliation":[{"name":"Paediatric Cardiac Surgery Centre, National Clinical Research Centre for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College\/National Centre for Cardiovascular Diseases , Beijing 100037,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"Dou","sequence":"additional","affiliation":[{"name":"Paediatric Cardiac Surgery Centre, National Clinical Research Centre for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College\/National Centre for Cardiovascular Diseases , Beijing 100037,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuze","family":"Liu","sequence":"additional","affiliation":[{"name":"Paediatric Cardiac Surgery Centre, National Clinical Research Centre for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College\/National Centre for Cardiovascular Diseases , Beijing 100037,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanbing","family":"Ma","sequence":"additional","affiliation":[{"name":"Paediatric Cardiac Surgery Centre, National Clinical Research Centre for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College\/National Centre for Cardiovascular Diseases , Beijing 100037,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Ma","sequence":"additional","affiliation":[{"name":"Paediatric Cardiac Surgery Centre, National Clinical Research Centre for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College\/National Centre for Cardiovascular Diseases , Beijing 100037,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keming","family":"Yang","sequence":"additional","affiliation":[{"name":"Paediatric Cardiac Surgery Centre, National Clinical Research Centre for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College\/National Centre for Cardiovascular Diseases , Beijing 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