{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T01:57:07Z","timestamp":1780365427060,"version":"3.54.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Fuwai Hospital"},{"DOI":"10.13039\/501100005150","name":"Chinese Academy of Medical Sciences","doi-asserted-by":"publisher","award":["2023-GSP-GG-8"],"award-info":[{"award-number":["2023-GSP-GG-8"]}],"id":[{"id":"10.13039\/501100005150","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences","award":["2021-I2M-1-027"],"award-info":[{"award-number":["2021-I2M-1-027"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aims to evaluate the impact of concomitant aortic root replacement (ARR) on early and late outcomes in patients undergoing total arch replacement (TAR) with frozen elephant trunk (FET) for type A aortic dissection (TAAD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From January 2010 to December 2019, a total of 1155 patients were enrolled. Among them, 325 patients received concomitant ARR (with ARR group) while 830 patients did not (without ARR group). Baseline differences were adjusted using inverse probability of treatment weighting (IPTW).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After IPTW, the with ARR group still had a higher prevalence of Marfan syndrome (2.6% vs 7.3%, P\u2009=\u2009.038) and a greater proportion of patients with moderate or greater aortic insufficiency (18.1% vs 64.7%, P\u2009&amp;lt;\u2009.001). Cardiopulmonary bypass (CPB) time and aortic cross-clamp time were significantly longer in with ARR group (CPB time: 180 [151-212] vs 197 [171-236] min, P\u2009&amp;lt;\u2009.001; cross-clamp time: 100 [83-120] vs 112 [95-135] min, P\u2009&amp;lt;\u2009.001). There were no significant differences in 30-day mortality and major complications. Multivariable logistic regression analysis revealed that after adjustment for age, gender, variables with potential clinical correlation with outcomes and variables with P\u2009&amp;lt;\u2009.1 in univariable analysis, ARR was not associated with 30-day mortality (odds ratio [OR]: 0.92, 95% CI: 0.52-1.62, P\u2009=\u2009.769). There was no significant difference in overall survival (log rank: P\u2009=\u2009.258) and proximal reintervention (log rank: P\u2009=\u2009.337) in follow-up between patients in with ARR group and without ARR group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients undergoing TAR with FET for TAAD, concomitant ARR did not increase early and late postoperative mortality or morbidity. ARR can be safely performed concurrently with TAR and FET when anatomically indicated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezaf459","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T12:54:36Z","timestamp":1765976076000},"source":"Crossref","is-referenced-by-count":1,"title":["Concomitant Aortic Root Replacement in Total Arch Replacement With Frozen Elephant Trunk for Type A Aortic Dissection: A Propensity-Weighted Analysis"],"prefix":"10.1093","volume":"68","author":[{"given":"Ruojin","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100037,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanxiang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100037,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bowen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100037,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaogang","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100037,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,12,18]]},"reference":[{"key":"2026010609072895500_ezaf459-B1","doi-asserted-by":"publisher","first-page":"708","DOI":"10.21037\/cdt-22-330","article-title":"The frozen elephant trunk procedure: indications, outcomes and future directions","volume":"12","author":"Acharya","year":"2022","journal-title":"Cardiovasc Diagn Ther"},{"key":"2026010609072895500_ezaf459-B2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezae176","article-title":"The frozen elephant trunk: seeking a more definitive treatment for acute type A aortic dissection","volume":"65","author":"Papakonstantinou","year":"2024","journal-title":"Eur J Cardiothorac Surg"},{"key":"2026010609072895500_ezaf459-B3","doi-asserted-by":"publisher","first-page":"S105","DOI":"10.1016\/j.jtcvs.2014.07.098","article-title":"Frozen elephant trunk surgery in acute aortic dissection","volume":"149","author":"Di Bartolomeo","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2026010609072895500_ezaf459-B4","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1053\/j.semtcvs.2021.04.002","article-title":"Fate of preserved aortic root following acute type A aortic dissection repair","volume":"34","author":"Ellauzi","year":"2022","journal-title":"Semin Thorac Cardiovasc Surg. 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