{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T18:54:37Z","timestamp":1768935277991,"version":"3.49.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>To reveal the prognostic outcomes of ventricular assist device (VAD) therapy with EXCOR paediatric\u00ae in Japan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Patients who underwent EXCOR paediatric implantation as a bridging therapy to transplant between August 2012 and March 2025 were enrolled. The following risk factors were evaluated for their potential to influence waitlist mortality: early surgical era, primary diagnosis, age at implantation, weight at implantation, biventricular VAD support, preoperative extracorporeal membrane oxygenation support, and preoperative mechanical ventilator support.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>The total number of 137 patients was identified. The median age and weight at the time of implantation were 15.4 months (interquartile range: 7.3\u201343.2) and 7.2\u2009kg (5.5\u201310.9), respectively. The primary diagnosis was dilated cardiomyopathy in 100 patients (72.9%), congenital heart disease in 20 patients (14.6%), and restrictive cardiomyopathy in 8 patients (5.8%). Of those, 70 (51.0%) were supported for a period exceeding one year, and the one-year survival rate was found to be 92.9%. A weight of less than 5\u2009kg at the time of Excor implantation was identified as the sole risk factor for mortality on the waitlist (p\u2009=\u20090.039, Hazard ratio: 2.43, 95% confidence interval: 1.05\u20135.68). In particular, the mortality rate of patients on the waiting list for congenital heart disease and restrictive cardiomyopathy was comparable to that of patients with dilated cardiomyopathy (p\u2009=\u20090.390, hazard ratio: 1.29, 95% confidence interval: 0.72\u20132.33).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>An analysis of JEXCOR registry data demonstrated that the prognostic outcome of bridge-to-transplant therapy with Excor paediatric was favorable in Japan.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezag033","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T12:39:15Z","timestamp":1768394355000},"source":"Crossref","is-referenced-by-count":0,"title":["Waitlist mortality in children with EXCOR support: An analysis of the Japan Excor registry"],"prefix":"10.1093","author":[{"given":"Takaya","family":"Hoashi","sequence":"first","affiliation":[{"name":"Saitama Medical University International Medical Center Department of Pediatric Cardiac Surgery, , Hidaka,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Asase","sequence":"additional","affiliation":[{"name":"National Cerebral and Cardiovascular Center Department of Transplant Medicine, , Suita,","place":["Japan"]},{"name":"Kyoto University School of Human Health Sciences, Graduate School of Medicine and Faculty of Medicine, , Kyoto,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heima","family":"Sakaguchi","sequence":"additional","affiliation":[{"name":"National Cerebral and Cardiovascular Center Department of Pediatric Cardiology, , Suita,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Narita","sequence":"additional","affiliation":[{"name":"The University of Osaka Department of Pediatrics, , Suita,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikiko","family":"Ishido","sequence":"additional","affiliation":[{"name":"Tokyo Women\u2019s Medical University Department of Pediatric Cardiology, , Tokyo,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susumu","family":"Urata","sequence":"additional","affiliation":[{"name":"National Center for Child and Development Division of Cardiology, , Tokyo,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Toda","sequence":"additional","affiliation":[{"name":"Saitama Medical University International Medical Center Department of Pediatric Cardiology, , Hidaka,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Murakami","sequence":"additional","affiliation":[{"name":"University of Tsukuba Department of Child Health, Faculty of Medicine, , Tsukuba, Ibaraki,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoichiro","family":"Hirata","sequence":"additional","affiliation":[{"name":"Kitasato University School of Medicine Department of Pediatrics, , Sagamihara,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichiro","family":"Hirata","sequence":"additional","affiliation":[{"name":"Kyushu University Hospital Department of Pediatrics, , Fukuoka,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Ono","sequence":"additional","affiliation":[{"name":"The University of Tokyo Department of Cardiovascular Surgery, Graduate School of Medicine, , Tokyo,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayoshi","family":"Ueno","sequence":"additional","affiliation":[{"name":"The University of Osaka Division of Health Sciences, , Suita,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norihide","family":"Fukushima","sequence":"additional","affiliation":[{"name":"National Cerebral and Cardiovascular Center Department of Transplant Medicine, , Suita,","place":["Japan"]},{"name":"Senri Kinran University Department of Nursing, , Suita,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,1,19]]},"container-title":["European Journal of Cardio-Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ejcts\/advance-article-pdf\/doi\/10.1093\/ejcts\/ezag033\/66464666\/ezag033.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ejcts\/advance-article-pdf\/doi\/10.1093\/ejcts\/ezag033\/66464666\/ezag033.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T04:55:13Z","timestamp":1768884913000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejcts\/advance-article\/doi\/10.1093\/ejcts\/ezag033\/8430294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,19]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/ejcts\/ezag033","relation":{},"ISSN":["1873-734X"],"issn-type":[{"value":"1873-734X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,19]]},"article-number":"ezag033"}}