{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:45:28Z","timestamp":1792179928758,"version":"4.4.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p\/><jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>To review the long-term surgical outcomes of ventricular septation for double-inlet left ventricle and reconsider the possibility of ventricular septation as an option of surgical treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Between 1978 and 1994, 22 patients with double-inlet left ventricle underwent ventricular septation. The mean age at operation was 5.3\u2009years (range 0\u201322\u2009years). Follow-up was carried out in 20 of 22 patients (91%) and the mean follow-up period was 14.7\u2009years (range 0\u201339\u2009years).<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Actuarial survival and reoperation-free survival rates at 30\u2009years were 49% and 21%, respectively. To date, 8 patients have been followed up. Among them, atrioventricular valve replacement and permanent pacemaker were required in 4 and 7 patients, respectively. Late cardiac catheter examination at 25.5\u2009years after surgery showed that the median cardiac index was 2.6\u2009l\/min\/m2 (range 2.1\u20133.4\u2009l\/min\/m2), left ventricular end-diastolic pressure was 7\u2009mmHg (range 4\u201311\u2009mmHg), left ventricular ejection fraction was 50% (range 27\u201363%), right ventricular ejection fraction was 53% (range 31\u201366%) and central venous pressure was 6\u2009mmHg (range 4\u201311\u2009mmHg). At the latest follow-up, the New York Heart Association Functional Classification was I for 5 patients, II for 2 patients and III for 1 patient. The median peak oxygen uptake was 52.9% (range 44.1\u201393.5%).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Some patients with double-inlet left ventricle were able to maintain low central venous pressure and a sufficient cardiac index long after ventricular septation. Although the single ventricle strategy remains a first-line treatment, ventricular septation can be a surgical treatment option.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ejcts\/ezz097","type":"journal-article","created":{"date-parts":[[2019,3,5]],"date-time":"2019-03-05T20:36:27Z","timestamp":1551818187000},"page":"898-903","source":"Crossref","is-referenced-by-count":13,"title":["Long-term results of ventricular septation for double-inlet left ventricle\u2020"],"prefix":"10.1093","volume":"56","author":[{"given":"Masatoshi","family":"Shimada","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaya","family":"Hoashi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, 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