{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T14:03:12Z","timestamp":1785247392526,"version":"3.55.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Severe mitral annular calcification (MAC) carries an increased risk of perioperative complications in patients undergoing mitral valve surgery and may be considered a prohibitive surgical risk. Cavitron ultrasonic surgical aspiration (CUSA) has been reported as a method for controlled debridement of severe MAC during mitral valve surgery; however, experience in the literature is limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We assessed 30-day and intermediate-term outcomes in 67 consecutive patients (mean age: 72 [SD 9] years; female sex: 65.7% [44\/67]) with severe MAC who underwent mitral valve repair or replacement for mitral stenosis and\/or regurgitation using CUSA from March 2021 through December 2024. Operations included isolated mitral valve replacement (41.8% [28\/67]), isolated mitral valve repair (4.5% [3\/67]), mitral and aortic valve replacement (37.3% [25\/67]), mitral valve replacement with coronary bypass (6.0% [4\/67]), and mitral and aortic valve replacement with coronary bypass (10.4% [7\/67]). Intermediate survival was estimated using the Kaplan-Meier method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mortality rate was 6.0% (4\/67), stroke was 3.0% (2\/67), and new postoperative atrial fibrillation was 29.0% (20\/67). There were no atrioventricular groove ruptures. At a median echocardiographic follow-up time of 361 days (interquartile range [IQR] 112, 671), moderate paravalvular leak occurred in 3.0% (1\/67). Mid-term all-cause mortality was 9.0% at a mean follow-up time of 42.5 (95% CI, 39.0, 46.0) months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The use of CUSA to debride severe mitral annular calcification in patients undergoing mitral valve surgery is associated with acceptable short-term morbidity and mortality and durable intermediate-term results. This technique allows surgical intervention in patients who may otherwise be deemed prohibitive surgical risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezag016","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T12:29:39Z","timestamp":1767702579000},"source":"Crossref","is-referenced-by-count":1,"title":["Early and Intermediate Outcomes of Cavitron Ultrasonic Surgical Aspiration to Treat Mitral Annular Calcification"],"prefix":"10.1093","volume":"68","author":[{"given":"Wendy","family":"Jin","sequence":"first","affiliation":[{"name":"Cardiac Surgery, Hartford Healthcare Heart and Vascular Institute , Hartford, CT, 06106,","place":["United States"]},{"name":"Cardiac Surgery, University of Connecticut School of Medicine , Farmington, CT, 06032,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabet W","family":"Hashim","sequence":"additional","affiliation":[{"name":"Cardiac Surgery, Hartford Healthcare Heart and Vascular Institute , Hartford, CT, 06106,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond G","family":"Mckay","sequence":"additional","affiliation":[{"name":"Cardiac Surgery, Hartford Healthcare Heart and Vascular Institute , Hartford, CT, 06106,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff","family":"Mather","sequence":"additional","affiliation":[{"name":"Research Administration, Hartford Hospital , Hartford, CT, 06106,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Collazo","sequence":"additional","affiliation":[{"name":"Cardiac Surgery, Hartford Healthcare Heart and Vascular Institute , Hartford, CT, 06106,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4890-9534","authenticated-orcid":false,"given":"David 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