{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T08:51:03Z","timestamp":1793436663153,"version":"4.5.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T00:00:00Z","timestamp":1579737600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Some studies have suggested that root remodelling is unsuitable as valve-sparing aortic root replacement in children because of the increased risk of valve failure. This study reviewed our experience with root remodelling in children.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>All patients who underwent root remodelling at the age of \u226418\u2009years between 1999 and 2016 were evaluated. In 2004, cusp effective height was measured intraoperatively and prolapse was corrected with central plication on the cusp. Suture annuloplasty was introduced after 2009 for annular dilatation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>There were 17 consecutive patients. The median age at operation was 14 (2.8\u201318) years. Aortic valve morphology was tricuspid in 10 patients, bicuspid in 5 patients, unicuspid in 1 patient and a pulmonary autograft in 1 patient. Marfan syndrome, Loeys-Dietz syndrome and other connective tissue diseases were present in 11, 1 and 2 patients, respectively. Five patients had more than moderate aortic regurgitation. The median graft size used for root remodelling was 24 (18\u201326) mm. Cusp repair and annuloplasty were performed in 15 and 14 patients, respectively. The mean follow-up time was 6.5\u2009\u00b1\u20094.3\u2009years. One patient with preoperatively severely depressed ventricular function died in the hospital from persistent heart failure. One patient (operated on before 2004) required aortic valve reoperation due to cusp prolapse. One patient with a unicuspid valve had developed moderate aortic regurgitation, and the other 14 patients had mild or less regurgitation. The median diameter of the sinus of Valsalva at the last follow-up was 36 (30\u201343) mm, Z-score of 1.5 (\u22123.5 to 3.9).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Root remodelling can be performed in children with favourable results by appropriate cusp repair and annuloplasty.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejcts\/ezz380","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T20:08:54Z","timestamp":1579118934000},"page":"1091-1097","source":"Crossref","is-referenced-by-count":8,"title":["Reexamining remodelling in children"],"prefix":"10.1093","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9415-5788","authenticated-orcid":false,"given":"Shunsuke","family":"Matsushima","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"He\u00df","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Renata","family":"L\u00e4mmerzahl","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irem","family":"Karliova","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Giebels","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg, 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