{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:20:36Z","timestamp":1791868836333,"version":"4.3.4"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Data on the role of obesity in patients undergoing minimally invasive cardiac surgery are sparse, and the longitudinal observations after minimally invasive mitral valve repair (MI-MVr) in obese patients are lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective propensity-score-matched analysis compared the outcomes of MI-MVr in obese patients (body mass index [BMI] \u226530 kg\/m2), with those in individuals with normal body weight (BMI 19-25 kg\/m2), focusing on overall survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In 501 analysed matched pairs, BMI ranged 30-60 kg\/m2 in obese group and 19-24.9 kg\/m2 in normal-BMI group. There were no baseline differences among matched cohorts, except for higher incidence of hypertension (78% vs 57%, P\u2009&amp;lt;\u2009.001) and hypercholesterolaemia (35% vs 28%, P\u2009=\u2009.02) in obese patients, and slightly worse renal function. All patients received MI-MVr through right lateral mini-thoracotomy. The median total operative time (by 11 minutes) and cardiopulmonary by-pass time (by 5 minutes) were longer in obese patients (P\u2009=\u2009.001), but the cross-clamp times did not differ. There were no intergroup differences in the early complication rates or hospitalization lengths. After a median follow-up of 9.3 years, the overall survival was similar. Actuarial survival at 15 years was 59% for obese patients and 57% for those with normal BMI (log-rank, P\u2009=\u2009.38). A multivariable model identified diabetes (HR [95% CI], 1.65 [1.26-2.16], P\u2009=\u2009.0003), chronic lung disease (1.81 [1.31-2.51], P\u2009=\u2009.0004), left ventricular ejection fraction (LVEF) &amp;lt;50% (2.28 [1.78-2.93], P \u2264 .0001), and older age (1.08 [1.07-1.10], P \u2264 .0001) as independent predictors of mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Obesity alone does not influence the outcomes of MI-MVr, but diabetes, chronic lung disease, and impaired pump function do affect the overall survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezag064","type":"journal-article","created":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T12:36:59Z","timestamp":1769258219000},"source":"Crossref","is-referenced-by-count":1,"title":["Obesity Does Not Influence the Outcomes of Minimally Invasive Mitral Valve Repair for Mitral Regurgitation: A Longitudinal Analysis"],"prefix":"10.1093","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4077-1232","authenticated-orcid":false,"given":"Piotr","family":"Mazur","sequence":"first","affiliation":[{"name":"University Department of Cardiac Surgery, Leipzig Heart Center , Leipzig 04289,","place":["Germany"]},{"name":"Institute of Cardiology, Jagiellonian University Medical College , Krak\u00f3w 31-202,","place":["Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Gadelkarim","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Leipzig Heart Center , Leipzig 04289,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateo","family":"Marin-Cuartas","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Leipzig Heart Center , Leipzig 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