{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:42:38Z","timestamp":1787496158358,"version":"build-2736575974"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Patients with congenitally corrected transposition of the great arteries (ccTGA) may undergo physiologic repair, leaving the right ventricle systemic, or anatomic repair, correcting the double discordance. We compared both strategies in an international study using propensity-score matching.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients from 12 European centres, aged &amp;lt;18 years, who underwent either physiologic or anatomic repair between 1990 and 2010 were included (n\u2009=\u2009266). Patients were matched by optimal pair matching on ventricular septal defect, subpulmonary left ventricular outflow tract obstruction, \u2265mild systemic tricuspid valve regurgitation, age, and gender, resulting in a 1:1 matched cohort of 162 patients. The resulting groups were compared for long-term survival, reoperations, and function of the systemic ventricle and atrioventricular valve.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Transplant-free survival at 10 and 15 years was 87\u2009\u00b1\u20094%, 95% confidence interval (CI) [79%-95%] and 80\u2009\u00b1\u20096% [68%-93%] for the physiologic group and 85\u2009\u00b1\u20095% [78%-96%] and 85\u2009\u00b1\u20095% [78%-96%] for the anatomic group (P\u2009=\u2009.568). Freedom from cardiac reoperation at 10 and 15 years was 73\u2009\u00b1\u20096% [62%-85%] and 56\u2009\u00b1\u20098% [41%-75%] for the physiologic group and 61\u2009\u00b1\u20098% [47%-76%] and 36\u2009\u00b1\u20099% [26%-62%] for the anatomic group (P\u2009=\u2009.279). Tricuspid valve regurgitation at final follow-up was present in 57% (27\/47) vs 17% (12\/72), respectively (P\u2009&amp;lt;\u2009.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Long-term survival and reoperation rates are similar in comparable patients following physiologic and anatomic repair of ccTGA in childhood. Tricuspid valve function may deteriorate when left in the systemic position following physiologic repair. In contrast, patients with tricuspid regurgitation may benefit from anatomic repair, with improved function in the subpulmonary position.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezag148","type":"journal-article","created":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T11:37:44Z","timestamp":1775907464000},"source":"Crossref","is-referenced-by-count":2,"title":["Anatomic Versus Physiologic Repair in Congenitally Corrected Transposition: A Propensity-Matched European Multicentre Study"],"prefix":"10.1093","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7947-8637","authenticated-orcid":false,"given":"Jelena","family":"Pabst von Ohain","sequence":"first","affiliation":[{"name":"Division of Congenital Heart Surgery, University Hospital Grosshadern, Ludwig-Maximilians University , 81377 Munich,","place":["Germany"]},{"name":"Department of Congenital and Paediatric Heart Surgery, German Heart Center Munich, School of Medicine, University Hospital of the Technical University Munich , 80636 Munich,","place":["Germany"]},{"name":"Department of Congenital and Paediatric Heart Surgery, Klinikum Stuttgart , 70174 Stuttgart,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonie","family":"Arnold","sequence":"additional","affiliation":[{"name":"Division of Paediatric Cardiology, University Hospital Grosshadern, Ludwig-Maximilians University , 81377 Munich,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirolos A","family":"Jacob","sequence":"additional","affiliation":[{"name":"Department of Paediatric Cardiac Surgery, University Medical Centre Utrecht , 3584 CX Utrecht,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Barron","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Hospital for Sick Children , Toronto, ON M5G 1X8,","place":["Canada"]},{"name":"Department of Surgery, University of Toronto , Toronto, ON M5T 1P5,","place":["Canada"]},{"name":"Birmingham Children\u2019s Hospital Paediatric Cardiac Surgery, , Birmingham B4 6NH,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel E","family":"Drury","sequence":"additional","affiliation":[{"name":"Birmingham Children\u2019s Hospital Paediatric Cardiac Surgery, , Birmingham B4 6NH,","place":["United Kingdom"]},{"name":"Department of Cardiovascular Sciences, University of Birmingham , Birmingham B15 2TT,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehreen","family":"Farooqi","sequence":"additional","affiliation":[{"name":"Birmingham Children\u2019s Hospital Paediatric Cardiac Surgery, , Birmingham B4 6NH,","place":["United Kingdom"]},{"name":"Department of Cardiovascular Sciences, University of Birmingham , Birmingham B15 2TT,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktor","family":"Hraska","sequence":"additional","affiliation":[{"name":"Herma Heart Institute, Medical College of Wisconsin , Milwaukee, WI 53226,","place":["United States"]},{"name":"German Pediatric Heart Centre, Asklepios Clinic Sankt Augustin , 53757 Sankt