{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T01:30:16Z","timestamp":1789695016650,"version":"4.0.1"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","award":["32473B_162608"],"award-info":[{"award-number":["32473B_162608"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Swiss Academy of Medical Sciences and G. & J. 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Psychopathologic findings, commonly used for PP diagnosis in clinical practice, are rarely evaluated in AVP-D patients, and no comparative data between the two conditions currently exist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Data from two studies involving 82 participants [39 AVP-D, 28 PP, and 15 healthy controls (HC)].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Psychological evaluations were conducted using standardized questionnaires measuring anxiety [State-Trait Anxiety Inventory (STAI)], alexithymia [Toronto Alexithymia Scale (TAS-20)], depressive symptoms (Beck's Depression Inventory-II (BDI-II), and overall mental health [Short Form-36 Health Survey (SF-36)]. Higher STAI, TAS-20, and BDI-II scores suggest elevated anxiety, alexithymia, and depression, while higher SF-36 scores signify better overall mental health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared to HC, patients with AVP-D and PP showed higher levels of anxiety (HC 28 points [24\u201331] vs AVP-D 36 points [31\u201345]; vs PP 38 points [33\u201346], P &amp;lt; .01), alexithymia (HC 30 points [29\u201337] vs AVP-D 43 points [35\u201354]; vs PP 46 points [37\u201355], P &amp;lt; .01), and depression (HC 1 point [0\u20132] vs AVP-D 7 points [4\u201314]; vs PP 7 points [3\u201313], P &amp;lt; .01). Levels of anxiety, alexithymia, and depression showed no difference between both patient groups (P = .58, P = .90, P = .50, respectively). Compared to HC, patients with AVP-D and PP reported similarly reduced self-reported overall mental health scores (HC 84 [68\u201388] vs AVP-D 60 [52\u201380], P = .05; vs PP 60 [47\u201374], P &amp;lt; .01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study reveals heightened anxiety, alexithymia, depression, and diminished overall mental health in patients with AVP-D and PP. The results emphasize the need for careful interpretation of psychopathological characteristics to differentiate between AVP-D and PP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejendo\/lvae040","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T08:23:51Z","timestamp":1711700631000},"page":"354-362","source":"Crossref","is-referenced-by-count":13,"title":["Psychopathological characteristics in patients with arginine vasopressin deficiency (central diabetes insipidus) and primary polydipsia compared to healthy controls"],"prefix":"10.1093","volume":"190","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5442-7304","authenticated-orcid":false,"given":"Cihan","family":"Atila","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel , 4031 Basel , Switzerland"},{"name":"Department of Clinical Research, University of Basel , 4031 Basel , 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