{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T03:26:49Z","timestamp":1793849209999,"version":"4.6.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000871","name":"Mayo Clinic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012264","name":"NIH","doi-asserted-by":"publisher","award":["K23HL164901"],"award-info":[{"award-number":["K23HL164901"]}],"id":[{"id":"10.13039\/501100012264","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012264","name":"NIH","doi-asserted-by":"publisher","award":["R01 HL128526"],"award-info":[{"award-number":["R01 HL128526"]}],"id":[{"id":"10.13039\/501100012264","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012264","name":"NIH","doi-asserted-by":"publisher","award":["R01 HL162828"],"award-info":[{"award-number":["R01 HL162828"]}],"id":[{"id":"10.13039\/501100012264","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012264","name":"NIH","doi-asserted-by":"publisher","award":["U01 HL160226"],"award-info":[{"award-number":["U01 HL160226"]}],"id":[{"id":"10.13039\/501100012264","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIH\/NHLBI","award":["W81XWH2210245"],"award-info":[{"award-number":["W81XWH2210245"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,15]]},"DOI":"10.1093\/ejhf\/xuag069","type":"journal-article","created":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T12:43:45Z","timestamp":1772714625000},"page":"487-489","source":"Crossref","is-referenced-by-count":2,"title":["Very high-dose loop diuretics for worsening heart failure\u2014a randomized pilot trial"],"prefix":"10.1093","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1116-8541","authenticated-orcid":false,"given":"Yogesh N V","family":"Reddy","sequence":"first","affiliation":[{"name":"The Department of Cardiovascular Medicine, Mayo Clinic , Rochester, 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary-Tiffany","family":"Oduah","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Medicine, Mayo Clinic , Rochester, 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadi","family":"Adel","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Medicine, Mayo Clinic , Rochester, 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R","family":"Miranda","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Medicine, Mayo Clinic , Rochester, 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Greenlund","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Medicine, Mayo Clinic , Rochester, 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent R","family":"Bailey","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Medicine, Mayo Clinic , Rochester, 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Testani","sequence":"additional","affiliation":[{"name":"The Department of Internal Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine , New Haven, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4045-4341","authenticated-orcid":false,"given":"Virend K","family":"Somers","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Medicine, Mayo Clinic , Rochester, 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry A","family":"Borlaug","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Medicine, Mayo Clinic , Rochester, 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveen L","family":"Pereira","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Medicine, Mayo Clinic , Rochester, 200 First Street SW, Rochester, MN 55905 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"2026091504182263400_xuag069-B1","doi-asserted-by":"publisher","first-page":"2471","DOI":"10.1016\/j.jacc.2025.08.051","article-title":"Effect of vericiguat on total heart failure events in compensated outpatients with HFrEF: insights from VICTOR","volume":"86","author":"Zannad","year":"2025","journal-title":"J Am Coll Cardiol"},{"key":"2026091504182263400_xuag069-B2","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1056\/NEJMoa1005419","article-title":"Diuretic strategies in patients with acute decompensated heart failure","volume":"364","author":"Felker","year":"2011","journal-title":"N Engl J Med"},{"key":"2026091504182263400_xuag069-B3","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.1016\/j.jchf.2024.04.002","article-title":"Contemporary decongestion strategies in patients hospitalized for heart failure: a national community-based cohort study","volume":"12","author":"Zheng","year":"2024","journal-title":"JACC Heart Fail"},{"key":"2026091504182263400_xuag069-B4","doi-asserted-by":"publisher","first-page":"1964","DOI":"10.1056\/NEJMra1703100","article-title":"Diuretic treatment in heart failure","volume":"377","author":"Ellison","year":"2017","journal-title":"N Engl J Med"},{"key":"2026091504182263400_xuag069-B5","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1161\/01.CIR.74.6.1303","article-title":"Maintenance of cardiac output with normal filling pressures in patients with dilated heart failure","volume":"74","author":"Stevenson","year":"1986","journal-title":"Circulation"}],"container-title":["European Journal of Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurjhf\/advance-article-pdf\/doi\/10.1093\/ejhf\/xuag069\/67281668\/xuag069.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/28\/3\/487\/67281668\/xuag069.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/28\/3\/487\/67281668\/xuag069.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T08:23:17Z","timestamp":1789460597000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjhf\/article\/28\/3\/487\/8512398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,3,9]]},"published-print":{"date-parts":[[2026,9,15]]}},"URL":"https:\/\/doi.org\/10.1093\/ejhf\/xuag069","relation":{},"ISSN":["1388-9842","1879-0844"],"issn-type":[{"value":"1388-9842","type":"print"},{"value":"1879-0844","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,3]]},"published":{"date-parts":[[2026,3]]}}}