{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T15:03:28Z","timestamp":1789571008464,"version":"build-2803163510"},"reference-count":5,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1093\/ejhf\/xuag198","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T12:21:46Z","timestamp":1781612506000},"source":"Crossref","is-referenced-by-count":0,"title":["Interpreting fragility indices in finerenone trials: complementary insights into statistical stability"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4559-1292","authenticated-orcid":false,"given":"Marco","family":"Zuin","sequence":"first","affiliation":[{"name":"Department of Translational Medicine, University of Ferrara , Ferrara ,","place":["Italy"]},{"name":"Division of Cardiology, South Padova General Hospitals , Monselice, Padua ,","place":["Italy"]},{"name":"Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padova , Padua ,","place":["Italy"]},{"name":"PhD Program in Translation Specialistic Medicine \u2018G.B. Morgagni\u2019, Curriculum Cardiovascular Sciences, University of Padua , Padua ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1722-2983","authenticated-orcid":false,"given":"Gregory","family":"Piazza","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School , 75 Francis St, Boston, MA 02115 ,","place":["USA"]},{"name":"Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School , Boston, MA 02115 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"2026091610163291400_xuag198-B1","doi-asserted-by":"publisher","DOI":"10.1093\/ejhf\/xuag150","article-title":"Fragility analysis of cardiovascular outcomes with finerenone in patients with type 2 diabetes Mellitus and chronic kidney disease","author":"Zuin","year":"5, 2026","journal-title":"Eur J Heart Fail"},{"key":"2026091610163291400_xuag198-B2","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1016\/j.jclinepi.2013.10.019","article-title":"The statistical significance of randomized controlled trial results is frequently fragile: a case for a fragility Index","volume":"67","author":"Walsh","year":"2014","journal-title":"J Clin Epidemiol"},{"key":"2026091610163291400_xuag198-B3","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1093\/eurheartj\/ehab777","article-title":"Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis","volume":"43","author":"Agarwal","year":"2022","journal-title":"Eur Heart J"},{"key":"2026091610163291400_xuag198-B4","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1007\/s11606-021-06999-9","article-title":"The fragility Index for assessing the robustness of the statistically significant results of experimental clinical studies","volume":"37","author":"Ho","year":"2022","journal-title":"J Gen Intern Med"},{"key":"2026091610163291400_xuag198-B5","doi-asserted-by":"publisher","first-page":"2252","DOI":"10.1056\/NEJMoa2110956","article-title":"Cardiovascular events with finerenone in kidney disease and type 2 diabetes","volume":"385","author":"Pitt","year":"2021","journal-title":"N Engl J Med"}],"container-title":["European Journal of Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurjhf\/advance-article-pdf\/doi\/10.1093\/ejhf\/xuag198\/71123191\/xuag198.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/advance-article-pdf\/doi\/10.1093\/ejhf\/xuag198\/71123191\/xuag198.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T14:16:36Z","timestamp":1789568196000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjhf\/advance-article\/doi\/10.1093\/ejhf\/xuag198\/8802126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,16]]},"references-count":5,"URL":"https:\/\/doi.org\/10.1093\/ejhf\/xuag198","relation":{},"ISSN":["1388-9842","1879-0844"],"issn-type":[{"value":"1388-9842","type":"print"},{"value":"1879-0844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,16]]},"article-number":"xuag198"}}