{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T16:43:19Z","timestamp":1790527399831,"version":"4.1.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T00:00:00Z","timestamp":1554681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p\/>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES:<\/jats:title>\n                    <jats:p>This study aims to analyse the impact of a simplified frozen elephant trunk (FET) technique on early outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Between October 2010 and August 2018, 92 consecutive patients (mean age 64.4\u2009\u00b1\u200912.2\u2009years) underwent FET surgery. Underlying pathologies were thoracic aneurysm in 35 patients, acute aortic dissection in 25 patients and chronic dissection in 32 patients. Thirty patients underwent a simplified FET technique with deployment of the stent graft in arch zone 2 with an extra-anatomic bypass to the distal left subclavian artery using the third branch of the Thoraflex\u2122 Hybrid Plexus prosthesis via a supraclavicular access during reperfusion. These patients were compared to 62 patients who received the conventional FET procedure, in which a distal anastomosis is performed in arch zone 3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Circulatory arrest (41.7\u2009\u00b1\u200910.5 vs 76.5\u2009\u00b1\u200933.0\u2009min; P\u2009&lt;\u20090.001) and antegrade cerebral perfusion times (60.9\u2009\u00b1\u200913.5 vs 92.1\u2009\u00b1\u200933.1\u2009min; P\u2009&lt;\u20090.001) were significantly reduced in zone 2 vs zone 3 patients, respectively. The 30-day mortality rate was 3.3% (n\u2009=\u20091) in zone 2 patients vs 17.7% (n\u2009=\u200911) in zone 3 patients (P\u2009=\u20090.75). Stent deployment in zone 2 was associated with significantly reduced rates of postoperative stroke [zone 2: n\u2009=\u20090 (0.0%); zone 3: n\u2009=\u200911 (17.7%), P\u2009=\u20090.046] and recurrent nerve palsy [zone 2: n\u2009=\u20091 (3.3%); zone 3: n\u2009=\u200914 (22.6%), P\u2009=\u20090.020).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Simplifying the FET procedure leads to reduced circulatory arrest and cerebral perfusion times and improves early outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejcts\/ezz082","type":"journal-article","created":{"date-parts":[[2019,2,23]],"date-time":"2019-02-23T15:12:06Z","timestamp":1550934726000},"page":"738-745","source":"Crossref","is-referenced-by-count":42,"title":["Simplified frozen elephant trunk technique for combined open and endovascular treatment of extensive aortic diseases"],"prefix":"10.1093","volume":"56","author":[{"given":"Christian","family":"Detter","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, German Aortic Center Hamburg, University Heart Center Hamburg, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Till Joscha","family":"Demal","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, German Aortic Center Hamburg, University Heart Center Hamburg, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lennart","family":"Bax","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, German Aortic Center Hamburg, University Heart Center Hamburg, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Tsilimparis","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine, German Aortic Center Hamburg, University Heart Center Hamburg, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tilo","family":"K\u00f6lbel","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine, German Aortic Center Hamburg, University Heart Center Hamburg, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yskert","family":"von Kodolitsch","sequence":"additional","affiliation":[{"name":"Department of General and Interventional Cardiology, German Aortic Center Hamburg, University Heart Center Hamburg, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eik","family":"Vettorazzi","sequence":"additional","affiliation":[{"name":"Department of Medical Biometry and Epidemiology, University Hospital Eppendorf, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermann","family":"Reichenspurner","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, German 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