{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T11:23:53Z","timestamp":1770463433543,"version":"3.49.0"},"reference-count":51,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T00:00:00Z","timestamp":1657756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP19K10399"],"award-info":[{"award-number":["JP19K10399"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Orthodontic treatment for cleidocranial dysplasia (CCD) requires an understanding of the nature of the retained deciduous teeth, supernumerary teeth, delayed eruption of the permanent teeth, and craniofacial morphology from childhood to adulthood. This study aimed to provide an overview of the intraoral and craniofacial characteristics of growing and adult Japanese CCD subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We assessed cross-sectionally the intraoral features of 28 CCD subjects (males, 15.3 \u00b1 7.0 years; females, 15.2 \u00b1 5.1 years) using orthopantomograms and photographs. Mean facial diagrams (profilograms) of 3 age groups (5\u201310 years, 11\u201314 years, over 15 years: adult) were constructed, and linear and angular measurements of 2 age groups (under 15 years, adult) were performed by using cephalograms. The data were compared with Japanese standards.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A mean of 11.7 and 8.4 retained deciduous teeth, 10.4 and 15.8 erupted permanent teeth were observed in the adult males and females, and a mean of 6.8 and 5.3 supernumerary teeth were observed in all males and females, respectively. A positive correlation was found between the number of supernumerary teeth and the age at initial visit. Cephalometric analysis showed an average to anteriorly positioned maxilla, a tendency for counter-clockwise rotation of the ramus, and a prognathic mandible in all groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The number of supernumerary teeth increased with age. The maxilla was average to anteriorly positioned, and the mandible was counter-clockwise rotated and prognathic for all groups. These characteristic craniofacial morphologies and changes of intraoral conditions at different ages in CCD patients should be considered when proposing rational orthodontic treatment plans.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ejo\/cjac039","type":"journal-article","created":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T11:21:42Z","timestamp":1657797702000},"page":"711-722","source":"Crossref","is-referenced-by-count":6,"title":["An overview of the intraoral features and craniofacial morphology of growing and adult Japanese cleidocranial dysplasia subjects"],"prefix":"10.1093","volume":"44","author":[{"given":"Eric","family":"Shih-Wei Cheng","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Dental Sciences, Tokyo Medical and Dental University , Tokyo , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiko","family":"Tsuji","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Dental Sciences, Tokyo Medical and Dental University , Tokyo , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Dental Sciences, Tokyo Medical and Dental University , Tokyo , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0580-4510","authenticated-orcid":false,"given":"Keiji","family":"Moriyama","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Dental Sciences, Tokyo Medical and Dental University , Tokyo , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,7,14]]},"reference":[{"key":"2022120109330862400_CIT0001","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1259\/dmfr\/63490079","article-title":"Dentomaxillofacial variability of cleidocranial dysplasia: clinicoradiological presentation and systematic review","volume":"32","author":"Golan","year":"2003","journal-title":"Dentomaxillofacial Radiology"},{"key":"2022120109330862400_CIT0002","doi-asserted-by":"crossref","first-page":"178","DOI":"10.2319\/111307-393.1","article-title":"Orthodontic treatment in a patient with cleidocranial dysostosis","volume":"79","author":"Farronato","year":"2009","journal-title":"The Angle Orthodontist"},{"key":"2022120109330862400_CIT0003","doi-asserted-by":"crossref","first-page":"5","DOI":"10.2214\/ajr.121.1.5","article-title":"Cleidocranial dysostosis. 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