{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:21:20Z","timestamp":1790083280245,"version":"4.0.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T00:00:00Z","timestamp":1563494400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Tricuspid regurgitation (TR) is common in patients receiving a left ventricular assist device (LVAD). Controversy exists as to whether concomitant tricuspid valve surgery (TVS) is beneficial in currently treated patients. Therefore, our goal was to investigate the effect of TVS concomitant with a LVAD implant.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>The European Registry for Patients with Mechanical Circulatory Support was used to identify adult patients. Matched patients with and without concomitant TVS were compared using a propensity score matching strategy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>In total, 3323 patients underwent LVAD implantation of which 299 (9%) had TVS. After matching, 258 patients without TVS were matched to 258 patients with TVS. In the matched population, hospital deaths, days on inotropic support, temporary right ventricular assist device implants and hospital stay were comparable, whereas stay in the intensive care unit was higher in the TVS cohort (11 vs 15\u2009days; P\u2009=\u20090.026). Late deaths (P\u2009=\u20090.17), cumulative incidence of unexpected hospital readmission (P\u2009=\u20090.15) and right heart failure (P\u2009=\u20090.55) were comparable between patients with and without concomitant TVS. In the matched population, probability of moderate-to-severe TR immediately after surgery was lower in patients with concomitant TVS compared to patients without TVS (33% vs 70%; P\u2009=\u20090.001). Nevertheless, the probability of moderate-to-severe TR decreased more quickly in patients without TVS (P\u2009=\u20090.030), resulting in comparable probabilities of moderate-to-severe TR within 1.5\u2009years of follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>In matched patients, TVS concomitant with LVAD implant does not seem to be associated with better clinical outcomes. Concomitant TVS reduced TR significantly early after LVAD implant; however, differences in probability of TR disappeared during the follow-up period.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezz208","type":"journal-article","created":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T15:09:09Z","timestamp":1562684949000},"page":"1081-1089","source":"Crossref","is-referenced-by-count":41,"title":["Outcomes after tricuspid valve surgery concomitant with left ventricular assist device implantation in the EUROMACS registry: a propensity score matched analysis"],"prefix":"10.1093","volume":"56","author":[{"given":"Kevin M","family":"Veen","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kadir","family":"Caliskan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Erasmus MC, Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theo M M H","family":"de By","sequence":"additional","affiliation":[{"name":"EUROMACS Registry, EACTS, Windsor, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mostafa M","family":"Mokhles","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0758-3539","authenticated-orcid":false,"given":"Osama I","family":"Soliman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Erasmus MC, Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Mohacsi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Schoenrath","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Berlin, Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Gummert","sequence":"additional","affiliation":[{"name":"Department for Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre NRW, Ruhr-University Bochum, Bad Oeynhausen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lech","family":"Paluszkiewicz","sequence":"additional","affiliation":[{"name":"Department for Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre NRW, Ruhr-University Bochum, Bad Oeynhausen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Netuka","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic"},{"name":"Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3689-0477","authenticated-orcid":false,"given":"Antonio","family":"Loforte","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit, Policlinico di S. Orsola, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuriy","family":"Pya","sequence":"additional","affiliation":[{"name":"National Research Cardiac Surgery Center, Astana, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9809-5623","authenticated-orcid":false,"given":"Johanna J M","family":"Takkenberg","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad J J C","family":"Bogers","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,7,18]]},"reference":[{"key":"2019111904002710000_ezz208-B1","doi-asserted-by":"crossref","first-page":"518.","DOI":"10.1016\/j.jchf.2017.02.016","article-title":"Risk assessment and comparative effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients: the ROADMAP study 2-year results","volume":"5","author":"Starling","year":"2017","journal-title":"JACC Heart Fail"},{"key":"2019111904002710000_ezz208-B2","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1056\/NEJMoa012175","article-title":"Long-term use of a left ventricular assist device for end-stage heart failure","volume":"345","author":"Rose","year":"2001","journal-title":"N Engl J Med"},{"key":"2019111904002710000_ezz208-B3","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1016\/j.athoracsur.2011.01.053","article-title":"Impact of tricuspid valve regurgitation in patients treated with implantable left ventricular assist devices","volume":"91","author":"Piacentino","year":"2011","journal-title":"Ann Thorac Surg"},{"key":"2019111904002710000_ezz208-B4","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.healun.2012.09.013","article-title":"The 2013 International Society for Heart and Lung Transplantation guidelines for mechanical circulatory support: executive summary","volume":"32","author":"Feldman","year":"2013","journal-title":"J Heart Lung Transplant"},{"key":"2019111904002710000_ezz208-B5","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1093\/ejcts\/ezy150","article-title":"Left ventricular assist device implantation with and without concomitant tricuspid valve surgery: a systematic review and meta-analysis","volume":"54","author":"Veen","year":"2018","journal-title":"Eur J Cardiothorac Surg"},{"key":"2019111904002710000_ezz208-B6","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1093\/ejcts\/ezv096","article-title":"The European