{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:18:37Z","timestamp":1787008717848,"version":"build-2736575974"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T00:00:00Z","timestamp":1631836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,24]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study was to evaluate intraoral scanning (IOS) in infants, neonates, and small children with craniofacial anomalies for its feasibility, scanning duration, and success rate. Impression taking in vulnerable patients can be potentially life-threatening, with the risk of airway obstruction and aspiration of impression material. The advantage of increasingly digitalized dentistry is demonstrated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>IOS was captured with the Trios 3\u00ae (3Shape, Copenhagen, Denmark) intraoral scanner. The underlying disorders were divided into cleft lip and palate (CLP), Trisomy 21 (T21), Robin Sequence (RS), Treacher Collins syndrome (TC), and isolated mandibular retrognathia (MR). Scan data were analysed by scanning duration, number of images, possible correlations of these factors with the different craniofacial disorders, patient age, and relationship between first and subsequent scans. Clinical experiences with the repeated digital impressions are described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patient data of 141 scans in 83 patients were analysed within an 11-month period. Patients had a median age of 137 days. Median scanning duration was 138 seconds, resulting in a median of 352 images. There was a statistically significant difference in scanning duration (P = 0.001) between infants and neonates. IOS took longest in patients with CLP (537 seconds) and shortest in T21 patients (21 seconds), although there was no statistically significant difference between aetiologies. There was no statistically significant difference between first and subsequent scans in scanning duration. In four cases the IOS had to be repeated, and one patient ultimately required conventional impression taking (all CLP patients; success rate 94%). No severe adverse events occurred.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>IOS is a fast, safe, and feasible procedure for neonates, small children, and infants with craniofacial malformations. One special challenge for both technician and user was identified in patients with CLP, though implementing this new approach of digital impression taking was otherwise found to be highly successful in everyday clinical routine.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ejo\/cjab068","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T07:35:50Z","timestamp":1631086550000},"page":"279-286","source":"Crossref","is-referenced-by-count":45,"title":["Intraoral scanning of neonates and infants with craniofacial disorders: feasibility, scanning duration, and clinical experience"],"prefix":"10.1093","volume":"44","author":[{"given":"Christina","family":"Weise","sequence":"first","affiliation":[{"name":"Department of Orthodontics, University Hospital Tuebingen, Germany"},{"name":"Center for Cleft Palate and Craniofacial Malformations, University Hospital Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Frank","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, University Hospital Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia","family":"Wiechers","sequence":"additional","affiliation":[{"name":"Center for Cleft Palate and Craniofacial Malformations, University Hospital Tuebingen, Germany"},{"name":"Department of Neonatology, University Hospital Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8443-740X","authenticated-orcid":false,"given":"Hannes","family":"Weise","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, University Hospital Tuebingen, Germany"},{"name":"Center for Cleft Palate and Craniofacial Malformations, University Hospital Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siegmar","family":"Reinert","sequence":"additional","affiliation":[{"name":"Center for Cleft Palate and Craniofacial Malformations, University Hospital Tuebingen, Germany"},{"name":"Department of Oral and Maxillofacial Surgery, University Hospital Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Koos","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, University Hospital Tuebingen, Germany"},{"name":"Center for Cleft Palate and Craniofacial Malformations, University Hospital Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1645-929X","authenticated-orcid":false,"given":"Alexander B","family":"Xepapadeas","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, University Hospital Tuebingen, Germany"},{"name":"Center for Cleft Palate and Craniofacial Malformations, University Hospital Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,9,17]]},"reference":[{"key":"2022052408564489400_CIT0001","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1053\/j.sodo.2004.05.007","article-title":"Digital models: an introduction","volume":"10","author":"Matthew","year":"2004","journal-title":"Seminars