{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T23:36:35Z","timestamp":1764977795495,"version":"3.46.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82472010"],"award-info":[{"award-number":["82472010"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Cardiovascular Ultrasound Innovation Team of Yunnan Province","award":["202305AS350021"],"award-info":[{"award-number":["202305AS350021"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Residual mitral regurgitation (MR) after septal myectomy increases the risk of further mitral interventions. This study aimed to identify predictors of residual MR (grade \u2265 2+) following transapical beating-heart septal myectomy (TA-BSM) in hypertrophic obstructive cardiomyopathy (HOCM) patients and to develop a predictive nomogram.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We prospectively enrolled 200 HOCM patients undergoing TA-BSM from April 2023 to March 2024, all with resting or provoked left ventricular outflow tract gradient \u2265 50 mmHg and MR \u2265 2+. Preoperative clinical and echocardiographic MV parameters were analysed. Predictors were identified via univariate and multivariate logistic regression. A nomogram was constructed and evaluated for discrimination, calibration, and clinical utility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Before discharge, 128 (64%) patients had no or mild residual MR, 65 (32.5%) moderate, and 7 (3.5%) moderate-to-severe MR. Independent predictors included atrial fibrillation, leaflet thickening \u2265\u202f5\u202fmm, annular calcification, annular anterior-posterior diameter, and annular height. The nomogram demonstrated good discrimination (area under curve (AUC) 0.879; 95% confidence interval [CI], 0.817-0.940), with favourable calibration and clinical utility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Atrial fibrillation, leaflet thickening, annular calcification, annular anterior-posterior diameter, and annular height are independent predictors of residual MR after TA-BSM. The nomogram demonstrated robust predictive performance following internal validation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf418","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T12:53:50Z","timestamp":1763211230000},"source":"Crossref","is-referenced-by-count":0,"title":["A Nomogram for Predicting Residual Mitral Regurgitation in Patients With Obstructive Hypertrohpic Cardiomyopathy Undergoing Transapical Beating-Heart Septal Myecotmy"],"prefix":"10.1093","volume":"67","author":[{"given":"Hui","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People\u2019s Republic of","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People\u2019s Republic of","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People\u2019s Republic of","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People\u2019s Republic of","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiliang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People\u2019s Republic of","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueqing","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People\u2019s Republic of","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youbin","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People\u2019s Republic of","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8335-9905","authenticated-orcid":false,"given":"Xiang","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People\u2019s Republic of","place":["China"]},{"name":"Clinical Research Center for Hypertrophic Cardiomyopathy in Hubei Province , Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People's Republic of","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5706-0811","authenticated-orcid":false,"given":"Yani","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430000, People\u2019s Republic 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