Registry for Patients with Mechanical Circulatory Support (EUROMACS): first annual report","volume":"47","author":"de By","year":"2015","journal-title":"Eur J Cardiothorac Surg"},{"key":"2019111904002710000_ezz208-B7","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.jamcollsurg.2008.11.016","article-title":"INTERMACS: interval analysis of registry data","volume":"208","author":"Holman","year":"2009","journal-title":"J Am Coll Surg"},{"key":"2019111904002710000_ezz208-B8","first-page":"67","article-title":"mice: multivariate imputation by chained equations in R","volume":"45","author":"van Buuren","year":"2011","journal-title":"J Stat Softw"},{"key":"2019111904002710000_ezz208-B9","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1002\/9780470316696","volume-title":"Multiple Imputation for Nonresponse in Surveys","author":"Rubin","year":"1987"},{"key":"2019111904002710000_ezz208-B10","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2147\/POR.S122563","article-title":"An evaluation of exact matching and propensity score methods as applied in a comparative effectiveness study of inhaled corticosteroids in asthma","volume":"8","author":"Burden","year":"2017","journal-title":"Pragmat Obs Res"},{"key":"2019111904002710000_ezz208-B11","first-page":"267","author":"Tibshirani","year":"1996"},{"key":"2019111904002710000_ezz208-B12","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.athoracsur.2007.12.012","article-title":"Measuring follow-up completeness","volume":"85","author":"Wu","year":"2008","journal-title":"Ann Thorac Surg"},{"key":"2019111904002710000_ezz208-B13","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.healun.2014.01.861","article-title":"Concomitant tricuspid valve surgery during implantation of continuous-flow left ventricular assist devices: a Society of Thoracic Surgeons database analysis","volume":"33","author":"Robertson","year":"2014","journal-title":"J Heart Lung Transplant"},{"key":"2019111904002710000_ezz208-B14","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1016\/j.athoracsur.2016.03.040","article-title":"Limited utility of tricuspid valve repair at the time of left ventricular assist device implantation","volume":"101","author":"Song","year":"2016","journal-title":"Ann Thorac Surg"},{"key":"2019111904002710000_ezz208-B15","doi-asserted-by":"crossref","first-page":"e008813","DOI":"10.1161\/JAHA.118.008813","article-title":"Prevalence, predictors, and prognostic value of residual tricuspid regurgitation in patients with left ventricular assist device","volume":"7","author":"Nakanishi","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"2019111904002710000_ezz208-B16","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.healun.2010.01.011","article-title":"Clinical management of continuous-flow left ventricular assist devices in advanced heart failure","volume":"29(Suppl 4)","author":"Slaughter","year":"2010","journal-title":"J Heart Lung Transplant"},{"key":"2019111904002710000_ezz208-B17","first-page":"II309","article-title":"Influence of left ventricular assist on valvular regurgitation","volume":"88","author":"Holman","year":"1993","journal-title":"Circulation"},{"key":"2019111904002710000_ezz208-B18","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1161\/CIRCULATIONAHA.108.842773","article-title":"The tricuspid valve: current perspective and evolving management of tricuspid regurgitation","volume":"119","author":"Rogers","year":"2009","journal-title":"Circulation"},{"key":"2019111904002710000_ezz208-B19","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.jtcvs.2010.08.010","article-title":"Acute impact of left ventricular unloading by left ventricular assist device on the right ventricle geometry and function: effect of nitric oxide inhalation","volume":"141","author":"Kukucka","year":"2011","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2019111904002710000_ezz208-B20","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.healun.2012.12.018","article-title":"Impact of continuous-flow left ventricular assist device support on right ventricular function","volume":"32","author":"Morgan","year":"2013","journal-title":"J Heart Lung Transplant"},{"key":"2019111904002710000_ezz208-B21","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1016\/j.jacc.2017.02.055","article-title":"Tricuspid valve dysfunction following pacemaker or cardioverter-defibrillator implantation","volume":"69","author":"Chang","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2019111904002710000_ezz208-B22","doi-asserted-by":"crossref","first-page":"2902","DOI":"10.1253\/circj.CJ-11-0718","article-title":"Progression of isolated tricuspid regurgitation late after left-sided valve surgery. Clinical features and mechanisms","volume":"75","author":"Izumi","year":"2011","journal-title":"Circ J"},{"key":"2019111904002710000_ezz208-B23","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1136\/hrt.2008.152793","article-title":"Factors associated with development of late significant tricuspid regurgitation after successful left-sided valve surgery","volume":"95","author":"Song","year":"2009","journal-title":"Heart"},{"key":"2019111904002710000_ezz208-B24","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/ejcts\/ezx320","article-title":"The European Registry for Patients with Mechanical Circulatory Support (EUROMACS) of the European Association for Cardio-Thoracic Surgery (EACTS): second report","volume":"53","author":"de By","year":"2017","journal-title":"Eur J Cardiothorac Surg"},{"key":"2019111904002710000_ezz208-B25","first-page":"634","article-title":". Tricuspid regurgitation diagnosis and treatment","volume":"38","author":"Arsalan","year":"2017","journal-title":"Eur Heart J"}],"container-title":["European Journal of Cardio-Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ejcts\/article-pdf\/56\/6\/1081\/30960964\/ezz208.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ejcts\/article-pdf\/56\/6\/1081\/30960964\/ezz208.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T04:01:10Z","timestamp":1574136070000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejcts\/article\/56\/6\/1081\/5535675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,18]]},"references-count":25,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,7,18]]},"published-print":{"date-parts":[[2019,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ejcts\/ezz208","relation":{},"ISSN":["1010-7940","1873-734X"],"issn-type":[{"value":"1010-7940","type":"print"},{"value":"1873-734X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,12]]},"published":{"date-parts":[[2019,7,18]]}}}