{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T15:38:46Z","timestamp":1767713926450,"version":"3.48.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"University Hospital of Saint-Etienne"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Dynamic compression bracing (DCB) systems have been proven safe and effective for non-surgical treatment of pectus carinatum (PC). This study aimed to identify potential prognostic factors for correcting PC using DCB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From 2011 to 2020, all patients treated with DCB for PC at the University Hospital of Saint-Etienne were reviewed retrospectively. The primary outcome was a \u226450% reduction in pectus height (PH) at the 6-month follow-up, measured by radiation-free imaging. Two statistical models adjusted for compliance with treatment were used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 297 patients were treated with DCB (mean age: 15.4\u2009\u00b1\u20093.9 years). A total of 42% of deformities were symmetrical. Baseline mean PH and pressure for initial correction (PIC) were 2.97\u2009\u00b1\u20091.02 cm and 6.5\u2009\u00b1\u20092.0 psi, respectively. The median total treatment duration was 13.1 months (9.2-17.9). Among the 114 (46.5%) patients with available PH data, the median decrease in PH was \u201335.8% (\u201362.4% to \u201310.0%) after 6 months of DCB, with 61 patients (53.5%) achieving a reduction \u2265 50% in PH. In multivariate analysis, only PIC (odds ratio\u2009=\u20091.34; 95% confidence interval, 1.09-1.64; P\u2009=\u2009.005) was significantly associated with PH reduction in model 1, and PIC \u2265 7.5 psi (odds ratio\u2009=\u20092.53; 95% confidence interval, 1.13-5.67; P\u2009=\u2009.024) in model 2. Patient compliance was 85.2% at 6 months. The recurrence rate was 11.3% (n\u2009=\u200926).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The PIC value appears to be a potential prognostic factor for PH reduction after 6 months of treatment with DCB. These results will be validated in an ongoing prospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial<\/jats:title>\n                    <jats:p>The study was approved by the ethical committee \u201cTerres d\u2019Ethique\u201d (IRBN902020\/CHUSTE) and registered at Clinicaltrials.gov (NCT04452721).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf444","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T13:08:10Z","timestamp":1765372090000},"source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Factors for Pectus Carinatum Treated by Dynamic Compression System: PECTUSDYN Trial"],"prefix":"10.1093","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0558-6635","authenticated-orcid":false,"given":"Lorraine","family":"Kieffer De Marco","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, University Hospital of Saint-Etienne , Saint-Priest-en-Jarez,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Filaire","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, University Hospital of Saint Etienne , Saint-Priest-en-Jarez,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6951-6468","authenticated-orcid":false,"given":"Sophie","family":"Vermersch","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, University Hospital of Saint-Etienne , Saint-Priest-en-Jarez,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9line","family":"Chapelle","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology and Clinical Research Unit, University Hospital of Saint-Etienne , Saint-Priest-en-Jarez,","place":["France"]},{"name":"INSERM UMR 1059 SAINBIOSE, Jean-Monnet University, Mines Saint-\u00c9tienne , Saint-\u00c9tienne,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnauld","family":"Garcin","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology and Clinical Research Unit, University Hospital of Saint-Etienne , Saint-Priest-en-Jarez,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Tiffet","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, University Hospital of Saint Etienne , Saint-Priest-en-Jarez,","place":["France"]},{"name":"INSERM UMR 1059 SAINBIOSE, Jean-Monnet University, Mines Saint-\u00c9tienne , Saint-\u00c9tienne,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aur\u00e9lien","family":"Scalabre","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, University Hospital of Saint-Etienne , 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