{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T09:16:46Z","timestamp":1769937406306,"version":"3.49.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Berta-Ottenstein-Programme for Advanced Clinician Scientists, Faculty of Medicine, University of Freiburg"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare the predictive performance of the German Registry for Acute Aortic Dissection Type A (GERAADA) and new ARCH (Arch Reconstruction under Circulatory Arrest with Hypothermia) scores for in-hospital mortality in patients undergoing urgent surgery for acute type A aortic dissection (ATAAD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between January 2019 and June 2024, 192 patients were surgically treated for ATAAD at a single centre. Scores were calculated and compared. Model performance was assessed by discrimination (area under the receiver operating characteristic curve, AUC), calibration (Hosmer-Lemeshow test, calibration plots), and accuracy (Brier score, mean absolute error).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Median age was 69 years (interquartile range [IQR] 59-77), and 50.5% were male. Median GERAADA risk score was 19.3% (IQR 11.7-29.6), and actual in-hospital mortality was 14.8%. GERAADA score: AUC 0.791 (95% confidence interval [CI], 0.694-0.887), Brier score 0.118, Hosmer-Lemeshow P\u2009=\u2009.11. ARCH score: AUC 0.748 (95% CI, 0.641-0.856), Brier score 0.114, Hosmer-Lemeshow P\u2009=\u2009.17. The GERAADA score demonstrated more consistent calibration and slightly higher, not statistically significant, discrimination, while the ARCH score showed marginally better overall accuracy but underestimated mortality in higher-risk patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This is the first validation of the ARCH score specifically in patients undergoing surgery for ATAAD. Both GERAADA and ARCH scores provide an acceptable prediction of early in-hospital mortality after ATAAD surgery. The GERAADA score achieved marginally higher, but statistically non-significant, discrimination, particularly in identifying high-risk patients, whereas the ARCH score provides slightly more accurate individual risk estimates but less effective separation of survivors from non-survivors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezag026","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T12:34:20Z","timestamp":1768307660000},"source":"Crossref","is-referenced-by-count":0,"title":["Comparative Evaluation of ARCH and GERAADA Scores for Mortality Prediction in Acute Type A Aortic Dissection"],"prefix":"10.1093","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3576-433X","authenticated-orcid":false,"given":"Murat","family":"Uzdenov","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Freiburg\u2014Bad Krozingen, University Medical Center Freiburg , Freiburg 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