Augustin,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boulos","family":"Asfour","sequence":"additional","affiliation":[{"name":"German Pediatric Heart Centre, Asklepios Clinic Sankt Augustin , 53757 Sankt Augustin,","place":["Germany"]},{"name":"Division of Paediatric Heart Surgery, University Hospital Bonn , 53127 Bonn,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Vergnat","sequence":"additional","affiliation":[{"name":"German Pediatric Heart Centre, Asklepios Clinic Sankt Augustin , 53757 Sankt Augustin,","place":["Germany"]},{"name":"Division of Paediatric Heart Surgery, University Hospital Bonn , 53127 Bonn,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3234-5436","authenticated-orcid":false,"given":"Alexey","family":"Arkhipov","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease, E. Meshalkin National Medical Research Center , 630055 Novosibirsk, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nataliya R","family":"Nichay","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease, E. Meshalkin National Medical Research Center , 630055 Novosibirsk, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8326-6610","authenticated-orcid":false,"given":"Emre","family":"Belli","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease, H\u00f4pital Marie Lannelongue , 92350 Les Plessis Robinson,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarrah","family":"Abdullah","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiac Surgery, Chest Diseases Hospital , 70030 Kuwait City,","place":["Kuwait"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikka P","family":"Mattila","sequence":"additional","affiliation":[{"name":"Pediatric Cardiac and Transplantation Surgery, New Children\u2019s Hospital, Helsinki University Hospital , 00290 Helsinki,","place":["Finland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heikki I","family":"Sairanen","sequence":"additional","affiliation":[{"name":"Pediatric Cardiac and Transplantation Surgery, New Children\u2019s Hospital, Helsinki University Hospital , 00290 Helsinki,","place":["Finland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Kostolny","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital Cardiothoracic Unit, , London WC1N 3JH,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kalfa","sequence":"additional","affiliation":[{"name":"Section of Congenital and Pediatric Cardiac Surgery, Division of Cardiac, Thoracic, and Vascular Surgery, NY-Presbyterian Morgan Stanley Children\u2019s Hospital, Columbia University Medical Center , New York, NY 10032,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9538-7310","authenticated-orcid":false,"given":"Ren\u00e9","family":"Pr\u00eatre","sequence":"additional","affiliation":[{"name":"Chirurgie Cardiaque P\u00e9diatrique, University Hospital Lausanne , 1011 Lausanne,","place":["Switzerland"]},{"name":"Kinderspital Z\u00fcrich Department of Cardiac Surgery, , 8008 Z\u00fcrich,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Rosser","sequence":"additional","affiliation":[{"name":"Kinderspital Z\u00fcrich Department of Cardiac Surgery, , 8008 Z\u00fcrich,","place":["Switzerland"]},{"name":"Kantonsspital Luzern Department of Cardiac Surgery, , 6004 Luzern,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Tlaskal","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiac Surgery, Kardiocentrum, University Hospital Motol , 150 00 Prague,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Illya","family":"Yemets","sequence":"additional","affiliation":[{"name":"Ukrainian Children\u2019s Cardiac Center Department of Pediatric Cardiac Surgery, , 02000 Kyiv,","place":["Ukraine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander N","family":"Romanyuk","sequence":"additional","affiliation":[{"name":"Ukrainian Children\u2019s Cardiac Center Department of Pediatric Cardiac Surgery, , 02000 Kyiv,","place":["Ukraine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul P","family":"Heinisch","sequence":"additional","affiliation":[{"name":"Division of Congenital Heart Surgery, University Hospital Grosshadern, Ludwig-Maximilians University , 81377 Munich,","place":["Germany"]},{"name":"Department of Congenital and Paediatric Heart Surgery, German Heart Center Munich, School of Medicine, University Hospital of the Technical University Munich , 80636 Munich,","place":["Germany"]},{"name":"Department of Cardiovascular Surgery, Inselspital University Hospital , 3010 Bern,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3024-6514","authenticated-orcid":false,"given":"Alexander","family":"Kadner","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Inselspital University Hospital , 3010 Bern,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"H\u00f6rer","sequence":"additional","affiliation":[{"name":"Division of Congenital Heart Surgery, University Hospital Grosshadern, Ludwig-Maximilians University , 81377 Munich,","place":["Germany"]},{"name":"Department of Congenital and Paediatric Heart Surgery, German Heart Center Munich, School of Medicine, University Hospital of the Technical University Munich , 80636 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