{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:47:43Z","timestamp":1760161663414,"version":"3.41.2"},"reference-count":18,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2019,7,14]],"date-time":"2019-07-14T00:00:00Z","timestamp":1563062400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The right ventricular outflow tract reconstruction is a common necessity in congenital cardiac surgery. As homograft availability is limited, alternatives need to be evaluated. The Labcor\u00ae conduit consists of a porcine tricomposite valve assembled inside a bovine pericardium tube. This study presents intermediate-term results for its utilization for right ventricular outflow tract reconstruction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Labcor conduits were implanted in 53 patients (February 2009\u2013July 2016). We analysed perioperative data, freedom from conduit failure and risk factors for conduit dysfunction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The most common diagnosis was Tetralogy of Fallot (n\u2009=\u200920, 37.7%). The median age at surgery was 10.0 [interquartile range (IQR) 4.9\u201314.3] years. Pulmonary artery plasty (n\u2009=\u200937, 69.8%) and augmentation of the right ventricular outflow tract (n\u2009=\u200916, 30.2%) were often part of the procedure. The median conduit size was 21 (range 11\u201325) mm. There was no in-hospital death. The median follow-up after surgery was 4.6 (IQR 3.4\u20135.6) years. Fourteen patients (27.5%) developed conduit failure with stenosis being the main cause. Freedom from conduit failure was 98.0% at 2 and 80.5% at 5 years. The median longevity of the conduit was 7.4\u2009years (95% confidence interval 5.1\u20139.8\u2009years). Younger age and smaller conduit size were related to conduit failure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Utilization of the Labcor conduit revealed acceptable intermediate-term results. The conduit appeared to be functioning sufficiently well within the first 5\u2009years in the majority of patients. The higher rate of failure concerning smaller conduits might be associated with somatic outgrowth; however, conduit degeneration as common and long-term outcome still needs to be evaluated.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezz200","type":"journal-article","created":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T11:08:18Z","timestamp":1560424098000},"source":"Crossref","is-referenced-by-count":4,"title":["Right ventricular outflow tract reconstruction with the Labcor\u00ae stentless valved pulmonary conduit"],"prefix":"10.1093","author":[{"given":"Jill","family":"Jussli-Melchers","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Scheewe","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1575-2865","authenticated-orcid":false,"given":"Jan Hinnerk","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein, Kiel, Germany"},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Hamburg\/Kiel\/L\u00fcbeck, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Grothusen","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Steer","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7406-8006","authenticated-orcid":false,"given":"Inga","family":"Voges","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Logoteta","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"D\u00fctschke","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Medicine, University Hospital Schleswig-Holstein, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Heiner","family":"Kramer","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein, Kiel, Germany"},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Hamburg\/Kiel\/L\u00fcbeck, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Attmann","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,7,13]]},"reference":[{"key":"2019071408555624100_ezz200-B1","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1111\/j.0886-0440.2004.04083.x","article-title":"The Contegra bovine valved jugular vein conduit for pediatric RVOT reconstruction: 4 year experience with 108 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