in Orthodontics"},{"key":"2022052408564489400_CIT0002","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1179\/1465312512Z.00000000023","article-title":"Digital versus plaster study models: how accurate and reproducible are they?","volume":"39","author":"Abizadeh","year":"2012","journal-title":"Journal of Orthodontics"},{"key":"2022052408564489400_CIT0003","first-page":"337","article-title":"Intraoral digital scanners","volume":"48","author":"Kravitz","year":"2014","journal-title":"Journal of Clinical Orthodontics"},{"key":"2022052408564489400_CIT0004","first-page":"9","article-title":"In-vitro evaluation of the accuracy of conventional and digital methods of obtaining full-arch dental impressions","volume":"46","author":"Ender","year":"2015","journal-title":"Quintessence International (Berlin, Germany: 1985)"},{"key":"2022052408564489400_CIT0005","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.prosdent.2015.09.011","article-title":"In vivo precision of conventional and digital methods of obtaining complete-arch dental impressions","volume":"115","author":"Ender","year":"2016","journal-title":"The Journal of Prosthetic Dentistry"},{"key":"2022052408564489400_CIT0006","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0022-3913(13)60028-1","article-title":"Accuracy of complete-arch dental impressions: a new method of measuring trueness and precision","volume":"102","author":"Ender","year":"2013","journal-title":"The Journal of Prothetic Dentistry"},{"key":"2022052408564489400_CIT0007","doi-asserted-by":"crossref","first-page":"914","DOI":"10.14219\/jada.archive.2013.0209","article-title":"Assessing the feasibility and accuracy of digitizing edentulous jaws","volume":"144","author":"Patzelt","year":"2013","journal-title":"Journal of the American Dental Association (1939)"},{"key":"2022052408564489400_CIT0008","doi-asserted-by":"crossref","first-page":"542","DOI":"10.14219\/jada.2014.23","article-title":"The time efficiency of intraoral scanners","volume":"145","author":"Patzelt","year":"2014","journal-title":"Journal of the American Dental Association (1939)"},{"key":"2022052408564489400_CIT0009","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1007\/s00784-015-1626-x","article-title":"A new method for the evaluation of the accuracy of full-arch digital impressions in vitro","volume":"20","author":"G\u00fcth","year":"2016","journal-title":"Clinical Oral Investigations"},{"key":"2022052408564489400_CIT0010","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1007\/s00784-016-1902-4","article-title":"Accuracy of five intraoral scanners compared to indirect digitalization","volume":"21","author":"G\u00fcth","year":"2017","journal-title":"Clinical Oral Investigations"},{"key":"2022052408564489400_CIT0011","first-page":"41","article-title":"Accuracy and efficiency of full-arch digitalization and 3D printing: a comparison between desktop model scanners, an intraoral scanner, a CBCT model scan, and stereolithographic 3D printing","volume":"48","author":"Wesemann","year":"2017","journal-title":"Quintessence International (Berlin, Germany: 1985)"},{"key":"2022052408564489400_CIT0012","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.2319\/031510-150.1","article-title":"Dimensional change over time of extended-storage alginate impression materials","volume":"80","author":"Walker","year":"2010","journal-title":"The Angle Orthodontist"},{"key":"2022052408564489400_CIT0013","doi-asserted-by":"crossref","first-page":"761","DOI":"10.14219\/jada.archive.2008.0258","article-title":"Will digital impressions eliminate the current problems with conventional impressions?","volume":"139","author":"Christensen","year":"2008","journal-title":"Journal of the American Dental Association (1939)"},{"key":"2022052408564489400_CIT0014","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.14219\/jada.archive.2009.0054","article-title":"Impressions are changing: deciding on conventional, digital or digital plus in-office milling","volume":"140","author":"Christensen","year":"2009","journal-title":"Journal of the American Dental Association (1939)"},{"key":"2022052408564489400_CIT0015","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1007\/s00784-013-1132-y","article-title":"Accuracy of full-arch scans using intraoral scanners","volume":"18","author":"Patzelt","year":"2014","journal-title":"Clinical Oral Investigations"},{"key":"2022052408564489400_CIT0016","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1472-6831-14-10","article-title":"Comparison of digital and conventional impression techniques: evaluation of patients\u2019 perception, treatment comfort, effectiveness and clinical outcomes","volume":"14","author":"Yuzbasioglu","year":"2014","journal-title":"BMC Oral Health"},{"key":"2022052408564489400_CIT0017","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1111\/j.1754-4505.1988.tb00741.x","article-title":"An impression procedure for the neonatal patient with a cleft palate","volume":"8","author":"Lipp","year":"1988","journal-title":"Special