{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T08:21:42Z","timestamp":1781857302951,"version":"3.54.5"},"reference-count":46,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Academy for Health and Care"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,31]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Few studies within orthodontics present both economic and clinical findings. Missing maxillary lateral incisors is a frequently occurring anomaly. The treatment alternatives most used are orthodontic space closure and prosthetic replacement of the missing tooth. Our aim is to compare the total societal costs of orthodontic space closure (SC) and implant therapy (IT) in patients missing maxillary lateral incisors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Records of 32 patients treated with SC (n = 18) or IT (n = 14) due to missing maxillary lateral incisors were retrieved from the archives. Direct costs and indirect costs in the short- and long-term were analysed using a cost analysis with a societal perspective up of to 12 years post-treatment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Comparing cases treated with SC and IT, the difference in direct short-term costs for treatment is \u20ac735.54, whereas SC is the least costly. There is no difference between SC and IT in short-term parent loss of productivity, long-term loss of productivity, costs for transportation, or direct long-term costs. A difference was found between SC and IT\u2014in favour of SC\u2014when comparing patients\u2019 loss of productivity (P = 0.007), short-term societal costs (P &amp;lt; 0.001), long-term societal costs (P = 0.037), and total societal costs (P &amp;lt; 0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Limitations<\/jats:title>\n                  <jats:p>There is a limited number of patient records. Local factors such as subsidies, urban versus rural areas, taxes, etc. can influence monetary variables, so the transferability to other settings may be limited.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Patients treated with SC have a lower total societal cost compared to patients treated with IT. There was a difference in productivity loss for patients between SC and IT; however, concerning other indirect parameters and direct long-term costs, there was no difference between the two treatments.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ejo\/cjad008","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T20:55:33Z","timestamp":1681851333000},"page":"468-474","source":"Crossref","is-referenced-by-count":8,"title":["A cost analysis of orthodontic space closure and implant treatment in patients missing maxillary lateral incisors with a long-term perspective"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9450-2356","authenticated-orcid":false,"given":"Cecilia","family":"Hedmo","sequence":"first","affiliation":[{"name":"Department of Orthodontics, The Institute for Postgraduate Dental Education , J\u00f6nk\u00f6ping , Sweden"},{"name":"School of Health and Welfare, J\u00f6nk\u00f6ping University , J\u00f6nk\u00f6ping , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3223-0068","authenticated-orcid":false,"given":"Rune","family":"Lindsten","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, The Institute for Postgraduate Dental Education , J\u00f6nk\u00f6ping , Sweden"},{"name":"School of Health and Welfare, J\u00f6nk\u00f6ping University , J\u00f6nk\u00f6ping , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Josefsson","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, The Institute for Postgraduate Dental Education , J\u00f6nk\u00f6ping , Sweden"},{"name":"School of Health and Welfare, J\u00f6nk\u00f6ping University , J\u00f6nk\u00f6ping , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Davidson","sequence":"additional","affiliation":[{"name":"Department of Health, Medicine and Caring Sciences, Link\u00f6ping University , Link\u00f6ping , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,4,18]]},"reference":[{"key":"2023073113443813900_CIT0001","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1093\/ejo\/cjv040","article-title":"Health economic evaluations in orthodontics: a systematic review","volume":"38","author":"Sollenius","year":"2016","journal-title":"European Journal of Orthodontics"},{"key":"2023073113443813900_CIT0002","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1093\/ejo\/cjac019","article-title":"Cost-effectiveness of orthodontics: a systematic review","volume":"44","author":"Jermyn","year":"2022","journal-title":"European Journal of Orthodontics"},{"key":"2023073113443813900_CIT0003","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/sj.bdj.4800444","article-title":"Economic evaluation of healthcare\u2014Is it important to us","volume":"188","author":"Cunningham","year":"2000","journal-title":"British Dental Journal"},{"key":"2023073113443813900_CIT0004","volume-title":"Methods for the Economic Evaluation of Health Care Programmes","author":"Drummond","year":"2015"},{"key":"2023073113443813900_CIT0005","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/B978-0-12-802103-3.00034-1","article-title":"Chapter 33\u2014Pharmacoeconomics in Healthcare","volume-title":"Pharmaceutical Medicine and Translational Clinical Research","author":"Rai","year":"2018"},{"key":"2023073113443813900_CIT0006","first-page":"253","article-title":"Direct costs","volume-title":"Encyclopedia of Public Health","author":"Kirch","year":"2008"},{"key":"2023073113443813900_CIT0007","first-page":"296","article-title":"Agenesis of maxillary lateral incisors: a global overview of the clinical problem","volume":"12","author":"Kavadia","year":"2011","journal-title":"Orthodontics: The Art and Practice of Dentofacial Enhancement"},{"key":"2023073113443813900_CIT0008","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1600-0528.2004.00158.x","article-title":"A meta-analysis of the prevalence of dental agenesis of permanent teeth","volume":"32","author":"Polder","year":"2004","journal-title":"Community Dentistry and Oral Epidemiology"},{"key":"2023073113443813900_CIT0009","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1093\/ejo\/22.6.697","article-title":"The congenitally missing upper lateral incisor. 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