Care in Dentistry"},{"key":"2022052408564489400_CIT0018","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1179\/bjo.22.4.299","article-title":"A report on the hazards encountered when taking neonatal cleft palate impressions (1983\u20131992)","volume":"22","author":"Chate","year":"1995","journal-title":"British Journal of Orthodontics"},{"key":"2022052408564489400_CIT0019","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1597\/15-036","article-title":"Intraoral 3D scanning or dental impression for the assessment of dental arch relationships in cleft care: which is superior?","volume":"53","author":"Chalmers","year":"2016","journal-title":"The Cleft Palate-Craniofacial Journal"},{"key":"2022052408564489400_CIT0020","doi-asserted-by":"crossref","first-page":"998","DOI":"10.12968\/denu.2017.44.10.998","article-title":"What\u2019s left in the cleft? A rare complication following displacement of dental impression material into a palatal cleft","volume":"44","author":"Datta","year":"2017","journal-title":"Dental Update"},{"key":"2022052408564489400_CIT0021","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1186\/s12903-020-01159-7","article-title":"Technical note on introducing a digital workflow for newborns with craniofacial anomalies based on intraoral scans\u2014part II: 3D printed T\u00fcbingen palatal plate prototype for newborns with Robin sequence","volume":"20","author":"Xepapadeas","year":"2020","journal-title":"BMC Oral Health"},{"key":"2022052408564489400_CIT0022","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12903-020-1001-4","article-title":"Technical note on introducing a digital workflow for newborns with craniofacial anomalies based on intraoral scans\u2014part I: 3D printed and milled palatal stimulation plate for trisomy 21","volume":"20","author":"Xepapadeas","year":"2020","journal-title":"BMC Oral Health"},{"key":"2022052408564489400_CIT0023","first-page":"1242","article-title":"Digitaler Workflow zur Herstellung der Gaumenabdeckplatte","volume":"45","author":"Xepapadeas","year":"2019","journal-title":"Quintessenz Zahntechnik"},{"key":"2022052408564489400_CIT0024","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1177\/1055665619835082","article-title":"Intraoral digital impression technique for a neonate with bilateral cleft lip and palate","volume":"56","author":"Patel","year":"2019","journal-title":"The Cleft Palate-Craniofacial Journal"},{"key":"2022052408564489400_CIT0025","first-page":"251","article-title":"Fully digital workflow for presurgical orthodontic plate in cleft lip and palate patients","volume":"21","author":"Krey","year":"2018","journal-title":"International Journal of Computerized Dentistry"},{"key":"2022052408564489400_CIT0026","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1097\/SCS.0000000000006258","article-title":"Full digital workflow of nasoalveolar molding treatment in infants with cleft lip and palate","volume":"31","author":"Gong","year":"2020","journal-title":"The Journal of Craniofacial Surgery"},{"key":"2022052408564489400_CIT0027","doi-asserted-by":"crossref","DOI":"10.3390\/ma14154103","article-title":"Accuracy evaluation of additively and subtractively fabricated palatal plate orthodontic appliances for newborns and infants\u2014an in vitro study","volume":"14","author":"Aretxabaleta","year":"2021","journal-title":"Materials"},{"key":"2022052408564489400_CIT0028","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1016\/j.jcms.2019.08.002","article-title":"The T\u00fcbingen palatal plate approach to Robin sequence: summary of current evidence","volume":"47","author":"Poets","year":"2019","journal-title":"Journal of Cranio-Maxillo-Facial Surgery"},{"key":"2022052408564489400_CIT0029","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/BF03040408","article-title":"Die T\u00fcbinger Gaumenplatte\u2014Ein innovatives Therapiekonzept bei Pierre-Robin-Sequenz","volume":"115","author":"von Bodman","year":"2003","journal-title":"Wiener Klinische Wochenschrift"},{"key":"2022052408564489400_CIT0030","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/jopr.12218","article-title":"Intraoral digital impression technique: a review","volume":"24","author":"Ting-Shu","year":"2015","journal-title":"Journal of Prosthodontics"},{"key":"2022052408564489400_CIT0031","first-page":"392","article-title":"A stepwise guide for easy, rapid and accurate oral impression taking for newborn cleft lip\/palate infants","volume":"8","author":"Abdel-Rahman","year":"2012","journal-title":"Journal of American Science"},{"key":"2022052408564489400_CIT0032","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0889-5406(86)90028-4","article-title":"Cleft lip and palate: the orthodontist\u2019s youngest patient","volume":"90","author":"Jacobson","year":"1986","journal-title":"American Journal of Orthodontics and Dentofacial Orthopedics"},{"key":"2022052408564489400_CIT0033","first-page":"247","article-title":"Early maxillary orthopedics for the newborn cleft lip and palate patient","volume":"54","author":"Jacobson","year":"1984","journal-title":"The Angle Orthodontist"},{"key":"2022052408564489400_CIT0034","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1186\/s12903-020-01278-1","article-title":"Learning curve of digital intraoral scanning\u2014an in vivo study","volume":"20","author":"R\u00f3th","year":"2020","journal-title":"BMC Oral Health"},{"key":"2022052408564489400_CIT0035","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1177\/1055665619889807","article-title":"OrthoAligner \u201cNAM\u201d: a case series of presurgical infant orthopedics (PSIO) using clear aligners","volume":"57","author":"Batra","year":"2020","journal-title":"The Cleft Palate-Craniofacial Journal"},{"key":"2022052408564489400_CIT0036","doi-asserted-by":"crossref","first-page":"e0158800","DOI":"10.1371\/journal.pone.0158800","article-title":"Accuracy of intraoral digital impressions for whole upper jaws, including full dentitions and palatal soft tissues","volume":"11","author":"Gan","year":"2016","journal-title":"PLoS One"},{"key":"2022052408564489400_CIT0037","doi-asserted-by":"crossref","first-page":"377","DOI":"10.11607\/ijp.5741","article-title":"Using intraoral scanning to capture complete denture impressions, tooth positions, and centric relation records","volume":"31","author":"Goodacre","year":"2018","journal-title":"International Journal of Prosthodontics"},{"key":"2022052408564489400_CIT0038","doi-asserted-by":"crossref","first-page":"76","DOI":"10.4103\/0972-4052.55248","article-title":"Caring for cleft lip and palate infants: impression procedures and appliances in use","volume":"9","author":"Sabarinath","year":"2009","journal-title":"The Journal of Indian Prosthodontic Society"},{"key":"2022052408564489400_CIT0039","volume-title":"Bluestone and Stool\u2019s: Pediatric Otolaryngology (2-Volume Set)","author":"Bluestone","year":"1983"},{"key":"2022052408564489400_CIT0040","first-page":"754","volume-title":"Contemporary Orthodontics","author":"Proffit","year":"2013","edition":"5"},{"key":"2022052408564489400_CIT0041","first-page":"129","article-title":"[Accuracy of three intraoral scans for primary impressions of edentulous jaws]","volume":"52","author":"Cao","year":"2020","journal-title":"Beijing da xue xue bao. Yi xue ban"},{"key":"2022052408564489400_CIT0042","first-page":"1","article-title":"Digital intraoral scanners and alginate impressions in reproducing full dental arches: a comparative 3D assessment","volume":"10","author":"Lee","year":"2020","journal-title":"Applied Sciences"},{"key":"2022052408564489400_CIT0043","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jpor.2015.06.002","article-title":"Comparison of repeatability between intraoral digital scanner and extraoral digital scanner: an in-vitro study","volume":"59","author":"Su","year":"2015","journal-title":"Journal of Prosthodontic Research"},{"key":"2022052408564489400_CIT0044","doi-asserted-by":"crossref","first-page":"108","DOI":"10.4103\/jips.jips_224_17","article-title":"A comparative evaluation of intraoral and extraoral digital impressions: an in vivo study","volume":"18","author":"Sason","year":"2018","journal-title":"Journal of Indian Prosthodontic Society"},{"key":"2022052408564489400_CIT0045","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1093\/ejo\/cjv077","article-title":"Accuracy, reliability, and efficiency of intraoral scanners for full-arch impressions: a systematic review of the clinical evidence","volume":"38","author":"Goracci","year":"2016","journal-title":"European Journal of Orthodontics"},{"key":"2022052408564489400_CIT0046","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1007\/s00056-017-0103-3","article-title":"Precision of guided scanning procedures for full-arch digital impressions in vivo","volume":"78","author":"Zimmermann","year":"2017","journal-title":"Journal of Orofacial Orthopedics"},{"key":"2022052408564489400_CIT0047","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jpor.2019.07.010","article-title":"Accuracy and practicality of intraoral scanner in dentistry: a literature review","volume":"64","author":"Kihara","year":"2020","journal-title":"Journal of Prosthodontic Research"}],"container-title":["European Journal of Orthodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ejo\/article-pdf\/44\/3\/279\/43780481\/cjab068.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ejo\/article-pdf\/44\/3\/279\/43780481\/cjab068.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T04:58:40Z","timestamp":1653368320000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejo\/article\/44\/3\/279\/6371447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,17]]},"references-count":47,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,9,17]]},"published-print":{"date-parts":[[2022,5,24]]}},"URL":"https:\/\/doi.org\/10.1093\/ejo\/cjab068","relation":{},"ISSN":["0141-5387","1460-2210"],"issn-type":[{"value":"0141-5387","type":"print"},{"value":"1460-2210","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,6,1]]},"published":{"date-parts":[[2021,9,17]]}}}